Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation
(2020)
Journal Article
Kolmert, J., Gómez, C., Balgoma, D., Sjödin, M., Bood, J., Konradsen, J. R., …U-BIOPRED Study Group. (2021). Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation. American Journal of Respiratory and Critical Care Medicine, 203(1), 37–53. https://doi.org/10.1164/rccm.201909-1869oc
Rationale: New approaches are needed to guide personalized treatment of asthma.
Objective: To test if urinary eicosanoid metabolites can direct asthma phenotyping.
Methods: Urinary metabolites of prostaglandins (PG), cysteinyl-leukotrienes (LT)...
Read More about Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type-2 Inflammation.