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Mixed-Methods Study on Caregiver Strain, Quality of Life, and Perceived Health (2021)
Journal Article
Di Lorito, C., Bosco, A., Godfrey, M., Dunlop, M., Lock, J., Pollock, K., Harwood, R. H., & van der Wardt, V. (2021). Mixed-Methods Study on Caregiver Strain, Quality of Life, and Perceived Health. Journal of Alzheimer's Disease, 80(2), 799-811. https://doi.org/10.3233/JAD-201257

Background:
Caring for someone with dementia is associated with negative and positive experiences. There is little evidence based on large datasets.

Objective:
To present data around the experience of caring for someone with dementia, to identif... Read More about Mixed-Methods Study on Caregiver Strain, Quality of Life, and Perceived Health.

What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism? (2021)
Journal Article
Arora, I., Bellato, A., Gliga, T., Ropar, D., Kochhar, P., Hollis, C., & Groom, M. (2022). What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism?. Journal of Autism and Developmental Disorders, 52(2), 600–616. https://doi.org/10.1007/s10803-021-04961-6

Slower habituation to repeating stimuli characterises Autism, but it is not known whether this is driven by difficulties with information processing or an attentional bias towards sameness. We conducted eye-tracking and presented looming geometrical... Read More about What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism?.

Resource allocation across the dementia continuum: a mixed methods study examining decision making on optimal dementia care among health and social care professionals (2021)
Journal Article
Keogh, F., Pierse, T., Challis, D., & O’Shea, E. (2021). Resource allocation across the dementia continuum: a mixed methods study examining decision making on optimal dementia care among health and social care professionals. BMC Health Services Research, 21(1), Article 243. https://doi.org/10.1186/s12913-021-06230-9

Background: The understanding of appropriate or optimal care is particularly important for dementia, characterised by multiple, long-term, changing needs and the increasing expectations of people using services. However, the response of health and so... Read More about Resource allocation across the dementia continuum: a mixed methods study examining decision making on optimal dementia care among health and social care professionals.

Delirium and Delirium Severity Predict the Trajectory of the Hierarchical Assessment of Balance and Mobility in Hospitalized Older People: Findings From the DECIDE Study (2021)
Journal Article
Richardson, S., Murray, J., Davis, D., Stephan, B. C., Robinson, L., Brayne, C., Barnes, L., Parker, S., Sayer, A., Dodds, R., & Allan, L. (2022). Delirium and Delirium Severity Predict the Trajectory of the Hierarchical Assessment of Balance and Mobility in Hospitalized Older People: Findings From the DECIDE Study. Journals of Gerontology, Series A, 77(3), 531–535. https://doi.org/10.1093/gerona/glab081

Background:
Delirium is common, distressing and associated with poor outcomes. Despite this, delirium remains poorly recognised, resulting in worse outcomes. There is an urgent need for methods to objectively assess for delirium. Physical functio... Read More about Delirium and Delirium Severity Predict the Trajectory of the Hierarchical Assessment of Balance and Mobility in Hospitalized Older People: Findings From the DECIDE Study.

Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial (2021)
Journal Article
Williams, L., Hall, C. L., Brown, S., Guo, B., James, M., Franceschini, M., Clarke, J., Selby, K., Vijayan, H., Kulkarni, N., Brown, N., Sayal, K., Hollis, C., & Groom, M. J. (2021). Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial. Pilot and Feasibility Studies, 7, Article 68. https://doi.org/10.1186/s40814-021-00788-1

Background
Medication for attention deficit hyperactivity disorder (ADHD) should be closely monitored to ensure optimisation. There is growing interest in using computerised assessments of ADHD symptoms to support medication monitoring. The aim of t... Read More about Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial.

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study (2021)
Presentation / Conference Contribution
Briggs, L., Blake, H., Cirelli, C., Corner, J., Hassard, J., Daly, J., Chappell, J., Bennett, M., Fairclough, L., McClure, C., Tarr, A., Tighe, P., Favier, A., Irving, W., & Ball, J. (2021, March). Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study. Poster presented at RSM National Conference 2021, Online

Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study (2021)
Presentation / Conference Contribution
Briggs, L., Blake, H., Hassard, J., Cirelli, C., Daly, J., Corner, J., Bennett, M., Chappell, J., Fairclough, L., McClure, C., Tarr, A., Tighe, P., Favier, A., Irving, W., & Ball, J. (2021, March). Perceptions and Experiences of the University of Nottingham Pilot SARS-CoV-2 Asymptomatic Testing Service: A Mixed-Methods Study. Poster presented at MedAll International Virtual Medical Conference, Online

Measuring Online Wellbeing: A Scoping Review of Subjective Wellbeing Measures (2021)
Journal Article
Ong, Z. X., Dowthwaite, L., Vallejos, E. P., & Long, Y. (2021). Measuring Online Wellbeing: A Scoping Review of Subjective Wellbeing Measures. Frontiers in Psychology, 12, Article 616637. https://doi.org/10.3389/fpsyg.2021.616637

With the increasing importance of the internet to our everyday lives, questions are rightly being asked about how its’ use affects our wellbeing. It is important to be able to effectively measure the effects of the online context as it allows us to a... Read More about Measuring Online Wellbeing: A Scoping Review of Subjective Wellbeing Measures.

Resource allocation in dementia care: comparing the views of people with dementia, carers and health and social care professionals under constrained and unconstrained budget scenarios (2021)
Journal Article
Pierse, T., Keogh, F., Challis, D., & O’Shea, E. (2022). Resource allocation in dementia care: comparing the views of people with dementia, carers and health and social care professionals under constrained and unconstrained budget scenarios. Aging and Mental Health, 26(4), 679-687. https://doi.org/10.1080/13607863.2021.1889969

Background: People with dementia and their carers have a wide range of health and social care needs. People with dementia, carers and health and social care professionals (HSCPs) all have different perspectives on dementia care. Differences among the... Read More about Resource allocation in dementia care: comparing the views of people with dementia, carers and health and social care professionals under constrained and unconstrained budget scenarios.

Is autonomic function during resting-state atypical in Autism: A systematic review of evidence (2021)
Journal Article
Arora, I., Bellato, A., Ropar, D., Hollis, C., & Groom, M. (2021). Is autonomic function during resting-state atypical in Autism: A systematic review of evidence. Neuroscience and Biobehavioral Reviews, 125, 417-441. https://doi.org/10.1016/j.neubiorev.2021.02.041

Background: Theories of differences in resting-state arousal in autistic individuals are influential. Differences in arousal during resting-state would impact engagement and adaptation to the environment, having a cascading effect on development of a... Read More about Is autonomic function during resting-state atypical in Autism: A systematic review of evidence.

The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial (2021)
Journal Article
Browning, M., Bilderbeck, A. C., Dias, R., Dourish, C. T., Kingslake, J., Deckert, J., Goodwin, G. M., Gorwood, P., Guo, B., Harmer, C. J., Morriss, R., Reif, A., Ruhe, H. G., Van Schaik, A., Simon, J., Sola, V. P., Veltman, D. J., Elices, M., Lever, A. G., Menke, A., …Dawson, G. R. (2021). The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial. Neuropsychopharmacology, 46, 1307–1314. https://doi.org/10.1038/s41386-021-00981-z

Depressed patients often do not respond to the first antidepressant prescribed, resulting in sequential trials of different medications. Personalised medicine offers a means of reducing this delay, however the clinical effectiveness of personalised a... Read More about The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial.

Hormone replacement therapy and dementia risk: nested case-control studies using CPRD and QResearch (2021)
Journal Article
Vinogradova, Y., Dening, T., Hippisley-Cox, J., Taylor, L., Moore, M., & Coupland, C. (2021). Hormone replacement therapy and dementia risk: nested case-control studies using CPRD and QResearch. East Midlands Research into Ageing Network (EMRAN) Discussion Paper Series, 38, 1-16

Introduction: Research from clinical trials of hormone replacement therapy (HRT) has produced conflicting findings about possible risks of dementia after receiving these treatments, and further research on HRT and dementia risk has been identified as... Read More about Hormone replacement therapy and dementia risk: nested case-control studies using CPRD and QResearch.

Promoting independence in Dementia (Pride): A feasibility randomized controlled trial (2021)
Journal Article
Csipke, E., Shafayat, A., Sprange, K., Bradshaw, L., Montgomery, A. A., Ogollah, R., Moniz-Cook, E., & Orrell, M. (2021). Promoting independence in Dementia (Pride): A feasibility randomized controlled trial. Clinical Interventions in Aging, 16, 363-378. https://doi.org/10.2147/CIA.S281139

© 2021 Csipke et al. Background: There is a need for interventions to foster and maintain independence for people with dementia to support community living, improve morale, and reduce stigma. We investigated a social intervention to promote living we... Read More about Promoting independence in Dementia (Pride): A feasibility randomized controlled trial.

The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain (2021)
Journal Article
Akin-Akinyosoye, K., James, R. J. E., Mcwilliams, D. F., Millar, B., Das Nair, R., Ferguson, E., & Walsh, D. A. (2021). The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain. Osteoarthritis and Cartilage, 29(6), 802-814. https://doi.org/10.1016/j.joca.2021.02.562

OBJECTIVES: Pain is the prevailing symptom of knee osteoarthritis. Central sensitisation creates discordance between pain and joint pathology. We previously reported a central pain mechanisms trait derived from 8 discrete characteristics: neuropathic... Read More about The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain.

Therapist competence and clinical outcome in the rehabilitation of memory following traumatic brain injury trial (2021)
Journal Article
Trigg, E., Clarke, S., Wong, D., & Nair, R. (2021). Therapist competence and clinical outcome in the rehabilitation of memory following traumatic brain injury trial. Brain Injury, 35(4), 395-403. https://doi.org/10.1080/02699052.2021.1877817

Objectives: Therapist competencies when delivering an intervention can impact clinical outcomes. However, the relationship between competence and outcome in the context of memory rehabilitation has not previously been investigated. We aimed to evalua... Read More about Therapist competence and clinical outcome in the rehabilitation of memory following traumatic brain injury trial.

Delivering personalised home care for people with dementia: an investigation of care providers' roles and responsibilities (2021)
Journal Article
Sutcliffe, C., Davies, K., Ahmed, S., Hughes, J., & Challis, D. (2021). Delivering personalised home care for people with dementia: an investigation of care providers' roles and responsibilities. Journal of Long-Term Care, 2021, 58-69. https://doi.org/10.31389/jltc.35

Context: Home care agencies are a critical part of the social care system in England, however little is known of how they perceive their role in delivering personalised care or their approach to supporting people with dementia.
Objectives: To inves... Read More about Delivering personalised home care for people with dementia: an investigation of care providers' roles and responsibilities.

Tele-Rehabilitation for People with Dementia during the COVID-19 Pandemic: A Case-Study from England (2021)
Journal Article
Di Lorito, C., Duff, C., Rogers, C., Tuxworth, J., Bell, J., Fothergill, R., Wilkinson, L., Bosco, A., Howe, L., O’Brien, R., Godfrey, M., Dunlop, M., van der Wardt, V., Booth, V., Logan, P., Cowley, A., & Harwood, R. H. (2021). Tele-Rehabilitation for People with Dementia during the COVID-19 Pandemic: A Case-Study from England. International Journal of Environmental Research and Public Health, 18(4), Article 1717. https://doi.org/10.3390/ijerph18041717

Introduction: The Promoting Activity, Independence and Stability in Early Dementia (PrAISED) is delivering an exercise programme for people with dementia. The Lincolnshire partnership National Health Service (NHS) foundation Trust successfully delive... Read More about Tele-Rehabilitation for People with Dementia during the COVID-19 Pandemic: A Case-Study from England.

Early Warning Signs of a Mental Health Tsunami: A Coordinated Response to Gather Initial Data Insights From Multiple Digital Services Providers (2021)
Journal Article
Inkster, B., & Digital Mental Health Data Insights Group (DMHDIG). (2021). Early Warning Signs of a Mental Health Tsunami: A Coordinated Response to Gather Initial Data Insights From Multiple Digital Services Providers. Frontiers in Digital Health, 2, Article 578902. https://doi.org/10.3389/fdgth.2020.578902

Introduction: The immediate impact of coronavirus 2019 (COVID-19) on morbidity and mortality has raised the need for accurate and real-time data monitoring and communication. The aim of this study is to document the initial observations from multiple... Read More about Early Warning Signs of a Mental Health Tsunami: A Coordinated Response to Gather Initial Data Insights From Multiple Digital Services Providers.

PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression (2021)
Preprint / Working Paper
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Hollis, C., Hippisley-Cox, J., & Coupland, C. PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression

This protocol describes a cohort study comparing the risks of mortality and serious self-harm (suicide or near-fatal deliberate self-harm) between adults with depression prescribed mirtazapine, a selective serotonin reuptake inhibitor (SSRI), amitrip... Read More about PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression.