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All Outputs (939)

School-based behaviour change intervention to increase physical activity levels among children: A feasibility cluster non-randomised controlled trial in Yangzhou, China (2021)
Journal Article
Wang, H., Blake, H., & Chattopadhyay, K. (2021). School-based behaviour change intervention to increase physical activity levels among children: A feasibility cluster non-randomised controlled trial in Yangzhou, China. BMJ Open, 11(10), Article e052659. https://doi.org/10.1136/bmjopen-2021-052659

Children in China have low levels of physical activity. We developed a school-based behaviour change intervention to increase their physical activity levels. The study aimed to determine the feasibility of undertaking a cluster randomised controlled... Read More about School-based behaviour change intervention to increase physical activity levels among children: A feasibility cluster non-randomised controlled trial in Yangzhou, China.

Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum (2021)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Taal, M. W., Aithal, G. P., Zhang, W., …Abhishek, A. (2022). Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum. Rheumatology, 61(7), 2783-2791. https://doi.org/10.1093/rheumatology/keab790

OBJECTIVE: To develop and validate a prognostic model for LEF discontinuation with abnormal blood test results. METHODS: Data from the Clinical Practice Research Datalink Gold and Aurum were used for model development and external validation, respect... Read More about Development and validation of a prognostic model for leflunomide discontinuation with abnormal blood tests during long-term treatment: cohort study using data from the Clinical Practice Research Datalink Gold and Aurum.

COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project (2021)
Journal Article
Rutter, M., Lanyon, P. C., Grainge, M. J., Hubbard, R., Peach, E., Bythell, M., …Pearce, F. A. (2022). COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project. Rheumatology, 61(8), 3161-3171. https://doi.org/10.1093/rheumatology/keab794

Objectives: To calculate the rates of COVID-19 infection and COVID-19-related death among people with rare autoimmune rheumatic diseases (RAIRD) during the first wave of the COVID-19 pandemic in England compared to the general population.

Methods... Read More about COVID-19 infection, admission and death among people with rare autoimmune rheumatic disease in England: results from the RECORDER project.

36-month evaluation of a weight management programme in Chinese overweight and obese adults (2021)
Journal Article
Yang, X., Chattopadhyay, K., Hubbard, R., Li, J.-L., Li, L., & Lin, Y. (2021). 36-month evaluation of a weight management programme in Chinese overweight and obese adults. Frontiers in Public Health, 9, Article 749302

Background: Few comprehensive lifestyle intervention programmes have been investigated on overweight and obese adults in China. This study was to evaluate the effect of a 36-month weight management programme on weight loss and its maintenance among o... Read More about 36-month evaluation of a weight management programme in Chinese overweight and obese adults.

Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention (2021)
Journal Article
Knight, H., Jia, R., Ayling, K., Bradbury, K., Baker, K., Chalder, T., …Vedhara, K. (2021). Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention. Public Health, 201, 98-107. https://doi.org/10.1016/j.puhe.2021.10.006

Objectives: Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) was identified in late 2019, spreading to over 200 countries and resulting in almost two million deaths worldwide. The emergence of safe and effective vaccines provides a route out of th... Read More about Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention.

Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: A prospective, multicentre cohort study (2021)
Journal Article
Sullivan, M. K., Lees, J. S., Drake, T. M., Docherty, A. B., Oates, G., Hardwick, H. E., …Mark, P. B. (2022). Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: A prospective, multicentre cohort study. Nephrology Dialysis Transplantation, 37(2), 271-284. https://doi.org/10.1093/ndt/gfab303

Background: Acute kidney injury (AKI) is common in coronavirus disease 2019 (COVID-19). This study investigated adults hospitalized with COVID-19 and hypothesized that risk factors for AKI would include comorbidities and non-White race. Methods: A pr... Read More about Acute kidney injury in patients hospitalized with COVID-19 from the ISARIC WHO CCP-UK Study: A prospective, multicentre cohort study.

Population‐based cohort study of the efficacy of brentuximab vedotin in relapsed systemic anaplastic large‐cell lymphoma using Public Health England data (2021)
Journal Article
Halligan, S. J., Grainge, M. J., Martinez-Calle, N., Fox, C. P., & Bishton, M. J. (2022). Population‐based cohort study of the efficacy of brentuximab vedotin in relapsed systemic anaplastic large‐cell lymphoma using Public Health England data. British Journal of Haematology, 196(4), 932-938. https://doi.org/10.1111/bjh.17896

Systemic anaplastic large cell lymphoma (sALCL) is a rare T-cell lymphoma associated with poor prognosis after relapse. The immuno-conjugate Brentuximab Vedotin (BV) first became available for relapsed sALCL in England in 2013, following the results... Read More about Population‐based cohort study of the efficacy of brentuximab vedotin in relapsed systemic anaplastic large‐cell lymphoma using Public Health England data.

Conduct and reporting of formula milk trials: systematic review (2021)
Journal Article
Helfer, B., Leonardi-Bee, J., Mundell, A., Parr, C., Ierodiakonou, D., Garcia-Larsen, V., …Boyle, R. J. (2021). Conduct and reporting of formula milk trials: systematic review. BMJ, 375, Article n2202. https://doi.org/10.1136/bmj.n2202

Importance: Formula milk is consumed by most infants in Europe and North America and global consumption is rising. New formula products need to be tested in clinical trials, but concerns have been raised that such trials are biased and may undermine... Read More about Conduct and reporting of formula milk trials: systematic review.

Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care (2021)
Journal Article
Qureshi, N., Akyea, R. K., Dutton, B., Leonardi-Bee, J., Humphries, S. E., Weng, S., & Kai, J. (2021). Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care. Open Heart, 8(2), Article e001752. https://doi.org/10.1136/openhrt-2021-001752

Objective Familial hypercholesterolaemia (FH) is a common inherited disorder causing premature coronary heart disease (CHD) and death. We have developed the novel Familial Hypercholesterolaemia Case Ascertainment Tool (FAMCAT 1) case-finding algorith... Read More about Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care.

Risk of subtrochanteric and femoral shaft fractures due to bisphosphonate therapy in asthma: a population-based nested case–control study (2021)
Journal Article
Chalitsios, C. V., Shaw, D. E., & McKeever, T. M. (2021). Risk of subtrochanteric and femoral shaft fractures due to bisphosphonate therapy in asthma: a population-based nested case–control study. Osteoporosis International, https://doi.org/10.1007/s00198-021-06197-7

Summary: Concerns have been raised over the association between bisphosphonates and atypical fractures in subtrochanteric and femoral shaft regions, but the potential risk of these fractures due to bisphosphonate use in asthma has not been examined.... Read More about Risk of subtrochanteric and femoral shaft fractures due to bisphosphonate therapy in asthma: a population-based nested case–control study.

Strategies for screening for familial hypercholesterolaemia in primary care and other community settings (2021)
Journal Article
Qureshi, N., Da Silva, M. L. R., Abdul-Hamid, H., Weng, S. F., Kai, J., & Leonardi-Bee, J. (2021). Strategies for screening for familial hypercholesterolaemia in primary care and other community settings. Cochrane Database of Systematic Reviews, 2021(10), Article CD012985. https://doi.org/10.1002/14651858.cd012985.pub2

Background: Familial hypercholesterolaemia is a common inherited condition that is associated with premature cardiovascular disease. The increased cardiovascular morbidity and mortality, resulting from high levels of cholesterol since birth, can be p... Read More about Strategies for screening for familial hypercholesterolaemia in primary care and other community settings.

Evaluating stroke early supported discharge using cost-consequence analysis (2021)
Journal Article
Byrne, A., Chouliara, N., Cameron, T., Geue, C., Lewis, S., Robinson, T., …Fisher, R. J. (2022). Evaluating stroke early supported discharge using cost-consequence analysis. Disability and Rehabilitation, 44(23), 7127-7133. https://doi.org/10.1080/09638288.2021.1983043

Purpose: To evaluate different stroke Early Supported Discharge (ESD) services in different geographical settings using cost-consequence analysis (CCA), which presents information about costs and outcomes in the form of a balance sheet. ESD is a mult... Read More about Evaluating stroke early supported discharge using cost-consequence analysis.

Motivation and willingness to increase physical activity for dementia risk reduction: Cross-Sectional UK survey with people aged 50 and over (2021)
Journal Article
Oliveira, D., Knight, H., Jones, K. A., Ogollah, R., & Orrell, M. (2022). Motivation and willingness to increase physical activity for dementia risk reduction: Cross-Sectional UK survey with people aged 50 and over. Aging and Mental Health, 26(9), 1899-1908. https://doi.org/10.1080/13607863.2021.1984393

Objective:Tackling modifiable risk factors such as physical inactivity currently represents the only way to reduce the increasing prevalence of dementia worldwide. This study aimed to investigate attitudes to increasing physical activity to reduce ri... Read More about Motivation and willingness to increase physical activity for dementia risk reduction: Cross-Sectional UK survey with people aged 50 and over.

Proportion of School Attending Adolescents Meeting the Recommended Moderate-to-Vigorous Physical Activity Level and Its Predictors in Lagos, Nigeria (2021)
Journal Article
Adebusoye, B., Leonardi-Bee, J., Phalkey, R., & Chattopadhyay, K. (2021). Proportion of School Attending Adolescents Meeting the Recommended Moderate-to-Vigorous Physical Activity Level and Its Predictors in Lagos, Nigeria. International Journal of Environmental Research and Public Health, 18(20), Article 10744. https://doi.org/10.3390/ijerph182010744

We aimed to assess the proportion of school attending adolescents who reached the recommended moderate-to-vigorous physical activity (MVPA) level in Lagos State, Nigeria as well as the predictors associated with it. A cross-sectional study was conduc... Read More about Proportion of School Attending Adolescents Meeting the Recommended Moderate-to-Vigorous Physical Activity Level and Its Predictors in Lagos, Nigeria.

Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis (2021)
Journal Article
Leonardi-Bee, J., Boateng, C., Faria, R., Eliman, K., Young, B., & Qureshi, N. (2021). Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis. Atherosclerosis, 338, 7-14. https://doi.org/10.1016/j.atherosclerosis.2021.09.014

Background and aims: Cascade testing in relatives of index cases is the most cost-effective approach to identifying people with familial hypercholesterolemia (FH); however, it is currently unclear which strategy to contact relatives would be the most... Read More about Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis.

Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study (2021)
Journal Article
Knight, H., Carlisle, S., O’connor, M., Briggs, L., Fothergill, L., Al-Oraibi, A., …Blake, H. (2021). Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study. International Journal of Environmental Research and Public Health, 18(20), Article 10675. https://doi.org/10.3390/ijerph182010675

This qualitative study explored the impact of COVID-19 self-isolation and social restriction measures on university students, through the perspectives of both students and the staff supporting them. The study comprised 11 focus groups (students) and... Read More about Impacts of the COVID-19 pandemic and self-isolation on students and staff in higher education: A qualitative study.

Spotlight influenza: Laboratory-confirmed seasonal influenza in people with acute respiratory illness: a literature review and meta-analysis, WHO European Region, 2004 to 2017 (2021)
Journal Article
Belazi, S., Olsen, S. J., Brown, C., Green, H. K., Mook, P., Nguyen-Van-Tam, J., …Lansbury, L. (2021). Spotlight influenza: Laboratory-confirmed seasonal influenza in people with acute respiratory illness: a literature review and meta-analysis, WHO European Region, 2004 to 2017. Eurosurveillance, 26(39), https://doi.org/10.2807/1560-7917.es.2021.26.39.2000343

BackgroundAcross the World Health Organization European Region, there are few estimates of the proportion of people seeking medical care for influenza-like illness or acute respiratory infections and who have laboratory-confirmed seasonal influenza i... Read More about Spotlight influenza: Laboratory-confirmed seasonal influenza in people with acute respiratory illness: a literature review and meta-analysis, WHO European Region, 2004 to 2017.

Initial impact of the COVID-19 pandemic on public health training: participatory action research to understand experiences in the East Midlands (2021)
Journal Article
Maile, E. L., Horsley, S. M., Dunn, T., Knight, J. M., Brough, G., Davies, N., …Cooper, R. (2024). Initial impact of the COVID-19 pandemic on public health training: participatory action research to understand experiences in the East Midlands. Journal of Public Health, 45(1), 162-168. https://doi.org/10.1093/pubmed/fdab348

Background

Specialty public health training consists of 48 months of practice across the domains of health protection, healthcare public health and health improvement. With the onset of the COVID-19 pandemic, activity pivoted towards pandemic man... Read More about Initial impact of the COVID-19 pandemic on public health training: participatory action research to understand experiences in the East Midlands.

Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials (2021)
Journal Article
Kundakci, B., Kaur, J., Goh, S. L., Hall, M., Doherty, M., Zhang, W., & Abhishek, A. (2022). Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials. PAIN, 163(8), 1432-1445. https://doi.org/10.1097/j.pain.0000000000002500

Fibromyalgia is a highly heterogeneous condition, but the most common symptoms are widespread pain, fatigue, poor sleep, and low mood. Nonpharmacological interventions are recommended as first-line treatment of fibromyalgia. However which interventio... Read More about Efficacy of nonpharmacological interventions for individual features of fibromyalgia: a systematic review and meta-analysis of randomised controlled trials.

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study (2021)
Journal Article
Hippisley-Cox, J., Coupland, C. A., Mehta, N., Keogh, R. H., Diaz-Ordaz, K., Khunti, K., …Nguyen-Van-Tam, J. S. (2021). Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study. BMJ, 374, Article n2244. https://doi.org/10.1136/bmj.n2244

Objectives To derive and validate risk prediction algorithms to estimate the risk of covid-19 related mortality and hospital admission in UK adults after one or two doses of covid-19 vaccination. Design Prospective, population based cohort study usin... Read More about Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study.