All Outputs (1126)

Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions (2014)
Journal Article
Gibson, C. L., Srivastava, K., Sprigg, N., Bath, P. M., & Bayrakutan, U. (in press). Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions. Journal of Neurochemistry, 129(5), https://doi.org/10.1111/jnc.12681

Ischaemic strokes evoke blood–brain barrier (BBB) disruption and oedema formation through a series of mechanisms involving Rho-kinase activation. Using an animal model of human focal cerebral ischaemia, this study assessed and confirmed the therapeut... Read More about Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions.

A method for measuring the intelligibility of uninterrupted, continuous speech (2014)
Journal Article
MacPherson, A., & Akeroyd, M. A. (2014). A method for measuring the intelligibility of uninterrupted, continuous speech. Journal of the Acoustical Society of America, 135(3), 1027-1030. https://doi.org/10.1121/1.4863657

Speech-in-noise tests commonly use short, discrete sentences as representative samples of everyday speech. These tests cannot, however, fully represent the added demands of understanding ongoing, linguistically complex speech. Using a new monitoring... Read More about A method for measuring the intelligibility of uninterrupted, continuous speech.

Statistical analysis plan for the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial (2014)
Journal Article
Bath, P. M., Houlton, A., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., & Pocock, S. J. (in press). Statistical analysis plan for the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial. International Journal of Stroke, 9(3), https://doi.org/10.1111/ijs.12235

High blood pressure is common during the acute phase of stroke and is associated with a poor outcome. However, the management of high blood pressure remains unclear. The ‘Efficacy of Nitric Oxide in Stroke’ trial tested whether transdermal glyceryl t... Read More about Statistical analysis plan for the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial.

Anaesthetic corneas with intact sub-basal nerve plexus (2014)
Journal Article

The effect of hyperglycaemia on permeability and the expression of junctional complex molecules in human retinal and choroidal endothelial cells. (2014)
Journal Article

Diabetic retinopathy is the leading cause of preventable blindness in the working population and its prevalence continues to increase as the worldwide prevalence of diabetes grows. Diabetic choroidopathy is less well studied and occurs in the late st... Read More about The effect of hyperglycaemia on permeability and the expression of junctional complex molecules in human retinal and choroidal endothelial cells..

TrkB-Mediated Protection against Circadian Sensitivity to Noise Trauma in the Murine Cochlea (2014)
Journal Article
Meltser, I., Cederroth, C., Basinou, V., Savelyev, S., Lundkvist, G., & Canlon, B. (2017). TrkB-Mediated Protection against Circadian Sensitivity to Noise Trauma in the Murine Cochlea. Current Biology, 24(6), 658-663. https://doi.org/10.1016/j.cub.2014.01.047

Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting (2014)
Journal Article

Tobacco smoking and excess mortality in multiple sclerosis: a cohort study (2014)
Journal Article
Constantinescu, C. S., Britton, J., Manouchehrinia, A., CONSTANTINESCU, C., Weston, M., & Tench, C. R. (2014). Tobacco smoking and excess mortality in multiple sclerosis: a cohort study. Journal of Neurology, Neurosurgery and Psychiatry, 85(10), 1091-1095. https://doi.org/10.1136/jnnp-2013-307187

XeNA: An automated 'open-source' 129Xe hyperpolarizer for clinical use (2014)
Journal Article
Nikolaou, P., Barlow, M., Coffey, A., Walkup, L., Gust, B., Whiting, N., …Goodson, B. (2014). XeNA: An automated 'open-source' 129Xe hyperpolarizer for clinical use. Magnetic Resonance Imaging, 32(5), 541-550. https://doi.org/10.1016/j.mri.2014.02.002

Concise review: evidence for CD34 as a common marker for diverse progenitors (2014)
Journal Article
Sidney, L. E., Branch, M. J., Dunphy, S. E., Dua, H. S., & Hopkinson, A. (2014). Concise review: evidence for CD34 as a common marker for diverse progenitors. STEM CELLS, 32(6), 1380-1389. https://doi.org/10.1002/stem.1661

CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and progenitor cells. Clinically, it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants. Due to these historical... Read More about Concise review: evidence for CD34 as a common marker for diverse progenitors.

Proposed norms for the Glasgow hearing-aid benefit profile (Ghabp) questionnaire (2014)
Journal Article
Whitmer, W. M., Howell, P., & Akeroyd, M. A. (2014). Proposed norms for the Glasgow hearing-aid benefit profile (Ghabp) questionnaire. International Journal of Audiology, 53(5), 345-351. https://doi.org/10.3109/14992027.2013.876110

Objective: To form a normative set of responses to the GHABP questionnaire from a large regional dataset. Design: Participants were asked to rate their hearing disability, handicap, hearing-aid (HA) use, HA benefit, HA satisfaction, and residual (aid... Read More about Proposed norms for the Glasgow hearing-aid benefit profile (Ghabp) questionnaire.

Patterns of hearing aid usage predict hearing aid use amount (data logged and self-reported) and overreport (2014)
Journal Article

Background: Previous studies found that, on average, users overreport their daily amount of hearing aid use compared to objective measures such as data logging. However, the reasons for this are unclear. Purpose: This study assessed data-logged and... Read More about Patterns of hearing aid usage predict hearing aid use amount (data logged and self-reported) and overreport.

Amplification with hearing aids for patients with tinnitus and co-existing hearing loss (2014)
Journal Article

Evaluation of the physiological properties of ventilatory ratio in a computational cardiopulmonary model and its clinical application in an acute respiratory distress syndrome population (2014)
Journal Article
Sinha, P., Hardman, J., Singh, S., Bersten, A. D., & Soni, N. C. (2014). Evaluation of the physiological properties of ventilatory ratio in a computational cardiopulmonary model and its clinical application in an acute respiratory distress syndrome population. British Journal of Anaesthesia, 112(1), 96-101. https://doi.org/10.1093/bja/aet283

Gameplay as a Source of Intrinsic Motivation in a Randomized Controlled Trial of Auditory Training for Tinnitus (2014)
Journal Article
Hoare, D. J., Sereda, M., Van Labeke, N., McCormack, A., Smith, S., Taher, H. A., …Hall, D. A. (2014). Gameplay as a Source of Intrinsic Motivation in a Randomized Controlled Trial of Auditory Training for Tinnitus. PLoS ONE, 9(9), Article e107430. https://doi.org/10.1371/journal.pone.0107430

Benefits of phoneme discrimination training in a randomized controlled trial of 50- to 74-year-olds with mild hearing loss (2014)
Journal Article
Ferguson, M. A., Henshaw, H., Clark, D., & Moore, D. R. (2014). Benefits of phoneme discrimination training in a randomized controlled trial of 50- to 74-year-olds with mild hearing loss. Ear and Hearing, 35(4), Article e110-e121. https://doi.org/10.1097/AUD.0000000000000020

Objectives: The aims of this study were to (i) evaluate the efficacy of phoneme discrimination training for hearing and cognitive abilities of adults aged 50 to 74 years with mild sensorineural hearing loss who were not users of hearing aids, and to... Read More about Benefits of phoneme discrimination training in a randomized controlled trial of 50- to 74-year-olds with mild hearing loss.

Assessing the benefits of auditory training to real-world listening: identifying appropriate and sensitive outcomes (2014)
Book Chapter
Henshaw, H., & Ferguson, M. A. (2014). Assessing the benefits of auditory training to real-world listening: identifying appropriate and sensitive outcomes. In T. Dau, & S. Santurette (Eds.), Auditory plasticity - listening with the brain. Danavox Jubilee Foundation

Auditory training is an intervention that aims to improve auditory performance and help alleviate the difficulties associated with hearing loss. To be an effective intervention, any task-specific learning needs to transfer to functional benefits in r... Read More about Assessing the benefits of auditory training to real-world listening: identifying appropriate and sensitive outcomes.

Optimal short-time acquisition schemes in high angular resolution diffusion-weighted imaging (2013)
Journal Article
Prčkovska, V., Achterberg, H. C., Bastiani, M., Pullens, P., Balmashnova, E., ter Haar Romeny, B. M., …Roebroeck, A. (2013). Optimal short-time acquisition schemes in high angular resolution diffusion-weighted imaging. International Journal of Biomedical Imaging, 2013, Article 658583. https://doi.org/10.1155/2013/658583

This work investigates the possibilities of applying high-angular-resolution-diffusion-imaging- (HARDI-) based methods in a clinical setting by investigating the performance of non-Gaussian diffusion probability density function (PDF) estimation for... Read More about Optimal short-time acquisition schemes in high angular resolution diffusion-weighted imaging.

Estimates of the number of adults in England, Wales, and Scotland with a hearing loss (2013)
Journal Article
Akeroyd, M. A., Foreman, K., & Holman, J. A. (2014). Estimates of the number of adults in England, Wales, and Scotland with a hearing loss. International Journal of Audiology, 53(1), 60-61. https://doi.org/10.3109/14992027.2013.850539

Orthogonal invariant sets of the diffusion tensor and the development of a curvilinear set suitable for low-anisotropy tissues (2013)
Journal Article
Damion, R. A., Radjenovic, A., Ingham, E., Jin, Z., & Ries, M. E. (2013). Orthogonal invariant sets of the diffusion tensor and the development of a curvilinear set suitable for low-anisotropy tissues. PLoS ONE, 8(11), Article e78798. https://doi.org/10.1371/journal.pone.0078798

We develop a curvilinear invariant set of the diffusion tensor which may be applied to Diffusion Tensor Imaging measurements on tissues and porous media. This new set is an alternative to the more common invariants such as fractional anisotropy and t... Read More about Orthogonal invariant sets of the diffusion tensor and the development of a curvilinear set suitable for low-anisotropy tissues.