All Outputs (1131)

The psychological and social consequences of single-sided deafness in adulthood (2017)
Journal Article
Lucas, L., Katiri, R., & Kitterick, P. T. (2018). The psychological and social consequences of single-sided deafness in adulthood. International Journal of Audiology, 57(1), 21-30. https://doi.org/10.1080/14992027.2017.1398420

Objectives: This study examined the subjective psychological and social effects of highly asymmetric hearing loss (single-sided deafness) in adults.
Design: Three group interviews were conducted using the critical incidence technique and analysed us... Read More about The psychological and social consequences of single-sided deafness in adulthood.

Patterns of grey matter loss associated with motor subscores in early Parkinson's disease (2017)
Journal Article
Li, X., Xing, Y., Martin-Bastida, A., Piccini, P., & Auer, D. P. (in press). Patterns of grey matter loss associated with motor subscores in early Parkinson's disease. NeuroImage: Clinical, 17, https://doi.org/10.1016/j.nicl.2017.11.009

Classical motor symptoms of Parkinson's disease (PD) such as tremor, rigidity, bradykinesia, and axial symptoms are graded in the Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III. It is yet to be ascertained whether... Read More about Patterns of grey matter loss associated with motor subscores in early Parkinson's disease.

Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population (2017)
Journal Article
Fackrell, K., Hall, D. A., Barry, J. G., & Hoare, D. J. (2018). Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population. Hearing Research, 358, https://doi.org/10.1016/j.heares.2017.10.016

Objectives: The Tinnitus Functional Index (TFI) has been optimised as a diagnostic tool for quantifying the functional impact of tinnitus in US veteran and civilian groups. However, the TFI has not been evaluated for use in other English-speaking cl... Read More about Performance of the Tinnitus Functional Index as a diagnostic instrument in a UK clinical population.

Relations between self-reported daily-life fatigue, hearing status and pupil dilation during a speech perception in noise task (2017)
Journal Article
Wang, Y., Naylor, G., Kramer, S. E., Zekveld, A. A., Wendt, D., Ohlenforst, B., & Lunner, T. (2018). Relations between self-reported daily-life fatigue, hearing status and pupil dilation during a speech perception in noise task. Ear and Hearing, 39(3), 573–582. https://doi.org/10.1097/AUD.0000000000000512

Objective: people with hearing impairment are likely to experience higher levels of fatigue due to effortful listening in daily communication. This hearing-related fatigue might not only constrain their work performance, but also result in withdrawal... Read More about Relations between self-reported daily-life fatigue, hearing status and pupil dilation during a speech perception in noise task.

Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation (2017)
Journal Article
Zgair, A., Lee, J. B., Wong, J. C. M., Taha, D. A., Aram, J., Virgilio, D. D., …Gershkovich, P. (2017). Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation. Scientific Reports, 7, 1-12. https://doi.org/10.1038/s41598-017-15026-z

Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) have well documented immunomodulatory effects in vitro, but not following oral administration in humans. Here we show that oral co-administration of cannabinoids with lipids can substantially increa... Read More about Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation.

Evaluation of a method for determining binaural sensitivity to temporal fine structure (TFS-AF test) for older listeners with normal and impaired low-frequency hearing (2017)
Journal Article
Füllgrabe, C., & Moore, B. C. (2017). Evaluation of a method for determining binaural sensitivity to temporal fine structure (TFS-AF test) for older listeners with normal and impaired low-frequency hearing. Trends in Hearing, 21, https://doi.org/10.1177/2331216517737230

The ability to process binaural temporal fine structure (TFS) information was assessed using the TFS-AF test (where AF stands for adaptive frequency) for 26 listeners aged 60 years or more with normal or elevated low-frequency audiometric thresholds.... Read More about Evaluation of a method for determining binaural sensitivity to temporal fine structure (TFS-AF test) for older listeners with normal and impaired low-frequency hearing.

Audiologist-guided internet-based cognitive behavior therapy for adults with tinnitus in the United Kingdom: a randomized controlled trial (2017)
Journal Article
Beukes, E. W., Baguley, D., Allen, P. M., Manchaiah, V., & Andersson, G. (in press). Audiologist-guided internet-based cognitive behavior therapy for adults with tinnitus in the United Kingdom: a randomized controlled trial. Ear and Hearing, https://doi.org/10.1097/AUD.0000000000000505

Objectives: Specialist tinnitus services are in high demand as a result of the negative effect tinnitus may have on quality of life. Additional clinically and cost-effective tinnitus management routes are needed. One potential route is providing Cogn... Read More about Audiologist-guided internet-based cognitive behavior therapy for adults with tinnitus in the United Kingdom: a randomized controlled trial.

Biomarkers of presbycusis and tinnitus in a Portuguese older population (2017)
Journal Article
Haider, H. F., Flook, M., Aparicio, M., Ribeiro, D., Antunes, M., Szczepek, A. J., …Caria, H. (2017). Biomarkers of presbycusis and tinnitus in a Portuguese older population. Frontiers in Aging Neuroscience, 9(346), https://doi.org/10.3389/fnagi.2017.00346

Introduction: Presbycusis or age-related hearing loss (ARHL) is a ubiquitous health problem. It is estimated that it will affect up to 1.5 billion people by 2025. In addition, tinnitus occurs in a large majority of cases with presbycusis. Glutamate m... Read More about Biomarkers of presbycusis and tinnitus in a Portuguese older population.

Effects of the cannabinoid CB1 agonist ACEA on salicylate ototoxicity, hyperacusis and tinnitus in guinea pigs (2017)
Journal Article
Berger, J. I., Coomber, B., Hill, S., Alexander, S., Owen, W., Palmer, A. R., & Wallace, M. N. (in press). Effects of the cannabinoid CB1 agonist ACEA on salicylate ototoxicity, hyperacusis and tinnitus in guinea pigs. Hearing Research, https://doi.org/10.1016/j.heares.2017.10.012

Cannabinoids have been suggested as a therapeutic target for a variety of brain disorders. Despite the presence of their receptors throughout the auditory system, little is known about how cannabinoids affect auditory function. We sought to determine... Read More about Effects of the cannabinoid CB1 agonist ACEA on salicylate ototoxicity, hyperacusis and tinnitus in guinea pigs.

Designing clinical trials for assessing the effectiveness of interventions for tinnitus (2017)
Journal Article
Hall, D. A. (2017). Designing clinical trials for assessing the effectiveness of interventions for tinnitus. Trends in Hearing, 21, https://doi.org/10.1177/2331216517736689

In the face of finite resources, allocations of research and healthcare funding are dependent upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing science, with low-quality clinical research providing unreliable esti... Read More about Designing clinical trials for assessing the effectiveness of interventions for tinnitus.

Effects of noise exposure on young adults with normal audiograms II: Behavioral measures (2017)
Journal Article
Prendergast, G., Millman, R. E., Guest, H., Munro, K. J., Kluk, K., Dewey, R. S., …Plack, C. J. (2017). Effects of noise exposure on young adults with normal audiograms II: Behavioral measures. Hearing Research, 356, https://doi.org/10.1016/j.heares.2017.10.007

An estimate of lifetime noise exposure was used as the primary predictor of performance on a range of behavioral tasks: frequency and intensity difference limens, amplitude modulation detection, interaural phase discrimination, the digit triplet spee... Read More about Effects of noise exposure on young adults with normal audiograms II: Behavioral measures.

Bi-modal stimulation in the treatment of tinnitus: a study protocol for an exploratory trial to optimise stimulation parameters and patient subtyping (2017)
Journal Article
D’Arcy, S., Hamilton, C., Hughes, S., Hall, D. A., Vanneste, S., Langguth, B., & Conlon, B. (in press). Bi-modal stimulation in the treatment of tinnitus: a study protocol for an exploratory trial to optimise stimulation parameters and patient subtyping. BMJ Open, 7, Article e018465. https://doi.org/10.1136/bmjopen-2017-018465

Introduction: Tinnitus is the perception of sound in the absence of a corresponding external acoustic stimulus. Bi-modal neuromodulation is emerging as a promising treatment for this condition. The main objectives of this study are to investigate the... Read More about Bi-modal stimulation in the treatment of tinnitus: a study protocol for an exploratory trial to optimise stimulation parameters and patient subtyping.

Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank (2017)
Journal Article
Alfaro-Almagro, F., Jenkinson, M., Bangerter, N. K., Andersson, J. L., Griffanti, L., Douaud, G., …Smith, S. M. (2018). Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank. NeuroImage, 166, https://doi.org/10.1016/j.neuroimage.2017.10.034

UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound an... Read More about Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank.

A good practice guide for translating and adapting hearing-related questionnaires for different languages and cultures (2017)
Journal Article
Hall, D. A., Domingo, S. Z., Hamdache, L. Z., Manchaiah, V., Thammaiah, S., Evans, C., & Wong, L. (2018). A good practice guide for translating and adapting hearing-related questionnaires for different languages and cultures. International Journal of Audiology, 57(3), 161-175. https://doi.org/10.1080/14992027.2017.1393565

Objectives: To raise awareness and propose a good practice guide for translating and adapting any hearing-related questionnaire to be used for comparisons across populations divided by language or culture, and to encourage investigators to publish de... Read More about A good practice guide for translating and adapting hearing-related questionnaires for different languages and cultures.

Positive experiences related to living with tinnitus: a cross-sectional survey (2017)
Journal Article
Beukes, E. W., Manchaiah, V., Valien, T., Baguley, D. M., Allen, P. M., & Andersson, G. (2018). Positive experiences related to living with tinnitus: a cross-sectional survey. Clinical Otolaryngology, 43(2), 489-495. https://doi.org/10.1111/coa.13002

Objective: The aim of this study was to gain insights related to positive experiences reported by adults with tinnitus living in the United Kingdom.
Design: A cross-sectional survey design was used in a sample of adults with tinnitus who were intere... Read More about Positive experiences related to living with tinnitus: a cross-sectional survey.

Attitudes, risk behaviour and noise exposure among young adults with hearing problems: identifying a typology (2017)
Journal Article
Hunter, A. (in press). Attitudes, risk behaviour and noise exposure among young adults with hearing problems: identifying a typology. Seminars in Hearing, 38(4), https://doi.org/10.1055/s-0037-1606327

This study explored attitudes towards leisure noise and use of hearing protection, and perceived susceptibility to leisure noise damage in young adults with hearing problems. Twelve participants aged between 18 and 35 years took part in a semi-struct... Read More about Attitudes, risk behaviour and noise exposure among young adults with hearing problems: identifying a typology.

Clinical interventions for hyperacusis in adults: a scoping review to assess the current position and determine priorities for research (2017)
Journal Article
Fackrell, K., Potgieter, I., Shekhawat, G. S., Baguley, D. M., Sereda, M., & Hoare, D. J. (2017). Clinical interventions for hyperacusis in adults: a scoping review to assess the current position and determine priorities for research. BioMed Research International, 2017, Article 2723715. https://doi.org/10.1155/2017/2723715

Background. There is no universally accepted definition for hyperacusis, but in general it is characterised by decreased sound tolerance to ordinary environmental sounds. Despite hyperacusis being prevalent and having significant clinical implication... Read More about Clinical interventions for hyperacusis in adults: a scoping review to assess the current position and determine priorities for research.

Process evaluation of Internet-based cognitive behavioural therapy for adults with tinnitus in the context of a randomised control trial (2017)
Journal Article
Beukes, E. W., Manchaiah, V., Baguley, D. M., Allen, P. M., & Andersson, G. (2017). Process evaluation of Internet-based cognitive behavioural therapy for adults with tinnitus in the context of a randomised control trial. International Journal of Audiology, 57(2), 98-109. https://doi.org/10.1080/14992027.2017.1384858

Objective: The research objective was to identify processes that could either facilitate or hinder clinical implementation of an Internet-based cognitive behavioural therapy intervention for tinnitus in the UK. This was done by exploring the research... Read More about Process evaluation of Internet-based cognitive behavioural therapy for adults with tinnitus in the context of a randomised control trial.

A data-driven synthesis of research evidence for domains of hearing loss, as reported by adults with hearing loss and their communication partners (2017)
Journal Article
Vas, V., Akeroyd, M. A., & Hall, D. A. (in press). A data-driven synthesis of research evidence for domains of hearing loss, as reported by adults with hearing loss and their communication partners. Trends in Hearing, 21, https://doi.org/10.1177/2331216517734088

A number of assessment tools exist to evaluate the impact of hearing loss, with little consensus among researchers as to either preference or psychometric adequacy. The item content of hearing loss assessment tools should seek to capture the impact o... Read More about A data-driven synthesis of research evidence for domains of hearing loss, as reported by adults with hearing loss and their communication partners.

Seven-Tesla magnetization transfer imaging to detect multiple sclerosis white matter lesions (2017)
Journal Article
Chou, I.-J., Lim, S.-Y., Tanasescu, R., Al-Radaideh, A., Mougin, O. E., Tench, C. R., …Constantinescu, C. S. (in press). Seven-Tesla magnetization transfer imaging to detect multiple sclerosis white matter lesions. Journal of Neuroimaging, https://doi.org/10.1111/jon.12474

BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery (FLAIR) imaging at 3 Tesla (T) field strength is the most sensitive modality for detecting white matter lesions in multiple sclerosis. While 7T FLAIR is effective in detecting cortical lesio... Read More about Seven-Tesla magnetization transfer imaging to detect multiple sclerosis white matter lesions.