All Outputs (1073)

A Delphi survey to determine a definition and description of hyperacusis by clinician consensus (2020)
Journal Article
Adams, B., Sereda, M., Casey, A., Byrom, P., Stockdale, D., & Hoare, D. J. (2021). A Delphi survey to determine a definition and description of hyperacusis by clinician consensus. International Journal of Audiology, 60(8), 607-613. https://doi.org/10.1080/14992027.2020.1855370

Objective: There is currently no singularly accepted definition of hyperacusis. The aim of this study was to determine a definition and description of hyperacusis by clinician consensus. Design: A three-round Delphi survey involving hearing healthcar... Read More about A Delphi survey to determine a definition and description of hyperacusis by clinician consensus.

Natural history of tinnitus in adults: A cross-sectional and longitudinal analysis (2020)
Journal Article
Dawes, P., Newall, J., Stockdale, D., Baguley, D. M., & Dawes, P. (2020). Natural history of tinnitus in adults: A cross-sectional and longitudinal analysis. BMJ Open, 10(12), Article e041290. https://doi.org/10.1136/bmjopen-2020-041290

Objective To assess incidence and changes in tinnitus and bothersome tinnitus as well as associated risk factors in a large sample of UK adults. Design Prospective cohort study. Setting UK. Participants For cross-sectional analysis, a group of 168 34... Read More about Natural history of tinnitus in adults: A cross-sectional and longitudinal analysis.

Evaluating cortical responses to speech in children: A functional near-infrared spectroscopy (fNIRS) study (2020)
Journal Article
Lawrence, R., Wiggins, I., Hodgson, J., & Hartley, D. (2021). Evaluating cortical responses to speech in children: A functional near-infrared spectroscopy (fNIRS) study. Hearing Research, 401, Article 108155. https://doi.org/10.1016/j.heares.2020.108155

Functional neuroimaging of speech processing has both research and clinical potential. This work is facilitating an ever-increasing understanding of the complex neural mechanisms involved in the processing of speech. Neural correlates of speech under... Read More about Evaluating cortical responses to speech in children: A functional near-infrared spectroscopy (fNIRS) study.

PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis (2020)
Journal Article
Midgley, A., Barakat, D., Braitch, M., Nichols, C., Nebozhyn, M., Edwards, L. J., …Constantinescu, C. S. (2021). PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis. Immunobiology, 226(1), Article 152023. https://doi.org/10.1016/j.imbio.2020.152023

© 2020 Elsevier GmbH IL-23 is a potent stimulus for Th17 cells. These cells have a distinct developmental pathway from Th1 cells induced by IL-12 and are implicated in autoimmune and inflammatory disorders including multiple sclerosis (MS). TGF-β, IL... Read More about PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis.

Effects of Cognitive Behavioural Therapy on insomnia in adults with tinnitus: Systematic review and meta-analysis of randomised controlled trials (2020)
Journal Article
Curtis, F., Laparidou, D., Bridle, C., Law, G., Durrant, S., Rodriguez, A., …Siriwardena, A. N. (2021). Effects of Cognitive Behavioural Therapy on insomnia in adults with tinnitus: Systematic review and meta-analysis of randomised controlled trials. Sleep Medicine Reviews, 56, Article 101405. https://doi.org/10.1016/j.smrv.2020.101405

Insomnia is common in patients with tinnitus and negatively affects tinnitus symptoms and quality of life. This systematic review aimed to synthesise evidence of the effectiveness of cognitive behavioural therapy (CBT) based interventions on insomnia... Read More about Effects of Cognitive Behavioural Therapy on insomnia in adults with tinnitus: Systematic review and meta-analysis of randomised controlled trials.

Using Gap-Induced Inhibition of the Post-Auricular Muscle Response as an Objective Measure of Tinnitus in Humans (2020)
Journal Article
Wilson, C. A., Berger, J. I., De Boer, J., Sereda, M., Hall, D. A., & Wallace, M. N. (2020). Using Gap-Induced Inhibition of the Post-Auricular Muscle Response as an Objective Measure of Tinnitus in Humans. Acta Scientific Otolaryngology, 2(12), 40-52

A widely used method for detecting tinnitus in rodents is the gap pre-pulse inhibition of the acoustic startle (GPIAS). One variant uses the Preyer reflex to assess the startle response and a component of this can be measured as a small muscle pote... Read More about Using Gap-Induced Inhibition of the Post-Auricular Muscle Response as an Objective Measure of Tinnitus in Humans.

Corrigendum: Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis (2020)
Journal Article
Appleton, J. P., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., & Bath, P. M. (2020). Corrigendum: Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis. Frontiers in Neurology, 11, Article 625572. https://doi.org/10.3389/fneur.2020.625572

Joanna M. Wardlaw was not included as an author in the published article. The corrected Author Contributions and Funding statements appear below. AUTHOR CONTRIBUTIONS JA performed the literature search, pooled analyses, statistical analysis and inter... Read More about Corrigendum: Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis.

Seasonal patterns of incidence, demographic factors and microbiological profiles of infectious keratitis: the Nottingham Infectious Keratitis Study (2020)
Journal Article
Ting, D. S. J., Ho, C. S., Cairns, J., Gopal, B. P., Elsahn, A., Al-Aqaba, M., …Dua, H. S. (2021). Seasonal patterns of incidence, demographic factors and microbiological profiles of infectious keratitis: the Nottingham Infectious Keratitis Study. Eye, 35(9), 2543-2549. https://doi.org/10.1038/s41433-020-01272-5

Purpose: The purpose of this study is to examine the seasonal patterns of incidence, demographic factors and microbiological profiles of infectious keratitis (IK) in Nottingham, UK. Methods: A retrospective study of all patients who were diagnosed wi... Read More about Seasonal patterns of incidence, demographic factors and microbiological profiles of infectious keratitis: the Nottingham Infectious Keratitis Study.

The perceptual limitations of troubleshooting hearing-aids based on patients’ descriptions (2020)
Journal Article
Caswell-Midwinter, B., & Whitmer, W. M. (2021). The perceptual limitations of troubleshooting hearing-aids based on patients’ descriptions. International Journal of Audiology, 60(6), 427-437. https://doi.org/10.1080/14992027.2020.1839679

Objectives: Hearing-aid frequency-gain responses are routinely adjusted by clinicians to patient preferences and descriptions. This study measured the minimum gain adjustments required to elicit preferences, and the assignment of descriptors to gain... Read More about The perceptual limitations of troubleshooting hearing-aids based on patients’ descriptions.

Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): protocol for a phase II double blind randomised controlled feasibility trial (2020)
Journal Article
Desborough, M. J., Al-Shahi Salman, R., Stanworth, S. J., Havard, D., Brennan, P. M., Dineen, R. A., …DASH trial investigators. (2020). Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): protocol for a phase II double blind randomised controlled feasibility trial. BMJ Open, 10(11), Article e037555. https://doi.org/10.1136/bmjopen-2020-037555

Introduction Intracerebral haemorrhage (ICH) can be devastating and is a common cause of death and disability worldwide. Pre-ICH antiplatelet drug use is associated with a 27% relative increase in 1 month case fatality compared with patients not usin... Read More about Desmopressin for reversal of Antiplatelet drugs in Stroke due to Haemorrhage (DASH): protocol for a phase II double blind randomised controlled feasibility trial.

Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial (2020)
Journal Article
Beishon, L., Woodhouse, L. J., Bereczki, D., Christensen, H. K., Collins, R., Gommans, J., …Bath, P. M. (2021). Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial. Stroke and Vascular Neurology, 6(2), 180-186. https://doi.org/10.1136/svn-2020-000498

Introduction Nitrate-induced headache is common and may signify responsive cerebral vasculature. We assessed the relationship between nitrate headache and outcome in patients with acute stroke. Materials and methods Patients were those randomised to... Read More about Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial.

The feasibility of an m-health educational programme (m2Hear) to improve outcomes in first-time hearing aid users (2020)
Journal Article
Ferguson, M. A., Maidment, D. W., Gomez, R., Coulson, N., & Wharrad, H. (2020). The feasibility of an m-health educational programme (m2Hear) to improve outcomes in first-time hearing aid users. International Journal of Audiology, 60(Supplement 1), S30-S41. https://doi.org/10.1080/14992027.2020.1825839

© 2020 Crown Copyright. Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of British Society of Audiology, International Society of Audiology, and Nordic Audiological Society. Objective: To (i) assess the delivery, access... Read More about The feasibility of an m-health educational programme (m2Hear) to improve outcomes in first-time hearing aid users.

Pharyngeal electrical stimulation for neurogenic dysphagia following stroke, traumatic brain injury or other causes: Main results from the PHADER cohort study (2020)
Journal Article
Bath, P. M., Woodhouse, L. J., Suntrup-Krueger, S., Likar, R., Koestenberger, M., Warusevitane, A., …Dziewas, R. (2020). Pharyngeal electrical stimulation for neurogenic dysphagia following stroke, traumatic brain injury or other causes: Main results from the PHADER cohort study. eClinicalMedicine, 28, Article 100608. https://doi.org/10.1016/j.eclinm.2020.100608

Background: Neurogenic dysphagia is common and has no definitive treatment. We assessed whether pharyngeal electrical stimulation (PES) is associated with reduced dysphagia. Methods: The PHAryngeal electrical stimulation for treatment of neurogenic D... Read More about Pharyngeal electrical stimulation for neurogenic dysphagia following stroke, traumatic brain injury or other causes: Main results from the PHADER cohort study.

‘That’s just how I am’: a qualitative interview study to identify factors influencing engagement with a digital intervention for tinnitus self-management (2020)
Journal Article
Greenwell, K., Sereda, M., Coulson, N. S., Geraghty, A. W., Bradbury, K., & Hoare, D. J. (2020). ‘That’s just how I am’: a qualitative interview study to identify factors influencing engagement with a digital intervention for tinnitus self-management. British Journal of Health Psychology, https://doi.org/10.1111/bjhp.12486

© 2020 The Authors. British Journal of Health Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society Objectives: To explore users’ reactions to and expectations of the Tinnitus E-Programme 2.0, a digital cognitive... Read More about ‘That’s just how I am’: a qualitative interview study to identify factors influencing engagement with a digital intervention for tinnitus self-management.

Cerebrovascular accident and acute coronary syndrome and perioperative outcomes (CAPO) study protocol: a 10-year database linkage between Hospital Episode Statistics Admitted Patient Care, Myocardial Infarction National Audit Project and Office for National Statistics registries for time-dependent risk analysis of perioperative outcomes in English NHS hospitals (2020)
Journal Article
Luney, M., Lindsay, W., McKeever, T. M., & Moppett, I. K. (2020). Cerebrovascular accident and acute coronary syndrome and perioperative outcomes (CAPO) study protocol: a 10-year database linkage between Hospital Episode Statistics Admitted Patient Care, Myocardial Infarction National Audit Project and Office for National Statistics registries for time-dependent risk analysis of perioperative outcomes in English NHS hospitals. BMJ Open, 10(10), Article e037904. https://doi.org/10.1136/bmjopen-2020-037904

Introduction: An increasing number of people who have a history of acute coronary syndrome or cerebrovascular accident (termed cardiovascular events) are being considered for surgery. Up-to-date evidence of the impact of these prior events is needed... Read More about Cerebrovascular accident and acute coronary syndrome and perioperative outcomes (CAPO) study protocol: a 10-year database linkage between Hospital Episode Statistics Admitted Patient Care, Myocardial Infarction National Audit Project and Office for National Statistics registries for time-dependent risk analysis of perioperative outcomes in English NHS hospitals.

Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis (2020)
Journal Article
Appleton, J. P., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., & Bath, P. M. (2020). Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis. Frontiers in Neurology, 11, Article 584038. https://doi.org/10.3389/fneur.2020.584038

Background: Thrombolysis, with or without thrombectomy, for acute ischaemic stroke is associated with an increased risk of intracranial bleeding. We assessed whether treatment with glyceryl trinitrate (GTN), a nitric oxide donor, may influence the as... Read More about Intracranial Bleeding After Reperfusion Therapy in Acute Ischaemic Stroke Patients Randomized to Glyceryl Trinitrate vs. Control: An Individual Patient Data Meta-Analysis.

Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis (2020)
Journal Article
Meng, D., Welton, T., Elsarraj, A., Morgan, P. S., das Nair, R., Constantinescu, C. S., …Dineen, R. A. (2020). Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis. Human Brain Mapping, 42(2), 495-509. https://doi.org/10.1002/hbm.25239

Three decades ago a series of parallel circuits were described involving the frontal cortex and deep grey matter structures, with putative roles in control of motor and oculomotor function, cognition, behaviour and emotion. The circuit comprising the... Read More about Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT‐3 performance in multiple sclerosis.

Exploring the Factor Structure of the Glasgow Children’s Benefit Inventory: New Recommendations for Reporting Results (2020)
Journal Article
Kubba, H., & Whitmer, W. M. (2021). Exploring the Factor Structure of the Glasgow Children’s Benefit Inventory: New Recommendations for Reporting Results. Annals of Otology, Rhinology & Laryngology, 130(6), 614-622. https://doi.org/10.1177/0003489420965634

Objective
Patient-reported outcomes can be useful for reporting benefit from non-life-saving interventions, but often they report a single overall score, which means that much information on the specific areas of benefit is lost. Our aim was to per... Read More about Exploring the Factor Structure of the Glasgow Children’s Benefit Inventory: New Recommendations for Reporting Results.

Covalent attachment of active enzymes to upconversion phosphors allows ratiometric detection of substrates (2020)
Journal Article
Burgess, L., Wilson, H., Jones, A. R., Harvey, P., Natrajan, L., & Hay, S. (2020). Covalent attachment of active enzymes to upconversion phosphors allows ratiometric detection of substrates. Chemistry - A European Journal, 26(65), 14817-14822. https://doi.org/10.1002/chem.202001974

Upconverting phosphors (UCPs) convert multiple low energy photons into higher energy emission via the process of photon upconversion and offer an attractive alternative to organic fluorophores for use as luminescent probes. Here, UCPs were capped wit... Read More about Covalent attachment of active enzymes to upconversion phosphors allows ratiometric detection of substrates.

Conversation in small groups: Speaking and listening strategies depend on the complexities of the environment and group (2020)
Journal Article
Hadley, L. V., Whitmer, W. M., Brimijoin, W. O., & Naylor, G. (2021). Conversation in small groups: Speaking and listening strategies depend on the complexities of the environment and group. Psychonomic Bulletin and Review, 28(2), 632-640. https://doi.org/10.3758/s13423-020-01821-9

Many conversations in our day-to-day lives are held in noisy environments, impeding comprehension, and in groups, taxing auditory attention-switching processes. These situations are particularly challenging for older adults in cognitive and sensory d... Read More about Conversation in small groups: Speaking and listening strategies depend on the complexities of the environment and group.