All Outputs (171)

Developmental exposure to real-life environmental chemical mixture programs a testicular dysgenesis syndrome-like phenotype in prepubertal lambs (2022)
Journal Article
Elcombe, C. S., Monteiro, A., Elcombe, M. R., Ghasemzadeh-Hasankolaei, M., Sinclair, K. D., Lea, R., …Bellingham, M. (2022). Developmental exposure to real-life environmental chemical mixture programs a testicular dysgenesis syndrome-like phenotype in prepubertal lambs. Environmental Toxicology and Pharmacology, 94, Article 103913. https://doi.org/10.1016/j.etap.2022.103913

Current declines in male reproductive health may, in part, be driven by anthropogenic environmental chemical (EC) exposure. Using a biosolids treated pasture (BTP) sheep model, this study examined the effects of gestational exposure to a translationa... Read More about Developmental exposure to real-life environmental chemical mixture programs a testicular dysgenesis syndrome-like phenotype in prepubertal lambs.

Scoping review of end-of-life decision-making models used in dogs, cats and equids (2022)
Journal Article
Cameron, A., Pollock, K., Wilson, E., Burford, J., England, G., & Freeman, S. (2022). Scoping review of end-of-life decision-making models used in dogs, cats and equids. Veterinary Record, 191(4), Article e1730. https://doi.org/10.1002/vetr.1730

Background: End-of-life decisions for companion animals can be stressful for veterinarians and owners, and when delayed result in poor animal welfare. Delayed euthanasia has been identified as a particularly prominent issue for horses. This scoping r... Read More about Scoping review of end-of-life decision-making models used in dogs, cats and equids.

Analysis of phenotype-genotype associations using genomic informational field theory (GIFT) (2022)
Journal Article
Wattis, J. A., Bray, S. M., Kyratzi, P., & Rauch, C. (2022). Analysis of phenotype-genotype associations using genomic informational field theory (GIFT). Journal of Theoretical Biology, 548, Article 111198. https://doi.org/10.1016/j.jtbi.2022.111198

We show how field- and information theory can be used to quantify the relationship between genotype and phenotype in cases where phenotype is a continuous variable. Given a sample population of phenotype measurements, from various known genotypes, we... Read More about Analysis of phenotype-genotype associations using genomic informational field theory (GIFT).

Equine Stress: Neuroendocrine Physiology and Pathophysiology (2022)
Book Chapter
Kovac, M., Ippolitova, T. V., Pozyabin, S., Aliev, R., Lobanova, V., Drakul, N., & Rutland, C. S. (2022). Equine Stress: Neuroendocrine Physiology and Pathophysiology. In C. Rutland, & S. El-Gendy (Eds.), Updates on Veterinary Anatomy and Physiology (Working title). London: IntechOpen. https://doi.org/10.5772/intechopen.105045

Personality and predictability in farmed calves using movement and space-use behaviours quantified by ultra-wideband sensors (2022)
Journal Article
Occhiuto, F., Vázquez-Diosdado, J. A., Carslake, C., & Kaler, J. (2022). Personality and predictability in farmed calves using movement and space-use behaviours quantified by ultra-wideband sensors. Royal Society Open Science, 9(6), Article 212019. https://doi.org/10.1098/rsos.212019

Individuals within a population often show consistent between individual differences in their average behavioural expression (personality), and consistent differences in their within-individual variability of behaviour around the mean (predictability... Read More about Personality and predictability in farmed calves using movement and space-use behaviours quantified by ultra-wideband sensors.

N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals. (2022)
Journal Article
Sun, H., Deng, G., Sun, H., Song, J., Zhang, W., Li, H., …Liu, J. (2022). N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals. PNAS Nexus, 1(3), Article pgac085. https://doi.org/10.1093/pnasnexus/pgac085

Clade 2.3.4.4 avian H5Ny viruses, namely H5N2, H5N6, and H5N8, have exhibited unprecedented intercontinental spread in poultry. Among them, only H5N6 viruses are frequently reported to infect mammals and cause serious human infections. In this study,... Read More about N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals..

Lameness prevalence and management practices on Irish pasture-based dairy farms (2022)
Journal Article
Browne, N., Hudson, C. D., Crossley, R. E., Sugrue, K., Kennedy, E., Huxley, J. N., & Conneely, M. (2022). Lameness prevalence and management practices on Irish pasture-based dairy farms. Irish Veterinary Journal, 75, Article 14. https://doi.org/10.1186/s13620-022-00221-w

Background: Lameness is a painful disease, which negatively impacts dairy cow production and welfare. The aim of this observational study was to determine herd lameness prevalence, describe current lameness management practices and identify the prese... Read More about Lameness prevalence and management practices on Irish pasture-based dairy farms.

“We’re gonna end up scared to do anything”: a qualitative exploration of how complaints are experienced by UK veterinary practitioners (2022)
Journal Article
Gibson, J., White, K., Mossop, L., Oxtoby, C., & Brennan, M. (2022). “We’re gonna end up scared to do anything”: a qualitative exploration of how complaints are experienced by UK veterinary practitioners. Veterinary Record, 191(4), Article e1737. https://doi.org/10.1002/vetr.1737

Background: UK veterinary practitioners are reported to be fearful of client complaints but their experiences have not been formally captured. Understanding how complaints impact veterinary practitioners is key to mitigating detrimental consequences.... Read More about “We’re gonna end up scared to do anything”: a qualitative exploration of how complaints are experienced by UK veterinary practitioners.

Holistic Fault Detection and Diagnosis System in Imbalanced, Scarce, Multi-Domain (ISMD) Data Setting for Component-Level Prognostics and Health Management (PHM) (2022)
Journal Article
Rohan, A. (2022). Holistic Fault Detection and Diagnosis System in Imbalanced, Scarce, Multi-Domain (ISMD) Data Setting for Component-Level Prognostics and Health Management (PHM). Mathematics, 10(12), Article 2031. https://doi.org/10.3390/math10122031

In the current Industry 4.0 revolution, prognostics and health management (PHM) is an emerging field of research. The difficulty of obtaining data from electromechanical systems in an industrial setting increases proportionally with the scale and acc... Read More about Holistic Fault Detection and Diagnosis System in Imbalanced, Scarce, Multi-Domain (ISMD) Data Setting for Component-Level Prognostics and Health Management (PHM).

Use of Non-Steroidal Anti-Inflammatory Drugs and Attitudes to Pain in Pasture-Based Dairy Cows: A Comparative Study of Farmers and Veterinarians (2022)
Journal Article
Browne, N., Conneely, M., & Hudson, C. (2022). Use of Non-Steroidal Anti-Inflammatory Drugs and Attitudes to Pain in Pasture-Based Dairy Cows: A Comparative Study of Farmers and Veterinarians. Frontiers in Veterinary Science, 9, Article 912564. https://doi.org/10.3389/fvets.2022.912564

Pain is a significant welfare concern within the dairy industry. Recognizing and managing pain are important factors for safeguarding animal welfare. A questionnaire was sent via post to Irish dairy farmers and large animal veterinarians to assess at... Read More about Use of Non-Steroidal Anti-Inflammatory Drugs and Attitudes to Pain in Pasture-Based Dairy Cows: A Comparative Study of Farmers and Veterinarians.

Differences in composition of interdigital skin microbiota predict sheep and feet that develop footrot (2022)
Journal Article
Clifton, R., Monaghan, E. M., Green, M. J., Purdy, K. J., & Green, L. E. (2022). Differences in composition of interdigital skin microbiota predict sheep and feet that develop footrot. Scientific Reports, 12, Article 8931. https://doi.org/10.1038/s41598-022-12772-7

Footrot has a major impact on health and productivity of sheep worldwide. The current paradigm for footrot pathogenesis is that physical damage to the interdigital skin (IDS) facilitates invasion of the essential pathogen Dichelobacter nodosus. The c... Read More about Differences in composition of interdigital skin microbiota predict sheep and feet that develop footrot.

Human pediculosis, a global public health problem (2022)
Journal Article
Fu, Y., Yao, C., Deng, Y., Elsheikha, H. M., Shao, R., Zhu, X., & Liu, G. (2022). Human pediculosis, a global public health problem. Infectious Diseases of Poverty, 11(1), Article 58. https://doi.org/10.1186/s40249-022-00986-w

Background: Human pediculosis is caused by hematophagous lice, which are transmitted between individuals via direct and/or indirect contact. Despite the public health importance of louse infestation, information concerning the global burden of pedicu... Read More about Human pediculosis, a global public health problem.

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles (2022)
Journal Article
Bhome, R., Emaduddin, M., James, V., House, L. M., Thirdborough, S. M., Mellone, M., …Sayan, A. E. (2022). Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles. Journal of Extracellular Vesicles, 11(5), Article e12226. https://doi.org/10.1002/jev2.12226

Colorectal cancer (CRC) with a mesenchymal gene expression signature has the greatest propensity for distant metastasis and is characterised by the accumulation of cancer-associated fibroblasts in the stroma. We investigated whether the epithelial to... Read More about Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles.

Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial (2022)
Journal Article
Wilson, J., Green, M., Randall, L., Rutland, C., Bell, N., Hemingway-Arnold, H., …Huxley, J. (2022). Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial. Journal of Dairy Science, 105(7), 6041-6054. https://doi.org/10.3168/jds.2021-21329

Claw horn lesions (CHL) are reported as the most common cause of lameness in intensive dairy systems. Despite their prevalence, the underlying pathological mechanisms and preventive strategies for CHL remain poorly understood. Recent advances have po... Read More about Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial.

Development and the Art of Nutritional Maintenance (2022)
Journal Article
Gardner, D. S., & Gray, C. (2022). Development and the Art of Nutritional Maintenance. British Journal of Nutrition, 1-24. https://doi.org/10.1017/S0007114522001490

Development from early conceptus to a complex, multi-cellular organism is a highly ordered process that is dependent on an adequate supply of nutrients. During this process, the pattern of organ growth is robust, driven by a genetic blueprint and mat... Read More about Development and the Art of Nutritional Maintenance.

Human health implications from consuming eggs produced near a derelict metalliferous mine: a case study (2022)
Journal Article
Sartorius, A., Johnson, M., Young, S., Bennett, M., Baiker, K., Edwards, P., & Yon, L. (2022). Human health implications from consuming eggs produced near a derelict metalliferous mine: a case study. Food Additives and Contaminants: Part A: Chemistry, Analysis, Control, Exposure and Risk Assessment, 39(6), 1074-1085. https://doi.org/10.1080/19440049.2022.2062059

Lead pollution from metalliferous mines can have major environmental and health effects long after the mines have closed. Animals living near derelict mine sites can inadvertently ingest lead-contaminated soils, causing them to accumulate lead and po... Read More about Human health implications from consuming eggs produced near a derelict metalliferous mine: a case study.

Prophylactic Delivery of a Bacteriophage Cocktail in Feed Significantly Reduces Salmonella Colonization in Pigs (2022)
Journal Article
Thanki, A. M., Mignard, G., Atterbury, R. J., Barrow, P., Millard, A. D., & Clokie, M. R. J. (2022). Prophylactic Delivery of a Bacteriophage Cocktail in Feed Significantly Reduces Salmonella Colonization in Pigs. Microbiology Spectrum, 10(3), e0042222. https://doi.org/10.1128/spectrum.00422-22

Nontyphoidal Salmonella spp. are a leading cause of human food poisoning and can be transmitted to humans via consuming contaminated pork. To reduce Salmonella spread to the human food chain, bacteriophage (phage) therapy could be used to reduce bact... Read More about Prophylactic Delivery of a Bacteriophage Cocktail in Feed Significantly Reduces Salmonella Colonization in Pigs.

Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds (2022)
Journal Article
Nie, L.-B., Liang, Q.-L., Wang, M., Du, R., Zhang, M.-Y., Elsheikha, H. M., & Zhu, X.-Q. (2022). Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds. PLoS Neglected Tropical Diseases, 16(5), Article e0010431. https://doi.org/10.1371/journal.pntd.0010431

Lysine malonylation is a post-translational modification (PTM), which regulates many cellular processes. Limited information is available about the level of lysine malonylation variations between Toxoplasma gondii strains of distinct genetic lineages... Read More about Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds.

Identifying associations between management practices and antimicrobial resistances of sentinel bacteria recovered from bulk tank milk on dairy farms (2022)
Journal Article
McLaughlin, D., Bradley, A., Dottorini, T., Giebel, K., Leach, K., Hyde, R., & Green, M. (2022). Identifying associations between management practices and antimicrobial resistances of sentinel bacteria recovered from bulk tank milk on dairy farms. Preventive Veterinary Medicine, 204, Article 105666. https://doi.org/10.1016/j.prevetmed.2022.105666

There is increasing emphasis on the need to reduce antimicrobial use (AMU) on dairy farms to reduce the emergence of resistant bacteria which could compromise animal health and impact human medicine. In addition to AMU, the role of farm management is... Read More about Identifying associations between management practices and antimicrobial resistances of sentinel bacteria recovered from bulk tank milk on dairy farms.

Genetic Therapy in Veterinary Medicine (2022)
Journal Article
Zakirova, E. Y., Malanyeva, A. G., Rutland, C. S., & Aimaletdinov, A. M. (2022). Genetic Therapy in Veterinary Medicine. BioNanoScience, https://doi.org/10.1007/s12668-022-00986-y

Gene therapy focuses on the genetic modification of cells, to produce a therapeutic effect or for the treatment of disease, by repairing or reconstructing defective genetic material. The development of genetic engineering and biotechnology makes it p... Read More about Genetic Therapy in Veterinary Medicine.