All Outputs (3)

A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA (2011)
Journal Article
Kruse, S., Zhong, S., Bodi, Z., Button, J., Alcocer, M. J., Hayes, C. J., & Fray, R. (2011). A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA. Scientific Reports, 1, Article 126. https://doi.org/10.1038/srep00126

A method is described for the detection of certain nucleotide modifications adjacent to the 5' 7-methyl guanosine cap of mRNAs from individual genes. The method quantitatively measures the relative abundance of 2'-O-methyl and N 6.

Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants (2011)
Journal Article
Gibbs, D. J., Lee, S. C., Md Isa, N., Gramuglia, S., Fukao, T., Bassel, G. W., …Holdsworth, M. J. (2011). Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants. Nature, 479(7373), 415-418. https://doi.org/10.1038/nature10534

Plants and animals are obligate aerobes, requiring oxygen for mitochondrial respiration and energy production. In plants, an unanticipated decline in oxygen availability (hypoxia), as caused by roots becoming waterlogged or foliage submergence, trigg... Read More about Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants.

Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes (2011)
Journal Article
Graham, N. S., May, S. T., Daniel, Z. C., Emmerson, Z. F., Brameld, J. M., & Parr, T. (2011). Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes. Animal, 5(6), 861-866. https://doi.org/10.1017/S1751731110002533

Affymetrix GeneChip microarrays are a powerful tool to study global gene expression profiles and have been used on many species. However, no sheep-specific Affymetrix GeneChip is currently available and the bovine array is fairly limited in its cover... Read More about Use of the Affymetrix human GeneChip array and genomic DNA hybridisation probe selection to study ovine transcriptomes.