A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA

Kruse, Susanne; Zhong, Silin; Bodi, Zsuzsanna; Button, James; Alcocer, Marcos J.C.; Hayes, Christopher J.; Fray, Rupert

Abstract

A method is described for the detection of certain nucleotide modifications adjacent to the 5' 7-methyl guanosine cap of mRNAs from individual genes. The method quantitatively measures the relative abundance of 2'-O-methyl and N 6.

Citation

Kruse, S., Zhong, S., Bodi, Z., Button, J., Alcocer, M. J., Hayes, C. J., & Fray, R. (2011). A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA. Scientific Reports, 1, Article 126. https://doi.org/10.1038/srep00126

• Journal Article Type: Article
• Acceptance Date: Oct 7, 2011
• Online Publication Date: Oct 24, 2011
• Publication Date: Dec 1, 2011
• Deposit Date: Aug 11, 2020
• Publicly Available Date: Sep 21, 2020
• Journal: Scientific Reports
• Electronic ISSN: 2045-2322
• Publisher: Nature Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 1
• Article Number: 126
• DOI: https://doi.org/10.1038/srep00126
• Public URL: https://nottingham-repository.worktribe.com/output/3143640
• Publisher URL: https://www.nature.com/articles/srep00126