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Can selenium deficiency in Malawi be alleviated through consumption of agro-biofortified maize flour? Study protocol for a randomised, double-blind, controlled trial (2019)
Journal Article
Joy, E. J., Kalimbira, A. A., Gashu, D., Ferguson, E. L., Sturgess, J., Dangour, A. D., …Allen, E. (2019). Can selenium deficiency in Malawi be alleviated through consumption of agro-biofortified maize flour? Study protocol for a randomised, double-blind, controlled trial. Trials, 20(1), Article 795. https://doi.org/10.1186/s13063-019-3894-2

© 2019 The Author(s). Background: Micronutrient deficiencies including selenium (Se) are widespread in Malawi and potentially underlie a substantial disease burden, particularly among poorer and marginalised populations. Concentrations of Se in stapl... Read More about Can selenium deficiency in Malawi be alleviated through consumption of agro-biofortified maize flour? Study protocol for a randomised, double-blind, controlled trial.

Effects of dietary vegetable oils on mammary lipid-related genes in holstein dairy cows (2019)
Journal Article
Vargas-Bello-pérez, E., Geldsetzer-Mendoza, C., Cancino-Padilla, N., Morales, M. S., Leskinen, H., Garnsworthy, P. C., …Romero, J. (2020). Effects of dietary vegetable oils on mammary lipid-related genes in holstein dairy cows. Animals, 10(1), Article 57. https://doi.org/10.3390/ani10010057

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This study analyzed effects of vegetable oils fed to dairy cows on abundance of genes related to lipid metabolism in milk somatic cells (MSC). During 63 days, 15 cows were allocated to 3 treat... Read More about Effects of dietary vegetable oils on mammary lipid-related genes in holstein dairy cows.

Acute thiamethoxam toxicity in honeybees is not enhanced by common fungicide and herbicide and lacks stress-induced changes in mRNA splicing (2019)
Journal Article
Decio, P., Ustaoglu, P., Roat, T. C., Malaspina, O., Devaud, J.-M., Stöger, R., & Soller, M. (2019). Acute thiamethoxam toxicity in honeybees is not enhanced by common fungicide and herbicide and lacks stress-induced changes in mRNA splicing. Scientific Reports, 9(1), Article 19196. https://doi.org/10.1038/s41598-019-55534-8

Securing food supply for a growing population is a major challenge and heavily relies on the use of agrochemicals to maximize crop yield. It is increasingly recognized, that some neonicotinoid insecticides have a negative impact on non-target organis... Read More about Acute thiamethoxam toxicity in honeybees is not enhanced by common fungicide and herbicide and lacks stress-induced changes in mRNA splicing.

Genome-wide association studies for methane production in dairy cattle (2019)
Journal Article
Calderón-Chagoya, R., Hernandez-Medrano, J. H., Ruiz-López, F. J., Garcia-Ruiz, A., Vega-Murillo, V. E., Montano-Bermudez, M., …Román-Ponce, S. I. (2019). Genome-wide association studies for methane production in dairy cattle. Genes, 10(12), Article 995. https://doi.org/10.3390/genes10120995

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Genomic selection has been proposed for the mitigation of methane (CH4) emissions by cattle because there is considerable variability in CH4 emissions between individuals fed on the same diet.... Read More about Genome-wide association studies for methane production in dairy cattle.

Comprehensive and quantitative profiling of B vitamins and related compounds in the mammalian liver (2019)
Journal Article
Xu, J., Clare, C. E., Brassington, A. H., Sinclair, K., & Barrett, D. (2020). Comprehensive and quantitative profiling of B vitamins and related compounds in the mammalian liver. Journal of Chromatography B, 1136, Article 121884. https://doi.org/10.1016/j.jchromb.2019.121884

A method for the simultaneous quantification of B vitamins and related amines in one-carbon (1C) metabolism would benefit the study of diet and genetic/epigenetic regulation of mammalian development and health. We present a validated method for the s... Read More about Comprehensive and quantitative profiling of B vitamins and related compounds in the mammalian liver.

Regulation of Cell Fate Decisions in Early Mammalian Embryos (2019)
Journal Article
Alberio, R. (2020). Regulation of Cell Fate Decisions in Early Mammalian Embryos. Annual Review of Animal Biosciences, 8(1), 377-393. https://doi.org/10.1146/annurev-animal-021419-083841

Early embryogenesis is characterized by the segregation of cell lineages that fulfill critical roles in the establishment of pregnancy and development of the fetus. The formation of the blastocyst marks the emergence of extraembryonic precursors, nee... Read More about Regulation of Cell Fate Decisions in Early Mammalian Embryos.

The neurobiological basis of sex differences in learned fear and its inhibition (2019)
Journal Article
Day, H. L., & Stevenson, C. W. (2020). The neurobiological basis of sex differences in learned fear and its inhibition. European Journal of Neuroscience, 52(1), 2466-2486. https://doi.org/10.1111/ejn.14602

Learning that certain cues or environments predict threat enhances survival by promoting appropriate fear and the resulting defensive responses. Adapting to changing stimulus contingencies by learning that such cues no longer predict threat, or disti... Read More about The neurobiological basis of sex differences in learned fear and its inhibition.

Comparison of Methods to Measure Methane for Use in Genetic Evaluation of Dairy Cattle (2019)
Journal Article
Garnsworthy, P. C., Difford, G. F., Bell, M. J., Bayat, A. R., Huhtanen, P., Kuhla, B., …Yan, T. (2019). Comparison of Methods to Measure Methane for Use in Genetic Evaluation of Dairy Cattle. Animals, 9(10), Article 837. https://doi.org/10.3390/ani9100837

Partners in Expert Working Group WG2 of the COST Action METHAGENE (www.methagene.eu) have used several methods for measuring methane output by individual dairy cattle under various environmental conditions. Methods included respiration chambers, the... Read More about Comparison of Methods to Measure Methane for Use in Genetic Evaluation of Dairy Cattle.

Effect of Feeding Cows with Unsaturated Fatty Acid Sources on Milk Production, Milk Composition, Milk Fatty Acid Profile, and Physicochemical and Sensory Characteristics of Ice Cream (2019)
Journal Article
Vargas-Bello-Pérez, E., Cancino-Padilla, N., Geldsetzer-Mendoza, C., Vyhmeister, S., Morales, M. S., Leskinen, H., …Ibáñez, R. A. (2019). Effect of Feeding Cows with Unsaturated Fatty Acid Sources on Milk Production, Milk Composition, Milk Fatty Acid Profile, and Physicochemical and Sensory Characteristics of Ice Cream. Animals, 9(8), 1-13. https://doi.org/10.3390/ani9080568

Simple Summary: The objective of this study was to evaluate the effects of supplementation of dairy cows' diets with different fatty acid (FA) sources on milk production, milk composition, milk fatty acid profile, and physicochemical and sensory char... Read More about Effect of Feeding Cows with Unsaturated Fatty Acid Sources on Milk Production, Milk Composition, Milk Fatty Acid Profile, and Physicochemical and Sensory Characteristics of Ice Cream.

A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos (2019)
Journal Article
Canizo, J. R., Ynsaurralde Rivolta, A. E., Vazquez Echegaray, C., Suvá, M., Alberio, V., Aller, J. F., …Alberio, R. (2019). A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos. BMC Developmental Biology, 19(1), 1-13. https://doi.org/10.1186/s12861-019-0193-9

Background
The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been partially studied, and evidence s... Read More about A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos.

A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions (2019)
Journal Article
Wallace, R. J., Sasson, G., Garnsworthy, P. C., Tapio, I., Gregson, E., Bani, P., …Mizrahi, I. (2019). A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions. Science Advances, 5(7), Article eaav8391. https://doi.org/10.1126/sciadv.aav8391

A 1000-cow study across four European countries was undertaken to understand to what extent ruminant microbiomes can be controlled by the host animal and to identify characteristics of the host rumen microbiome axis that determine productivity and me... Read More about A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions.

Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows (2019)
Journal Article
Breider, I., Wall, E., & Garnsworthy, P. (2019). Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows. Journal of Dairy Science, 102(8), 7277-7281. https://doi.org/10.3168/jds.2018-15909

Greenhouse gases originating from the dairy sector, including methane (CH 4), contribute to global warming. A possible strategy to reduce CH 4 production is to use genetic selection. This requires genetic parameters for CH 4 production and correlatio... Read More about Short communication: Heritability of methane production and genetic correlations with milk yield and body weight in Holstein-Friesian dairy cows.

Optimisation and investigations into the effect of a phosphorylated tocopherol mixture on growth performance, meat quality and plasma inflammatory biomarkers in broilers (2019)
Journal Article
Akter, Y., Libinaki, R., Hutchison, C., Hopcroft, R., Edwards, A., Edwards, M., & O’Shea, C. (2019). Optimisation and investigations into the effect of a phosphorylated tocopherol mixture on growth performance, meat quality and plasma inflammatory biomarkers in broilers. Animal Feed Science and Technology, 253, 181-190. https://doi.org/10.1016/j.anifeedsci.2019.04.017

© 2019 This study investigated the effect of a novel phosphorylated tocopherol mixture (TPM) on the growth performance, nutrient digestibility, meat quality, and blood plasma markers of inflammation in broilers reared in normal temperatures (NT) or c... Read More about Optimisation and investigations into the effect of a phosphorylated tocopherol mixture on growth performance, meat quality and plasma inflammatory biomarkers in broilers.

The overlooked cohort? – Improving the taught postgraduate student experience in higher education (2019)
Journal Article
Coneyworth, L., Jessop, R., Maden, P., & White, G. (2020). The overlooked cohort? – Improving the taught postgraduate student experience in higher education. Innovations in Education and Teaching International, 57(3), 262-273. https://doi.org/10.1080/14703297.2019.1617184

Taught postgraduate students in the UK have a limited timeframe for study, with most full-time courses requiring intense scholarship, typically over a 12-month period. Many of these students face challenges and concerns with the transition from under... Read More about The overlooked cohort? – Improving the taught postgraduate student experience in higher education.

Cannabinoid regulation of fear and anxiety: an update (2019)
Journal Article
Papagianni, E. P., & Stevenson, C. W. (2019). Cannabinoid regulation of fear and anxiety: an update. Current Psychiatry Reports, 21(6), 1-10. https://doi.org/10.1007/s11920-019-1026-z

Purpose of Review
Anxiety- and trauma-related disorders are prevalent and debilitating mental illnesses associated with a significant socioeconomic burden. Current treatment approaches often have inadequate therapeutic responses, leading to symptom... Read More about Cannabinoid regulation of fear and anxiety: an update.

Effects of distillers dried grains with solubles on amino acid digestibility, growth performance, and carcass characteristics of growing pigs (2019)
Journal Article
Curry, S. M., Blavi, L., Wiseman, J., & Stein, H. H. (2019). Effects of distillers dried grains with solubles on amino acid digestibility, growth performance, and carcass characteristics of growing pigs. Translational Animal Science, 3(2), Article txz005. https://doi.org/10.1093/tas/txz005

Two experiments were conducted to compare the standardized ileal digestibility (SID) of AA by growing pigs in European distillers dried grains with solubles (DDGS) produced from wheat, maize, or wheat–maize mixtures and to test the effect of increasi... Read More about Effects of distillers dried grains with solubles on amino acid digestibility, growth performance, and carcass characteristics of growing pigs.

Clinical measurements performed during alfaxalone total intravenous anaesthesia for radiography and neurophysiological investigations in dogs (2019)
Journal Article
Harris, J. R., Goff, M., Jenkins, H., Harris, J., Knowles, T. B., Lascelles, B. D., …Murrell, J. C. (2019). Clinical measurements performed during alfaxalone total intravenous anaesthesia for radiography and neurophysiological investigations in dogs. Veterinary Anaesthesia and Analgesia, 46(4), 483-487. https://doi.org/10.1016/j.vaa.2018.11.010

Objective: To describe clinically relevant, physiological measurements collected during a 3- hour duration alfaxalone total intravenous anaesthesia.
Study design: Case series.
Animals: A total of 112 client-owned middle aged or older dogs.
Methods... Read More about Clinical measurements performed during alfaxalone total intravenous anaesthesia for radiography and neurophysiological investigations in dogs.

Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning (2019)
Journal Article
Stubbendorff, C., Hale, E., Cassaday, H. J., Bast, T., & Stevenson, C. W. (2019). Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning. Psychopharmacology, 236(6), 1771-1782. https://doi.org/10.1007/s00213-018-5162-7

Rationale

Dopamine D1 receptor (D1R) signalling is involved in contextual fear conditioning. The D1R antagonist SCH23390 impairs the acquisition of contextual fear when administered systemically or infused locally into the dorsal hippocampus or ba... Read More about Dopamine D1-like receptors in the dorsomedial prefrontal cortex regulate contextual fear conditioning.

Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves (2018)
Journal Article
Handyside, A. H., Turner, K. J., Silvestri, G., Black, D. H., Dobson, G., Smith, C., …Griffin, D. K. (2019). Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves. Theriogenology, 125, 249-258. https://doi.org/10.1016/j.theriogenology.2018.11.014

© 2018 The Authors In cattle breeding, the development of genomic selection strategies based on single nucleotide polymorphism (SNP) interrogation has led to improved rates of genetic gain. Additionally, the application of genomic selection to in-vit... Read More about Karyomapping for simultaneous genomic evaluation and aneuploidy screening of preimplantation bovine embryos: The first live-born calves.