Einar Vargas-Bello-p�rez
Effects of dietary vegetable oils on mammary lipid-related genes in holstein dairy cows
Vargas-Bello-p�rez, Einar; Geldsetzer-Mendoza, Carolina; Cancino-Padilla, Nathaly; Morales, Mar�a Sol; Leskinen, Heidi; Garnsworthy, Philip C.; Loor, Juan J.; Romero, Jaime
Authors
Carolina Geldsetzer-Mendoza
Nathaly Cancino-Padilla
Mar�a Sol Morales
Heidi Leskinen
Philip C. Garnsworthy
Juan J. Loor
Jaime Romero
Abstract
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This study analyzed effects of vegetable oils fed to dairy cows on abundance of genes related to lipid metabolism in milk somatic cells (MSC). During 63 days, 15 cows were allocated to 3 treatments: a control diet with no added lipid the same diet supplemented with olive oil (OO, 30 g/kg DM) or hydrogenated vegetable oil (HVO, 30 g/kg DM). On days 21, 42 and 63, MSC were obtained from all cows. Relative abundance of genes involved in lipid metabolism in MSC from cows fed control on days 42 and 63 was compared with relative abundance at day 21 to evaluate fold-changes. Those genes without changes over the time were selected to analyze effects of OO and HVO. Compared with control, on day 42, PLIN2 and THRSP were upregulated by OO. Compared with control, on day 21, HVO up regulated ACACA, down regulated FABP3, and on day 63 THRSP and FABP4 were down regulated. Dietary oil supplementation (3% DM) had a modest nutrigenomic effect on different biological functions such as acetate and FA activation and intra-cellular transport, lipid droplet formation, and transcription regulation in MSC.
Citation
Vargas-Bello-pérez, E., Geldsetzer-Mendoza, C., Cancino-Padilla, N., Morales, M. S., Leskinen, H., Garnsworthy, P. C., …Romero, J. (2020). Effects of dietary vegetable oils on mammary lipid-related genes in holstein dairy cows. Animals, 10(1), Article 57. https://doi.org/10.3390/ani10010057
Journal Article Type | Article |
---|---|
Acceptance Date | Dec 23, 2019 |
Online Publication Date | Dec 27, 2019 |
Publication Date | Jan 1, 2020 |
Deposit Date | Feb 11, 2020 |
Publicly Available Date | Mar 28, 2024 |
Journal | Animals |
Electronic ISSN | 2076-2615 |
Publisher | MDPI |
Peer Reviewed | Peer Reviewed |
Volume | 10 |
Issue | 1 |
Article Number | 57 |
DOI | https://doi.org/10.3390/ani10010057 |
Public URL | https://nottingham-repository.worktribe.com/output/3637527 |
Publisher URL | https://www.mdpi.com/2076-2615/10/1/57 |
Files
animals-10-00057
(275 Kb)
PDF
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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