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Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication (2025)
Journal Article
Romero, M., Luckett, J., Dubern, J.-F., Figueredo, G. P., Carabelli, A. M., Scurr, D. J., Hook, A. L., Kammerling, L., Da Silva, A. C., Xue, X., Blackburn, C., Carlier, A., Vasilevich, A., Sudarsanam, P. K., Vermeulen, S., Winkler, D. A., Ghaemmaghami, A. M., De Boer, J., Alexander, M. R., & Williams, P. (2025). Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication. Nature Communications, 16, Article 5295. https://doi.org/10.1038/s41467-025-60567-x

Bio-instructive materials that intrinsically inhibit biofilm formation have significant anti-biofouling potential in industrial and healthcare settings. Since bacterial surface attachment is sensitive to surface topography, we experimentally surveyed... Read More about Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication.