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Pairwise Accelerated Failure Time Regression Models for Infectious Disease Transmission in Close‐Contact Groups With External Sources of Infection (2024)
Journal Article
Sharker, Y., Diallo, Z., KhudaBukhsh, W. R., & Kenah, E. (2024). Pairwise Accelerated Failure Time Regression Models for Infectious Disease Transmission in Close‐Contact Groups With External Sources of Infection. Statistics in Medicine, https://doi.org/10.1002/sim.10226

Many important questions in infectious disease epidemiology involve associations between covariates (e.g., age or vaccination status) and infectiousness or susceptibility. Because disease transmission produces dependent outcomes, these questions are... Read More about Pairwise Accelerated Failure Time Regression Models for Infectious Disease Transmission in Close‐Contact Groups With External Sources of Infection.

SIR epidemics in populations with large sub-communities (2024)
Journal Article
Ball, F., Sirl, D., & Trapman, P. (2024). SIR epidemics in populations with large sub-communities. Annals of Applied Probability, 34(5), 4408–4454. https://doi.org/10.1214/24-aap2070

We investigate final outcome properties of an SIR (susceptible → in-fective → recovered) epidemic model defined on a population of large sub-communities in which there is stronger disease transmission within the communities than between them. Our ana... Read More about SIR epidemics in populations with large sub-communities.

Object oriented data analysis of surface motion time series in peatland landscapes (2024)
Journal Article
Mitchell, E., Ian, D., Christopher, F., Roxanne, A., Bradley, A., David, L., & Andrew, S. (in press). Object oriented data analysis of surface motion time series in peatland landscapes. Journal of the Royal Statistical Society: Series C,

Peatlands account for 10% of UK land area, 80% of which are degraded to some degree, emitting carbon at a similar magnitude to oil refineries or landfill sites. A lack of tools for rapid and reliable assessment of peatland condition has limited monit... Read More about Object oriented data analysis of surface motion time series in peatland landscapes.

EXPRESS: Stratified Distributional Analysis -- a Novel Perspective on RT Distributions (2024)
Journal Article
Thul, R., Marsh, J., Dijkstra, T., & Conklin, K. (2024). EXPRESS: Stratified Distributional Analysis -- a Novel Perspective on RT Distributions. Quarterly Journal of Experimental Psychology, https://doi.org/10.1177/17470218241288516

Response times and their distributions serve as a powerful lens into cognitive processes. We present a novel statistical methodology called Stratified Distributional Analysis (SDA) to quantitatively assess how key determinants of response times (word... Read More about EXPRESS: Stratified Distributional Analysis -- a Novel Perspective on RT Distributions.

Comparative judgement modeling to map forced marriage at local levels (2024)
Journal Article
Seymour, R., Nyarko-Agyei, A., Mccabe, H., Severn, K., Sirl, D., Kypraios, T., & Taylor, A. (in press). Comparative judgement modeling to map forced marriage at local levels. Annals of Applied Statistics,

Forcing someone into marriage against their will is a violation of their human rights. In 2021, the county of Nottinghamshire, UK, launched a strategy to tackle forced marriage and violence against women and girls. We set out to map the risk of force... Read More about Comparative judgement modeling to map forced marriage at local levels.

Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping. (2024)
Journal Article
Kyratzi, P., Matika, O., Brassington, A. H., Clare, C. E., Xu, J., Barrett, D. A., Emes, R. D., Archibald, A. L., Paldi, A., Sinclair, K. D., Wattis, J., & Rauch, C. (in press). Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping. Physiological Genomics, https://doi.org/10.1152/physiolgenomics.00049.2024

Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using averages and varia... Read More about Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping..

A Shape-Newton method for free-boundary problems subject to the Bernoulli boundary condition (2024)
Journal Article
Fan, Y., Billingham, J., & van der Zee, K. (in press). A Shape-Newton method for free-boundary problems subject to the Bernoulli boundary condition. SIAM Journal on Scientific Computing,


We develop a shape-Newton method for solving generic free-boundary problems where one of the free-boundary conditions is governed by the nonlinear Bernoulli equation. The method is a Newton-like scheme that employs shape derivatives of the governin... Read More about A Shape-Newton method for free-boundary problems subject to the Bernoulli boundary condition.

Topo-Geometric Analysis of Variability in Point Clouds using Persistence Landscapes (2024)
Journal Article
Matuk, J., Kurtek, S., & Bharath, K. (in press). Topo-Geometric Analysis of Variability in Point Clouds using Persistence Landscapes. IEEE Transactions on Pattern Analysis and Machine Intelligence,

Topological data analysis provides a set of tools to uncover low-dimensional structure in noisy point clouds. Prominent amongst the tools is persistence homology, which summarizes birth-death times of homological features using data objects known as... Read More about Topo-Geometric Analysis of Variability in Point Clouds using Persistence Landscapes.

Optimising experimental designs for model selection of ion channel drug binding mechanisms (2024)
Preprint / Working Paper
Patten-Elliott, F., Lei, C. L., Preston, S. P., Wilkinson, R. D., & Mirams, G. R. Optimising experimental designs for model selection of ion channel drug binding mechanisms

The rapid delayed rectifier current carried by the human Ether-à-go-go-Related Gene (hERG) channel is susceptible to drug-induced reduction which can lead to an increased risk of cardiac arrhythmia. Establishing the mechanism by which a specific drug... Read More about Optimising experimental designs for model selection of ion channel drug binding mechanisms.

MPeat2D - a fully coupled mechanical-ecohydrological model of peatland development in two dimensions (2024)
Journal Article
Mahdiyasa, A. W., Large, D. J., Icardi, M., & Muljadi, B. P. (2024). MPeat2D - a fully coupled mechanical-ecohydrological model of peatland development in two dimensions. Earth Surface Dynamics, 12(4), 929-952. https://doi.org/10.5194/esurf-12-929-2024

Higher-dimensional models of peatland development are required to analyse the influence of spatial heterogeneity and complex feedback mechanisms on peatland behaviour. However, the current models exclude the mechanical process that leads to uncertain... Read More about MPeat2D - a fully coupled mechanical-ecohydrological model of peatland development in two dimensions.

Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs (2024)
Preprint / Working Paper
Shuttleworth, J. G., Lei, C. L., Windley, M. J., Hill, A. P., Preston, S. P., & Mirams, G. R. Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs

Mathematical models are increasingly being relied upon to provide quantitatively accurate predictions of cardiac electrophysiology. Many such models concern the behaviour of particular subcellular components (namely, ion channels) which, together, al... Read More about Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs.

A range of voltage-clamp protocol designs for rapid capture of hERG kinetics (2024)
Preprint / Working Paper
Lei, C. L., Whittaker, D. G., Windley, M. J., Perry, M. D., Hill, A. P., & Mirams, G. R. A range of voltage-clamp protocol designs for rapid capture of hERG kinetics

We provide details of a series of short voltage-clamp protocols designed for gathering a large amount of information on hERG (Kv11.1) ion channel gating. The protocols have a limited number of steps and consist only of steps and ramps, making them ea... Read More about A range of voltage-clamp protocol designs for rapid capture of hERG kinetics.

Geometry of Spin(10) symmetry breaking (2024)
Journal Article
Krasnov, K. (2024). Geometry of Spin(10) symmetry breaking. Journal of Mathematical Physics, 65(8), Article 082302. https://doi.org/10.1063/5.0210073

We provide a new characterisation of the Standard Model gauge group GSM as a subgroup of Spin(10). The new description of GSM relies on the geometry of pure spinors. We show that GSM ⊂ Spin(10) is the group that stabilises a pure spinor Ψ1 and projec... Read More about Geometry of Spin(10) symmetry breaking.

Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping (2024)
Preprint / Working Paper
Kyratzi, P., Matika, O., Brassington, A. H., Connie, C. E., Xu, J., Barrett, D. A., Emes, R. D., Archibald, A. L., Paldi, A., Sinclair, K. D., Wattis, J., & Rauch, C. Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping

Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using averages and varia... Read More about Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping.

The Conversationality Index: A quantitative assessment of conversation in social media interactions (2024)
Journal Article
Cotgrove, L., Thul, R., & Conklin, K. (in press). The Conversationality Index: A quantitative assessment of conversation in social media interactions. Internet Pragmatics,

There has been an explosion in social media use, with Statista estimating that worldwide, Facebook has over 3 billion regular active users, YouTube 2.5 billion, and Instagram and WhatsApp 2 billion. While social media allows one to connect and intera... Read More about The Conversationality Index: A quantitative assessment of conversation in social media interactions.

Deep NURBS—admissible physics-informed neural networks (2024)
Journal Article
Saidaoui, H., Espath, L., & Tempone, R. (2024). Deep NURBS—admissible physics-informed neural networks. Engineering with Computers, https://doi.org/10.1007/s00366-024-02040-9

In this study, we propose a new numerical scheme for physics-informed neural networks (PINNs) that enables precise and inexpensive solutions for partial differential equations (PDEs) in case of arbitrary geometries while strongly enforcing Dirichlet... Read More about Deep NURBS—admissible physics-informed neural networks.