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In vitro determination of essential genes required by Streptococcus uberis to grow in a complex biological media relating to intramammary infection (2025)
Journal Article
Blanchard, A. M., & Leigh, J. A. (2025). In vitro determination of essential genes required by Streptococcus uberis to grow in a complex biological media relating to intramammary infection. Microbial Genomics, 11(6), Article 001425. https://doi.org/10.1099/mgen.0.001425

Streptococcus uberis is a leading cause of bovine mastitis, a disease of significant economic impact to the dairy industry. Understanding the genetic factors essential for bacterial survival in milk and during intramammary infection is crucial for de... Read More about In vitro determination of essential genes required by Streptococcus uberis to grow in a complex biological media relating to intramammary infection.

Genome-Wide Association Study Identifies Novel Genetic Variants Associated with Widespread Pain in the UK Biobank (N=172,230) (2025)
Journal Article
Pan, Q., Cai, T., Tao, Y., Compte, R., Naeini, M. K., Haque, M., Dottorini, T., Williams, F. M., & Meng, W. (2025). Genome-Wide Association Study Identifies Novel Genetic Variants Associated with Widespread Pain in the UK Biobank (N=172,230). Molecular Pain, 21, https://doi.org/10.1177/17448069251346603

Objectives:Widespread pain is a hallmark characteristic of fibromyalgia, commonly affecting older individuals. This study aimed to identify novel genetic variants associated with widespread pain by utilizing the extensive UK Biobank dataset.

Metho... Read More about Genome-Wide Association Study Identifies Novel Genetic Variants Associated with Widespread Pain in the UK Biobank (N=172,230).

Comparing expert stakeholders’ assessments of the relative impact of management practices on dairy calf welfare using best-worst scaling (2025)
Journal Article
Smith, A.-L., Doidge, C., & Kaler, J. (2025). Comparing expert stakeholders’ assessments of the relative impact of management practices on dairy calf welfare using best-worst scaling. Preventive Veterinary Medicine, 242, Article 106587. https://doi.org/10.1016/j.prevetmed.2025.106587

The UK dairy industry is under increasing public scrutiny, with growing intensification sparking concerns for farm animal health and welfare. Despite established best practices, achieving optimal calf health and welfare remains an industry-wide chall... Read More about Comparing expert stakeholders’ assessments of the relative impact of management practices on dairy calf welfare using best-worst scaling.

Comprehensive genome catalog analysis of the resistome, virulome and mobilome in the wild rodent gut microbiota (2025)
Journal Article
Shang, K.-M., Ma, H., Elsheikha, H. M., Wei, Y.-J., Zhao, J.-X., Qin, Y., Li, J.-M., Zhao, Z.-Y., & Zhang, X.-X. (2025). Comprehensive genome catalog analysis of the resistome, virulome and mobilome in the wild rodent gut microbiota. npj Biofilms and Microbiomes, 11, Article 101. https://doi.org/10.1038/s41522-025-00746-2

Wild rodent’s gut microbiota serves as a crucial reservoir of antibiotic resistance genes (ARGs), where antimicrobial-resistant bacteria interact with mobile genetic elements (MGEs) to facilitate horizontal gene transfer. This study analyzed 12,255 g... Read More about Comprehensive genome catalog analysis of the resistome, virulome and mobilome in the wild rodent gut microbiota.

Mesenchymal Stem Cells: A Double‐Edged Approach for Managing Cutaneous Leishmaniasis Lesions (2025)
Journal Article
Foroutan, M., Majidiani, H., Elsheikha, H. M., Saeedi-Boroujeni, A., Bahadory, S., Saberi, R., Shirzadshahrivar, A., Mahmoud Hashemi, S., & Soudi, S. (2025). Mesenchymal Stem Cells: A Double‐Edged Approach for Managing Cutaneous Leishmaniasis Lesions. International Wound Journal, 22(6), Article e70709. https://doi.org/10.1111/iwj.70709

Leishmania spp. are intracellular protozoan parasites responsible for leishmaniasis, a globally prevalent vector-borne disease transmitted by phlebotomine sandflies. Within vertebrate hosts, the parasites preferentially infect macrophages and dendrit... Read More about Mesenchymal Stem Cells: A Double‐Edged Approach for Managing Cutaneous Leishmaniasis Lesions.

Assessment of Vitamin D Status in Great Apes in Human Care (2025)
Journal Article
Liptovszky, M., Reeves, C., Jarvis, R., Baiker, K., Dobbs, P., White, K., & Moittié, S. (2025). Assessment of Vitamin D Status in Great Apes in Human Care. Zoo Biology, https://doi.org/10.1002/zoo.21908

Reliably assessing vitamin D status in nonhuman great apes presents unique challenges, including the optimal collection, handling and storage of appropriate samples, assay selection, and interpretation of results. In recent decades, significant scien... Read More about Assessment of Vitamin D Status in Great Apes in Human Care.

The Role of Epithelial-Derived Extracellular Vesicles in Allergic Sensitisation: A Systematic Review (2025)
Journal Article
Browne, W., Hopkins, G., Cochrane, S., James, V., Onion, D., & C. Fairclough, L. (2025). The Role of Epithelial-Derived Extracellular Vesicles in Allergic Sensitisation: A Systematic Review. International Journal of Molecular Sciences, 26(12), Article 5791. https://doi.org/10.3390/ijms26125791

The aim of this systematic review was to evaluate the current evidence for the involvement of epithelial-derived extracellular vesicles (EVs) in Immunoglobulin E (IgE)-mediated allergic sensitisation. Original clinical and research studies specifical... Read More about The Role of Epithelial-Derived Extracellular Vesicles in Allergic Sensitisation: A Systematic Review.

Descriptive analysis of national bovine viral diarrhoea test data in England (2016–2023) (2025)
Journal Article
Prosser, N. S., Hill, E. M., Gow, L., Cavallaro, M., Tildesley, M. J., Keeling, M. J., Kaler, J., Ferguson, E., & Green, M. J. (2025). Descriptive analysis of national bovine viral diarrhoea test data in England (2016–2023). Veterinary Record, https://doi.org/10.1002/vetr.5325

Background: Bovine viral diarrhoea (BVD)is an endemic disease in the UK. In England, a voluntary control and eradication scheme, BVDFree England, has been running since 2016. Methods: We analysed test results from 7005 herds that were submitted to BV... Read More about Descriptive analysis of national bovine viral diarrhoea test data in England (2016–2023).

Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network (2025)
Journal Article
Becker, Y., Eichner, C., Paquette, M., Bock, C., Girard-Buttoz, C., Jäger, C., Gräßle, T., Deschner, T., Zuberbühler, K., Wood, K., Wibbelt, G., Weiskopf, N., Walker, S., Unwin, S., Ulrich, R., Tanga, T., Szentiks, C. A., Southern, L., Stidworthy, M. F., Steiner, J., …Anwander, A. (2025). Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network. Nature Communications, 16(1), Article 4485. https://doi.org/10.1038/s41467-025-59254-8

The arcuate fascicle (AF) is the main fibre tract in the brain for human language. It connects frontal and temporal language areas in the superior and middle temporal gyrus (MTG). The AF’s connection to the MTG was considered unique to humans and has... Read More about Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network.

Efficiency of isoflurane capture from anaesthetised veterinary patients: a single-centre study of a volatile capture device (2025)
Journal Article
White, K. L., West, E., Yarnall, H., & Sparks, T. (2025). Efficiency of isoflurane capture from anaesthetised veterinary patients: a single-centre study of a volatile capture device. British Journal of Anaesthesia, 135(1), 276-278. https://doi.org/10.1016/j.bja.2025.03.034

Medical healthcare has been forward in acknowledging its greenhouse gas emissions, which contribute to the existential risk from climate change.1,2 There is similar concern in veterinary healthcare.3,4 An estimated 21% of the carbon emissions for a c... Read More about Efficiency of isoflurane capture from anaesthetised veterinary patients: a single-centre study of a volatile capture device.

AP2X-8 Is Important for Tachyzoite Growth and Bradyzoite Differentiation of Toxoplasma gondii (2025)
Journal Article
Sun, L.-X., Wang, M., Elsheikha, H. M., Xie, S.-C., Fu, B.-Q., Zhu, X.-Q., & Liu, G.-H. (2025). AP2X-8 Is Important for Tachyzoite Growth and Bradyzoite Differentiation of Toxoplasma gondii. Animals, 15(9), Article 1349. https://doi.org/10.3390/ani15091349

Toxoplasma gondii is a protozoan parasite capable of establishing chronic infections, with potential reactivation in immunocompromised individuals. However, the molecular mechanisms governing tachyzoite-to-bradyzoite differentiation remain incomplete... Read More about AP2X-8 Is Important for Tachyzoite Growth and Bradyzoite Differentiation of Toxoplasma gondii.

Anti-Müllerian hormone, antral follicle count, and progesterone evaluation in Italian Mediterranean buffalo heifers (2025)
Journal Article
Monti, S., la Spisa, M., Capuzzello, G., di Giorgio, S., Arfuso, F., & Marino, G. (2025). Anti-Müllerian hormone, antral follicle count, and progesterone evaluation in Italian Mediterranean buffalo heifers. Large Animal Review, 31(2), 67-70

Anti-Müllerian hormone (AMH) has been used as a molecular marker of the ovarian follicular pool and follicular responsiveness to superovulation treatments in cattle and other species. Early studies in buffalo cows indicated that circulating AMH level... Read More about Anti-Müllerian hormone, antral follicle count, and progesterone evaluation in Italian Mediterranean buffalo heifers.

Widespread pesticide pollution in two English river catchments of contrasting land-use: from sediments to fish (2025)
Journal Article
Ramage, C. I., Alfama Lopes dos Santos, R., Yon, L., Johnson, M. F., & Vane, C. H. (2025). Widespread pesticide pollution in two English river catchments of contrasting land-use: from sediments to fish. Environmental Pollution, 375, Article 126371. https://doi.org/10.1016/j.envpol.2025.126371

Water, sediments, fish and invertebrates were collected along two English rivers (R. Tone, Sommerset and R. Wensum, Norfolk) and analysed for 52 pesticides to assess source to sea spatial distribution and track bioaccumulation within wildlife. Chemic... Read More about Widespread pesticide pollution in two English river catchments of contrasting land-use: from sediments to fish.

In Silico–Based Investigation of the Immunogenicity and Biochemical Attributes of Toxoplasma gondii Apical Membrane Antigen 1 (TgAMA1) (2025)
Journal Article
Foroutan, M., Ghaffari, A. D., Ghaffarifar, F., Karimipour-Saryazdi, A., Birgani, A. A., Majidiani, H., Cortes, H., & Elsheikha, H. M. (2025). In Silico–Based Investigation of the Immunogenicity and Biochemical Attributes of Toxoplasma gondii Apical Membrane Antigen 1 (TgAMA1). Journal of Parasitology Research, https://doi.org/10.1155/japr/3514414

Background: Apical membrane antigen 1 (AMA1) is a highly conserved microneme protein in apicomplexan parasites. In this study, immunoinformatics tools and in silico protein structure prediction were used to characterize the structure, physicochemical... Read More about In Silico–Based Investigation of the Immunogenicity and Biochemical Attributes of Toxoplasma gondii Apical Membrane Antigen 1 (TgAMA1).

Environmental interference and declining male fertility (2025)
Journal Article
Lea, R. G. (2025). Environmental interference and declining male fertility. Reproduction, Fertility and Development, 37(7), Article RD25047. https://doi.org/10.1071/rd25047

Declining human male ‘fertility’ has been equated with a temporal decline in sperm counts, with reports collectively spanning the period between 1934 and 2018. Although sperm quality is impacted by adult male lifestyle choices, e.g. diet, stress and... Read More about Environmental interference and declining male fertility.

Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens (2025)
Journal Article
Hu, Z., Ai, H., Wang, Z., Huang, S., Sun, H., Xuan, X., Chen, M., Wang, J., Yan, W., Sun, J., Pu, J., Brooke, C. B., Chang, K.-C., Sun, Y., & Liu, J. (2025). Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens. npj Vaccines, 10(1), Article 67. https://doi.org/10.1038/s41541-025-01115-y

H9N2 avian influenza virus (AIV) is endemic in poultry worldwide and increasingly zoonotic. Despite the long-term widespread use of inactivated vaccines, H9N2 AIVs remain dominant in chicken flocks. We demonstrated that inactivated vaccines did not p... Read More about Impact of inactivated vaccine on transmission and evolution of H9N2 avian influenza virus in chickens.

Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes—An In Vitro Approach (2025)
Journal Article
Castanheira, C. I. G. D., Anderson, J. R., Clarke, E. J., Hackl, M., James, V., Clegg, P. D., & Peffers, M. J. (2025). Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes—An In Vitro Approach. International Journal of Molecular Sciences, 26(7), Article 3353. https://doi.org/10.3390/ijms26073353

This study describes a novel technique to analyze the extracellular vesicle (EV)-derived microRNA (miRNA) crosstalk between equine chondrocytes and synoviocytes. Donor cells (chon- drocytes, n=8; synoviocytes, n=9) were labelled with 5-ethynyl uridin... Read More about Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes—An In Vitro Approach.

Future crop breeding needs to consider future soils (2025)
Journal Article
Raza, S., Pandey, B. K., Hawkesford, M. J., Griffiths, S., Bennett, M. J., & Mooney, S. J. (2025). Future crop breeding needs to consider future soils. Nature Plants, 11, 939-941. https://doi.org/10.1038/s41477-025-01977-z

Modern crop breeding and seed certification agencies ignore the known spatial heterogeneity of soils and develop cultivars to thrive in a ‘one-size-fits-all’ soil environment. Neglecting the evolving dynamics of soils substantially undermines the cap... Read More about Future crop breeding needs to consider future soils.