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All Outputs (10)

Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England (2014)
Journal Article
Kuo, C.-F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2014). Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England. Journal of the American Medical Association, 312(24), https://doi.org/10.1001/jama.2014.14484

Gout is caused by urate crystal deposition secondary to persistent hyperuricemia. Current guidelines recommend urate-lowering treatment to prevent crystal deposition and encourage crystal dissolution for patients with more severe gout or concomitant... Read More about Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England.

Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms (2014)
Journal Article
Hall, M. C., Doherty, S., Courtney, P., Latief, K., Zhang, W., & Doherty, M. (2014). Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms. Osteoarthritis and Cartilage, 22(10), https://doi.org/10.1016/j.joca.2014.05.025

OBJECTIVE: To [1] compare the frequency and severity of ultrasound (US) features in people with normal knees (controls), knee pain (KP), asymptomatic radiographic OA (ROA), and symptomatic OA (SROA), [2] examine relationships between US features, pai... Read More about Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms.

The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012 (2014)
Journal Article
Rees, F., Doherty, M., Grainge, M. J., Davenport, G., Lanyon, P., & Zhang, W. (in press). The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012. Annals of the Rheumatic Diseases, 75(1), https://doi.org/10.1136/annrheumdis-2014-206334

Objectives: To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999–2012.

Methods: A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculate... Read More about The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012.

Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study. (2014)
Journal Article
McWilliams, D. F., Muthuri, S., Muir, K. R., Maciewicz, R. A., Zhang, W., & Doherty, M. (2014). Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study. BMC Musculoskeletal Disorders, 15(1), https://doi.org/10.1186/1471-2474-15-308

Background: Biomechanical factors may play a role in osteoarthritis (OA) development and progression. Previous biomechanical studies have indicated that types of footwear may modulate forces across the knee joint, and high heeled womens' shoes in par... Read More about Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study..

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study (2014)
Journal Article
Doherty, S., Zhang, W., Maciewicz, R., Doherty, M., Muir, K., Abhishek, A., & Valdes, A. M. (2014). The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study. Arthritis Research and Therapy, 16(1), Article R25. https://doi.org/10.1186/ar4453

Introduction
Chondrocalcinosis (CC) most commonly results from calcium pyrophosphate crystal deposition (CPPD). The objective of this study is to examine the association between candidate single-nucleotide polymorphisms (SNPs) and radiographic CC.... Read More about The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study.

Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial (2014)
Journal Article
Mu, R., Bao, C. D., Chen, Z. W., Zheng, Y., Wang, G. C., Zhao, D. B., …Li, Z. G. (2016). Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial. Clinical Rheumatology, 35(1), 165-173. https://doi.org/10.1007/s10067-014-2701-4

© 2014, Clinical Rheumatology. This study is aimed at comparing the efficacy and safety of loxoprofen sodium hydrogel patch (LX-P) with loxoprofen sodium tablet (LX-T) in patients with knee osteoarthritis (OA). One hundred sixty-nine patients were en... Read More about Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial.

Ultrasound detected synovial change and pain response following intra-articular injection of corticosteroid and a placebo in symptomatic osteoarthritic knees: a pilot study (2014)
Journal Article
Hall, M. C., Doherty, S., Courtney, P., Latief, K., Zhang, W., & Doherty, M. (in press). Ultrasound detected synovial change and pain response following intra-articular injection of corticosteroid and a placebo in symptomatic osteoarthritic knees: a pilot study. Annals of the Rheumatic Diseases, 73(8), https://doi.org/10.1136/annrheumdis-2014-205206

Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis (2014)
Journal Article
Juhl, C., Christensen, R., Roos, E. M., Zhang, W., & Lund, H. (2014). Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis. Arthritis and Rheumatology, 66(3), 622-636. https://doi.org/10.1002/art.38290

Objective: To identify the optimal exercise program, characterized by type and intensity of exercise, length of program, duration of individual supervised sessions, and number of sessions per week, for reducing pain and patient-reported disability in... Read More about Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis.

Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study (2014)
Journal Article
Kuo, C. F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2015). Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study. Annals of the Rheumatic Diseases, 74(4), 661-667. https://doi.org/10.1136/annrheumdis-2013-204463

Objectives: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. Methods: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study.