All Outputs (3)

Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review) (2017)
Journal Article
Harrison, R. P., & Chauhan, V. M. (2018). Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review). Biointerphases, 13(1), Article 01A301-1-01A301-8. https://doi.org/10.1116/1.5013335

Cell and gene therapies (CGTs) are examples of future therapeutics that can be used to cure or alleviate the symptoms of disease, by repairing damaged tissue or reprogramming defective genetic information. However, despite the recent advancements in... Read More about Enhancing cell and gene therapy manufacture through the application of advanced fluorescent optical sensors (Review).

The physicochemical fingerprint of Necator americanus (2017)
Journal Article
Chauhan, V. M., Scurr, D. J., Christie, T., Telford, G., Aylott, J. W., & Pritchard, D. (in press). The physicochemical fingerprint of Necator americanus. PLoS Neglected Tropical Diseases, 11(12), Article e0005971. https://doi.org/10.1371/journal.pntd.0005971

Necator americanus, a haematophagous hookworm parasite, infects ~10% of the world’s population and is considered to be a significant public health risk. Its lifecycle has distinct stages, permitting its successful transit from the skin via the lungs... Read More about The physicochemical fingerprint of Necator americanus.

Real-time measurement of the intracellular pH of yeast cells during glucose metabolism using ratiometric fluorescent nanosensors (2017)
Journal Article
Elsutohy, M. M., Chauhan, V. M., Markus, R., Kyyaly, M. A., Tendler, S. J., & Aylott, J. W. (2017). Real-time measurement of the intracellular pH of yeast cells during glucose metabolism using ratiometric fluorescent nanosensors. Nanoscale, 9(18), 5904-5911. https://doi.org/10.1039/c7nr00906b

Intracellular pH is a key parameter that influences many biochemical and metabolic pathways that can also be used as an indirect marker to monitor metabolic and intracellular processes. Herein, we utilise ratiometric fluorescent pH-sensitive nanosens... Read More about Real-time measurement of the intracellular pH of yeast cells during glucose metabolism using ratiometric fluorescent nanosensors.