All Outputs (15)

Contribution of inflammation markers and quantitative sensory testing (QST) indices of central sensitisation to rheumatoid arthritis pain (2024)
Journal Article
Georgopoulos, V., Smith, S., McWilliams, D. F., Ferguson, E., Wakefield, R., Platts, D., Ledbury, S., Wilson, D., & Walsh, D. A. (2024). Contribution of inflammation markers and quantitative sensory testing (QST) indices of central sensitisation to rheumatoid arthritis pain. Arthritis Research and Therapy, 26(1), Article 175. https://doi.org/10.1186/s13075-024-03407-5

Background: Pain, the primary complaint in rheumatoid arthritis (RA), is multifaceted, and may be driven by inflammatory disease activity and central sensitisation. We aimed to ascertain what proportion of RA pain severity is explained by markers of... Read More about Contribution of inflammation markers and quantitative sensory testing (QST) indices of central sensitisation to rheumatoid arthritis pain.

Mechanisms of manipulation: a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation (2024)
Journal Article
Young, K. J., Leboeuf-Yde, C., Gorrell, L., Bergström, C., Evans, D. W., Axén, I., Chance-Larsen, K., Gagey, O., Georgopoulos, V., Goncalves, G., Harris, C., Harsted, S., Kerry, R., Lee, E., McCarthy, C., Nim, C., Nyirö, L., Schweinhardt, P., & Vogel, S. (2024). Mechanisms of manipulation: a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation. Chiropractic & Manual Therapies, 32(1), Article 28. https://doi.org/10.1186/s12998-024-00549-w

Background
Spinal manipulation (SM) has been claimed to change anatomy, either in structure or position, and that these changes may be the cause of clinical improvements. The aim of this systematic review was to evaluate and synthesise the peer-revi... Read More about Mechanisms of manipulation: a systematic review of the literature on immediate anatomical structural or positional changes in response to manually delivered high-velocity, low-amplitude spinal manipulation.

Pharmacological Treatment of Musculoskeletal Pain (2024)
Other
Georgopoulos, V. (2024). Pharmacological Treatment of Musculoskeletal Pain. [Internet Resource]

Musculoskeletal pain management should accommodate patient
choice, sensory and emotional aspects of pain, its diverse mechanisms
in both peripheral and central nervous systems, and its context,
including diagnosis, disability and co-morbidities, e... Read More about Pharmacological Treatment of Musculoskeletal Pain.

Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire (2024)
Journal Article
McWilliams, D., Georgopoulos, V., Patel, J., Millar, B., Smith, S., & Walsh, D. (2024). Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire. Rheumatology, https://doi.org/10.1093/rheumatology/keae342

Background

Neuropathic-like pain, fatigue, cognitive difficulty, catastrophizing, anxiety, sleep disturbance, depression and widespread pain associate with a single factor in people with knee pain. We report the Central Aspects of Pain questionnai... Read More about Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire.

A modern way to teach and practice manual therapy (2024)
Journal Article
Kerry, R., Young, K. J., Evans, D. W., Lee, E., Georgopoulos, V., Meakins, A., …Hutting, N. (2024). A modern way to teach and practice manual therapy. Chiropractic & Manual Therapies, 32(1), Article 17. https://doi.org/10.1186/s12998-024-00537-0

Background: Musculoskeletal conditions are the leading contributor to global disability and health burden. Manual therapy (MT) interventions are commonly recommended in clinical guidelines and used in the management of musculoskeletal conditions. Tra... Read More about A modern way to teach and practice manual therapy.

The interrater and test–retest reliability of 3 modalities of quantitative sensory testing in healthy adults and people with chronic low back pain or rheumatoid arthritis (2023)
Journal Article
Brady, S. M., Georgopoulos, V., Veldhuijzen van Zanten, J. J., Duda, J. L., Metsios, G. S., Kitas, G. D., …McWilliams, D. F. (2023). The interrater and test–retest reliability of 3 modalities of quantitative sensory testing in healthy adults and people with chronic low back pain or rheumatoid arthritis. PAIN Reports, 8(6), Article e1102. https://doi.org/10.1097/pr9.0000000000001102

Introduction:
Quantitative Sensory Testing (QST) modalities used to assess central pain mechanisms require different protocols in people with different musculoskeletal conditions.

Objectives:
We aimed to explore the possible effects of musculo... Read More about The interrater and test–retest reliability of 3 modalities of quantitative sensory testing in healthy adults and people with chronic low back pain or rheumatoid arthritis.

Influence of central aspects of pain on self-management in people with chronic low back pain (2023)
Journal Article
Georgopoulos, V., McWilliams, D. F., Hendrick, P., & Walsh, D. A. (2023). Influence of central aspects of pain on self-management in people with chronic low back pain. Patient Education and Counseling, 121, Article 108109. https://doi.org/10.1016/j.pec.2023.108109

Objective: This observational study investigated whether central aspects of pain are associated with self-management domains in individuals with chronic low back pain (CLBP) undertaking a pain management program. Methods: Individuals with CLBP provid... Read More about Influence of central aspects of pain on self-management in people with chronic low back pain.

Reply on: International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia (2023)
Journal Article
Kundakci, B., Hall, M., Atzeni, F., Branco, J., Buskila, D., Clauw, D., …Abhishek, A. (2023). Reply on: International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia. Seminars in Arthritis and Rheumatism, 59, Article 152162. https://doi.org/10.1016/j.semarthrit.2023.152162

Reproducible microbiome composition signatures of anxiety and depressive symptoms (2023)
Journal Article
Kouraki, A., Kelly, A., Vijay, A., Gohir, S., Astbury, S., Georgopoulos, V., …Valdes, A. M. (2023). Reproducible microbiome composition signatures of anxiety and depressive symptoms. Computational and Structural Biotechnology Journal, 21, 5326-5336. https://doi.org/10.1016/j.csbj.2023.10.035

The gut microbiome is a significant contributor to mental health, with growing evidence linking its composition to anxiety and depressive disorders. Gut microbiome composition is associated with signs of anxiety and depression both in clinically diag... Read More about Reproducible microbiome composition signatures of anxiety and depressive symptoms.

CAN CONTINUOUS KNEE PAIN OUTCOME MEASURES BE HARMONISED? (2022)
Presentation / Conference Contribution
Georgopoulos, V., Perry, T., Smith, S., McWilliams, D., Gohir, S., Valdes, A., …Walsh, D. (2022). CAN CONTINUOUS KNEE PAIN OUTCOME MEASURES BE HARMONISED?. Osteoarthritis and Cartilage, 30(Supp 1), S15-S17. https://doi.org/10.1016/J.JOCA.2022.02.011

Indices of central sensitisation can predict effective self-management in individuals with chronic low back pain (2020)
Presentation / Conference Contribution
Georgopoulos, V. (2020, September). Indices of central sensitisation can predict effective self-management in individuals with chronic low back pain. Poster presented at IASP Virtual Series on Pain & Expo, online

Background and aims: Chronic low back pain (CLBP) is one of the most prevalent reasons people seek healthcare assistance worldwide. Guidelines for managing CLBP prioritise the development of self-management strategies, for example through cognitive b... Read More about Indices of central sensitisation can predict effective self-management in individuals with chronic low back pain.

Do maladaptive beliefs delay whiplash associated disorders (WAD): A systematic review (2018)
Journal Article
Gabriela Macias, E., Georgopoulos, V., & Taylor, A. (2018). Do maladaptive beliefs delay whiplash associated disorders (WAD): A systematic review. Edorium Journal of Disability and Rehabilitation, 4(1), 1-14. https://doi.org/10.5348/100040d05em2018ra

The purpose of the study is to try to establish if maladaptive beliefs effect recovery times and poor outcomes in whiplash associated disorders (WAD). In May 2017 the following databases were searched from their inception until June 2017: SPORT Discu... Read More about Do maladaptive beliefs delay whiplash associated disorders (WAD): A systematic review.

Clinical prediction rules in the prognosis of whiplash associated disorders: A systematic review (2017)
Presentation / Conference Contribution
Georgopoulos, V., & Taylor, A. (2017). Clinical prediction rules in the prognosis of whiplash associated disorders: A systematic review. Musculoskeletal Science and Practice, 28, e13-e14. https://doi.org/10.1016/j.math.2016.10.036

Clinical prediction rules in the prognosis of Whiplash Associated Disorder (WAD): A systematic review (2016)
Journal Article
Georgopoulos, V., & Taylor, A. (2016). Clinical prediction rules in the prognosis of Whiplash Associated Disorder (WAD): A systematic review. Pain and Rehabilitation, 2016(41), 5-16

Objectives: To identify, evaluate and ascertain the clinical readiness of prognostic Clinical Prediction Rules (CPRs) in the prognosis of Whiplash Associated Disorder (WAD).

Study design: Systematic review

Background: The scientific basis for m... Read More about Clinical prediction rules in the prognosis of Whiplash Associated Disorder (WAD): A systematic review.

P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis
Presentation / Conference Contribution
Abd Elkhabir, A. A., McWilliams, D. F., Smith, S., Chaplin, W., Salimian, M., Georgopoulos, V., Kouraki, A., & Walsh, D. A. (2023, April). P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis. Presented at British Society for Rheumatology Annual Conference 2023, Manchester

Background/Aims

Exercise has shown a promising effect in reducing central sensitisation (CS), but it is unknown which exercise type is the most effective. This review aimed to rank and compare the effectiveness of different exercise interventions... Read More about P073 Comparative effectiveness of different exercise interventions on central sensitisation indices in humans: A systematic review and network meta-analysis.