All Outputs (43)

High glucose mediates prooxidant and antioxidant enzyme activities in coronary endothelial cells (2004)
Journal Article
Bayraktutan, U., Weidig, P., McMaster, D., & Ulker, S. (2004). High glucose mediates prooxidant and antioxidant enzyme activities in coronary endothelial cells

Objective: Excess levels of free radicals such as nitric oxide (NO) and superoxide anion (O2-)are associated with the pathogenesis of endothelial cell dysfunction in diabetes mellitus. This study was designed to investigate the underlying causes of o... Read More about High glucose mediates prooxidant and antioxidant enzyme activities in coronary endothelial cells.

Vitamins Reverse Endothelial Dysfunction Through Regulation of eNOS and NAD(P)H Oxidase Activities (2003)
Journal Article
Ulker, S., McKeown, P., & Bayraktutan, U. (2003). Vitamins Reverse Endothelial Dysfunction Through Regulation of eNOS and NAD(P)H Oxidase Activities. Hypertension, 41,

Antioxidant vitamins C and E have protective properties in genetic hypertension associated with enhanced
oxidative stress. This study investigated whether vitamins C and/or E modulate vascular function by regulating
enzymatic activities of endothel... Read More about Vitamins Reverse Endothelial Dysfunction Through Regulation of eNOS and NAD(P)H Oxidase Activities.

Molecular Characterization and Localization of the NAD(P)H Oxidase Components gp91-phox and p22-phox in Endothelial Cells (2000)
Journal Article
Bayraktutan, U., Blayney, L., & Shah, A. (2000). Molecular Characterization and Localization of the NAD(P)H Oxidase Components gp91-phox and p22-phox in Endothelial Cells

The production of reactive oxygen species (ROS) within endothelial cells may have several effects, including
alterations in the activity of paracrine factors, gene expression, apoptosis, and cellular injury. Recent studies indicate that
a phagocyte... Read More about Molecular Characterization and Localization of the NAD(P)H Oxidase Components gp91-phox and p22-phox in Endothelial Cells.