All Outputs (8)

Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study (2020)
Journal Article
Lawrence, H., Pick, H., Baskaran, V., Daniel, P., Rodrigo, C., Ashton, D., …Lim, W. S. (2020). Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study. PLoS Medicine, 17(10), Article e1003326. https://doi.org/10.1371/journal.pmed.1003326

Background: Vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPV23) is available in the UK to adults aged 65 years or over and those in defined clinical risk groups. We evaluated the vaccine effectiveness (VE) of PPV23 against vac... Read More about Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study.

Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies (2020)
Journal Article
Chalitsios, C. V., Shaw, D. E., & McKeever, T. M. (2020). Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies. Thorax, 76(1), 21-28. https://doi.org/10.1136/thoraxjnl-2020-215664

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. Background Inhaled (ICS) and oral (OCS) corticosteroids are used widely in asthma; however, the risk of osteoporosis and fragility fracture (... Read More about Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies.

Cerebrovascular accident and acute coronary syndrome and perioperative outcomes (CAPO) study protocol: a 10-year database linkage between Hospital Episode Statistics Admitted Patient Care, Myocardial Infarction National Audit Project and Office for National Statistics registries for time-dependent risk analysis of perioperative outcomes in English NHS hospitals (2020)
Journal Article
Luney, M., Lindsay, W., McKeever, T. M., & Moppett, I. K. (2020). Cerebrovascular accident and acute coronary syndrome and perioperative outcomes (CAPO) study protocol: a 10-year database linkage between Hospital Episode Statistics Admitted Patient Care, Myocardial Infarction National Audit Project and Office for National Statistics registries for time-dependent risk analysis of perioperative outcomes in English NHS hospitals. BMJ Open, 10(10), Article e037904. https://doi.org/10.1136/bmjopen-2020-037904

Introduction: An increasing number of people who have a history of acute coronary syndrome or cerebrovascular accident (termed cardiovascular events) are being considered for surgery. Up-to-date evidence of the impact of these prior events is needed... Read More about Cerebrovascular accident and acute coronary syndrome and perioperative outcomes (CAPO) study protocol: a 10-year database linkage between Hospital Episode Statistics Admitted Patient Care, Myocardial Infarction National Audit Project and Office for National Statistics registries for time-dependent risk analysis of perioperative outcomes in English NHS hospitals.

Variation in clinical outcomes and process of care measures in Community Acquired Pneumonia: a systematic review (2020)
Journal Article
Lawrence, H., Lim, W., & McKeever, T. (2020). Variation in clinical outcomes and process of care measures in Community Acquired Pneumonia: a systematic review. Pneumonia, 12, Article 10. https://doi.org/10.1186/s41479-020-00073-4

Background: Variation in outcomes of patients with community acquired pneumonia (CAP) has been reported in some, but not all, studies. Although some variation is expected, unwarranted variation in healthcare impacts patient outcomes and equity of car... Read More about Variation in clinical outcomes and process of care measures in Community Acquired Pneumonia: a systematic review.

Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study (2020)
Journal Article
Tan, S., Szatkowski, L., Moreton, W., Fiaschi, L., McKeever, T., Gibson, J., & Sharkey, D. (2020). Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study. European Respiratory Journal, 56(1), Article 2000202. https://doi.org/10.1183/13993003.00202-2020

Background Globally, bronchopulmonary dysplasia (BPD) continues to increase in preterm infants. Recent studies exploring subsequent early childhood respiratory morbidity have been small or focused on hospital admissions.

Primary aim Examine early... Read More about Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study.

Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching (2020)
Journal Article
Morgan, L., McKeever, T. M., Nightingale, J., Deakin, D. E., & Moppett, I. K. (2020). Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching. Anaesthesia, 75(9), 1173-1179. https://doi.org/10.1111/anae.15042

Around 76,000 people fracture their hip annually in the UK at a considerable personal, social and financial cost. Despite longstanding debate, the optimal mode of anaesthesia (general or spinal) remains unclear. Our aim was to assess whether there is... Read More about Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching.

Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia (2020)
Journal Article
Lawrence, H., McKeever, T. M., & Lim, W. S. (2020). Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia. Thorax, 75(7), 594-596. https://doi.org/10.1136/thoraxjnl-2019-214318

Outcomes for adults with community-acquired pneumonia (CAP) admitted to hospital at the weekend were compared with those admitted during weekdays using data from the British Thoracic Society national CAP audits. Of 31 400 cases, 40.7% were weekend ad... Read More about Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia.

A systematic review of survival following anti-cancer treatment for small cell lung cancer (2020)
Journal Article
Baldwin, D. R., Jones, G. S., Elimian, K., Hubbard, R. B., & McKeever, T. M. (2020). A systematic review of survival following anti-cancer treatment for small cell lung cancer. Lung Cancer, 141, 44-55. https://doi.org/10.1016/j.lungcan.2019.12.015

Objectives: We conducted a systematic review and meta-analysis of survival following treatment recommended by the European Society of Medical Oncology for SCLC in order to determine a benchmark for novel therapies to be compared with. Materials and m... Read More about A systematic review of survival following anti-cancer treatment for small cell lung cancer.