2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the Aryl Hydrocarbon Receptor

Bazzi, Rana; Bradshaw, Tracey D.; Rowlands, J. Craig; Stevens, Malcolm F.G.; Bell, David Robert

doi:10.1016/j.taap.2009.02.015

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2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the Aryl Hydrocarbon Receptor (2009)
Journal Article
Bazzi, R., Bradshaw, T. D., Rowlands, J. C., Stevens, M. F., & Bell, D. R. (2009). 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the Aryl Hydrocarbon Receptor. Toxicology and Applied Pharmacology, 237(1), https://doi.org/10.1016/j.taap.2009.02.015

2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203) and related compounds are a series
of anti-cancer candidate pharmaceuticals (Table 1.), that have been shown to activate the
AhR. We show that these compounds are high affinity ligands for t... Read More about 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the Aryl Hydrocarbon Receptor.