All Outputs (2)

Acute Toxoplasma gondii infection in cats induced tissue-specific transcriptional response dominated by immune signatures (2018)
Journal Article
Cong, W., Dottorini, T., Khan, F., Emes, R. D., Zhang, F.-K., Zhou, C.-X., …Zhu, X.-Q. (2018). Acute Toxoplasma gondii infection in cats induced tissue-specific transcriptional response dominated by immune signatures. Frontiers in Immunology, 9, Article 2403. https://doi.org/10.3389/fimmu.2018.02403

RNA-sequencing was used to detect transcriptional changes in six tissues of cats, seven days after T. gondii infection. A total of 737 genes were differentially expressed (DEGs), of which 410 were up-regulated and 327 were down-regulated. The liver e... Read More about Acute Toxoplasma gondii infection in cats induced tissue-specific transcriptional response dominated by immune signatures.

A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells (2018)
Journal Article
Tian, A.-L., Lu, M., Calderón-Mantilla, G., Petsalaki, E., Dottorini, T., Tian, X., Wang, Y., Huang, S.-Y., Hou, J.-L., Li, X., Elsheikha, H. M., & Zhu, X.-Q. (2018). A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells. Parasites and Vectors, 11(1), https://doi.org/10.1186/s13071-018-2745-4

Background

The molecular structure of Fasciola gigantica 14-3-3 protein has been characterized. However, the involvement of this protein in parasite pathogenesis remains elusive and its effect on the functions of innate immune cells is unknown. We... Read More about A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells.