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All Outputs (21)

Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire (2024)
Journal Article
McWilliams, D., Georgopoulos, V., Patel, J., Millar, B., Smith, S., & Walsh, D. (2024). Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire. Rheumatology, https://doi.org/10.1093/rheumatology/keae342

Background Neuropathic-like pain, fatigue, cognitive difficulty, catastrophizing, anxiety, sleep disturbance, depression and widespread pain associate with a single factor in people with knee pain. We report the Central Aspects of Pain questionnai... Read More about Validation of a questionnaire for central nervous system aspects of joint pain: the CAP questionnaire.

Association between quadriceps tendon elasticity and neuromuscular control in individuals with knee osteoarthritis. (2023)
Journal Article
Dickson, D. M., Smith, S. L., & Hendry, G. J. (2024). Association between quadriceps tendon elasticity and neuromuscular control in individuals with knee osteoarthritis. Clinical Biomechanics, 111, Article 106159. https://doi.org/10.1016/j.clinbiomech.2023.106159

Background: Knee osteoarthritis is a complex condition with established risk factors such as female sex, increasing age and body mass index, reduced quadriceps muscle strength and knee injury. Despite known associated risks, the role and behaviour of... Read More about Association between quadriceps tendon elasticity and neuromuscular control in individuals with knee osteoarthritis..

Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort (2023)
Journal Article
McWilliams, D. F., Yue, B., Smith, S. L., Stocks, J., Doherty, M., Valdes, A. M., …Walsh, D. A. (2023). Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort. Journal of Personalized Medicine, 13(10), Article 1450. https://doi.org/10.3390/jpm13101450

Knee pain is associated with lower muscle strength, and both contribute to disability. Peripheral and central neurological mechanisms contribute to OA pain. Understanding the relative contributions of pain mechanisms to muscle strength might help fut... Read More about Associations of Muscle Strength with Central Aspects of Pain: Data from the Knee Pain and Related Health in the Community (KPIC) Cohort.

Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD) (2022)
Journal Article
Georgopoulos, V., Smith, S., McWilliams, D. F., Steultjens, M. P. M., Williams, A., Price, A., …Walsh, D. A. (2023). Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD). Osteoarthritis and Cartilage, 31(1), 83-95. https://doi.org/10.1016/j.joca.2022.08.011

Objective: In order to facilitate data pooling between studies, we explored harmonisation of patient-reported outcome measures (PROMs) in people with knee pain due to osteoarthritis or knee trauma, using the Patient Acceptable Symptom State scores (P... Read More about Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD).

Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review (2022)
Journal Article
Jones, R., Paul, L., Steultjens, M., & Smith, S. L. (2022). Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review. Journal of Cachexia, Sarcopenia and Muscle, 13(6), 2791-2806. https://doi.org/10.1002/jcsm.13064

Lower limb muscle dysfunction is a key driver for impaired physical capacity and frailty status, both characteristics of sarcopenia. Sarcopenia is the key pathway between frailty and disability. Identifying biological markers for early diagnosis, tre... Read More about Biomarkers associated with lower limb muscle function in individuals with sarcopenia: a systematic review.

Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon (2022)
Journal Article
Dickson, D. M., Smith, S. L., & Hendry, G. J. (2022). Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon. Rheumatology International, 42(12), 2241-2251. https://doi.org/10.1007/s00296-022-05184-3

An advanced ultrasound imaging technique, sonoelastography (SE) is used to evaluate tissue elasticity. To determine SE potential to detect pathological-related changes, and characteristics related to tendon pathology we aimed to (1) compare quadricep... Read More about Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon.

An observational study of centrally facilitated pain in individuals with chronic low back pain (2022)
Journal Article
Georgopoulos, V., Akin-Akinyosoye, K., Smith, S., McWilliams, D. F., Hendrick, P., & Walsh, D. A. (2022). An observational study of centrally facilitated pain in individuals with chronic low back pain. PAIN Reports, 7(3), Article e1003. https://doi.org/10.1097/PR9.0000000000001003

Central pain facilitation can hinder recovery in people with chronic low back pain (CLBP). The aim of this observational study was to investigate whether indices of centrally facilitated pain are associated with pain outcomes in a hospital-based coho... Read More about An observational study of centrally facilitated pain in individuals with chronic low back pain.

Can patient characteristics explain variance in ultrasound strain elastography measures of the quadratus femoris and patellar tendons? (2021)
Journal Article
Dickson, D. M., Smith, S. L., & Hendry, G. J. (2021). Can patient characteristics explain variance in ultrasound strain elastography measures of the quadratus femoris and patellar tendons?. Knee, 28, 282-293. https://doi.org/10.1016/j.knee.2020.12.011

Objectives To explore the associations between participant characteristics and magnitudes of difference in paired elastography measures of knee tendon from different ultrasound systems, and to compare strain elastography pattern description. Material... Read More about Can patient characteristics explain variance in ultrasound strain elastography measures of the quadratus femoris and patellar tendons?.

Intermachine Variation of Ultrasound Strain Elastographic Measures of the Quadriceps and Patellar Tendons in Healthy Participants: Implications for Clinical Practice (2020)
Journal Article
Dickson, D. M., Fawole, H. O., Hendry, G. J., & Smith, S. L. (2020). Intermachine Variation of Ultrasound Strain Elastographic Measures of the Quadriceps and Patellar Tendons in Healthy Participants: Implications for Clinical Practice. Journal of Ultrasound in Medicine, 39(7), 1343-1353. https://doi.org/10.1002/jum.15228

Objectives To evaluate intermachine variation and compare intraoperator and interoperator agreement and repeatability characteristics of 2 ultrasound (US) systems for measurements of quadriceps and patellar tendons by strain elastography (SE). Me... Read More about Intermachine Variation of Ultrasound Strain Elastographic Measures of the Quadriceps and Patellar Tendons in Healthy Participants: Implications for Clinical Practice.

Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways (2019)
Journal Article
Price, A. J., Ogollah, R., Kang, S., Hay, E., Barker, K. L., Benedetto, E., …Hill, J. C. (2019). Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways. BMJ Open, 9(10), 1-7. https://doi.org/10.1136/bmjopen-2018-025357

Objectives: We have previously developed and validated the Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways, showing encouraging psychometric test results. The objective of this study wa... Read More about Determining responsiveness and meaningful changes for the Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways.

Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature (2016)
Journal Article
Dell’Isola, A., Smith, S. L., Allan, R., Steultjens, M., & Marreiros, S. S. P. (2016). Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature. BMC Musculoskeletal Disorders, 17(1), Article 425. https://doi.org/10.1186/s12891-016-1286-2

Background Knee Osteoarthritis (KOA) is a heterogeneous pathology characterized by a complex and multifactorial nature. It has been hypothesised that these differences are due to the existence of underlying phenotypes representing different mechan... Read More about Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature.

Longer Electromechanical Delay Impairs Hamstrings Explosive Force versus Quadriceps (2014)
Journal Article
Hannah, R., Minshull, C., Smith, S. L., & Folland, J. P. (2014). Longer Electromechanical Delay Impairs Hamstrings Explosive Force versus Quadriceps. Medicine and Science in Sports and Exercise, 46(5), 963-972. https://doi.org/10.1249/mss.0000000000000188

Introduction Explosive neuromuscular performance refers to the ability to rapidly increase force in response to neuromuscular activation. The lower explosive force production of the hamstrings relative to the quadriceps could compromise knee join... Read More about Longer Electromechanical Delay Impairs Hamstrings Explosive Force versus Quadriceps.