All Outputs (7)

Atlas-Based Templates vs. Subject-Specific Tractography: Resolving the Debate (2025)
Journal Article
Schilling, K. G., Zhang, F., Tournier, J.-D., Vergani, F., Sotiropoulos, S. N., Rokem, A., & O’Donnell, L. J. (in press). Atlas-Based Templates vs. Subject-Specific Tractography: Resolving the Debate. Brain Structure and Function,

The first annual International Society of Tractography (IST) debate in Corsica in 2024 explored key challenges and controversies in tractography. This article examines the debate sparked by the provocative statement, "Tractography cannot give us anyt... Read More about Atlas-Based Templates vs. Subject-Specific Tractography: Resolving the Debate.

Cross-species Standardised Cortico-Subcortical Tractography (2025)
Journal Article
Assimopoulos, S., Warrington, S., Folloni, D., Bryant, K., Tang, W., Jbabdi, S., Heilbronner, S., Mars, R. B., & Sotiropoulos, S. N. (in press). Cross-species Standardised Cortico-Subcortical Tractography. eLife,

Despite their importance for brain function, cortico-subcortical white matter tracts are underrepresented in diffusion MRI tractography studies. Their non-invasive mapping is more challenging and less explored compared to other major cortico-cortical... Read More about Cross-species Standardised Cortico-Subcortical Tractography.

Uncertainty mapping and probabilistic tractography using Simulation-based Inference in diffusion MRI: A comparison with classical Bayes (2025)
Journal Article
Manzano-Patron, J., Deistler, M., Schröder, C., Kypraios, T., Gonçalves, P. J., Macke, J. H., & Sotiropoulos, S. N. (2025). Uncertainty mapping and probabilistic tractography using Simulation-based Inference in diffusion MRI: A comparison with classical Bayes. Medical Image Analysis, 103, Article 103580. https://doi.org/10.1016/j.media.2025.103580

Simulation-Based Inference (SBI) has recently emerged as a powerful framework for Bayesian inference: Neural networks are trained on simulations from a forward model, and learn to rapidly estimate posterior distributions. We here present an SBI frame... Read More about Uncertainty mapping and probabilistic tractography using Simulation-based Inference in diffusion MRI: A comparison with classical Bayes.

A multi-site, multi-modal travelling-heads resource for brain MRI harmonisation (2025)
Journal Article
Warrington, S., Torchi, A., Mougin, O., Campbell, J., Ntata, A., Craig, M., Assimopoulos, S., Alfaro-Almagro, F., Miller, K., Jenkinson, M., Morgan, P. S., & Sotiropoulos, S. N. (2025). A multi-site, multi-modal travelling-heads resource for brain MRI harmonisation. Scientific Data, 12, Article 609. https://doi.org/10.1038/s41597-025-04822-2

Despite its great potential for studying the living brain, magnetic resonance imaging (MRI) can be often limited by nuisance non-biological factors, such as hardware/software differences between scanners, which can interfere with biological variabili... Read More about A multi-site, multi-modal travelling-heads resource for brain MRI harmonisation.

Cross-Species Neuroanatomy in Primates Using Tractography (2025)
Journal Article
Sotiropoulos, S. N., Thiebaut De Schotten, M., Haber, S. N., & Forkel, S. J. (in press). Cross-Species Neuroanatomy in Primates Using Tractography. Brain Structure and Function,

Due to their integrative role in brain function, long-range white matter connections exhibit high individual variability, giving rise to personalised brain circuits. This neurovariability is more evident in the connection patterns of brain areas that... Read More about Cross-Species Neuroanatomy in Primates Using Tractography.

Connectivity Profile and Function of Uniquely Human Cortical Areas (2025)
Journal Article
Bryant, K. L., Camilleri, J., Warrington, S., Blazquez Freches, G., Sotiropoulos, S. N., Jbabdi, S., Eickhoff, S., & Mars, R. B. (2025). Connectivity Profile and Function of Uniquely Human Cortical Areas. Journal of Neuroscience, 45(15), Article e2017242025. https://doi.org/10.1523/JNEUROSCI.2017-24.2025

Determining the brain specializations unique to humans requires directly comparable anatomical information from other primates, especially our closest relatives. Human (Homo sapiens; m/f), chimpanzee (Pan troglodytes; f), and rhesus macaque (Macaca m... Read More about Connectivity Profile and Function of Uniquely Human Cortical Areas.

Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI (2025)
Journal Article
Sundaresan, V., Zamboni, G., Dineen, R. A., Auer, D. P., Sotiropoulos, S. N., Sprigg, N., Jenkinson, M., & Griffanti, L. (2025). Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI. European Radiology Experimental, 9(1), Article 5. https://doi.org/10.1186/s41747-024-00544-z

Cerebral microbleeds (CMBs) are small, hypointense hemosiderin deposits in the brain measuring 2–10 mm in diameter. As one of the important biomarkers of small vessel disease, they have been associated with various neurodegenerative and cerebrovascul... Read More about Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI.