All Outputs (6)

Label-free Brillouin endo-microscopy for the quantitative 3D imaging of sub-micrometre biology (2024)
Journal Article
La Cavera, S., Chauhan, V. M., Hardiman, W., Yao, M., Fuentes-Domínguez, R., Setchfield, K., …Clark, M. (2024). Label-free Brillouin endo-microscopy for the quantitative 3D imaging of sub-micrometre biology. Communications Biology, 7(1), Article 451. https://doi.org/10.1038/s42003-024-06126-4

This report presents an optical fibre-based endo-microscopic imaging tool that simultaneously measures the topographic profile and 3D viscoelastic properties of biological specimens through the phenomenon of time-resolved Brillouin scattering. This u... Read More about Label-free Brillouin endo-microscopy for the quantitative 3D imaging of sub-micrometre biology.

Plasmonic-based impedance microspectroscopy of optically heterogeneous samples (2020)
Journal Article
Abayzeed, S. A. (2020). Plasmonic-based impedance microspectroscopy of optically heterogeneous samples. Biomedical Optics Express, 11(11), 6168-6180. https://doi.org/10.1364/boe.395474

A robust impedance microscopy technique is presented. This optical tool enables high resolution imaging of electrical properties with promising biophysical applications. The underlying principle is that surface plasmon resonance (SPR) sensors are abl... Read More about Plasmonic-based impedance microspectroscopy of optically heterogeneous samples.

Surface plasmon resonance imaging of excitable cells (2019)
Journal Article
Howe, C. L., Webb, K. F., Abayzeed, S. A., Anderson, D. J., Denning, C., & Russell, N. A. (2019). Surface plasmon resonance imaging of excitable cells. Journal of Physics D: Applied Physics, 52(10), Article 104001. https://doi.org/10.1088/1361-6463/aaf849

Surface plasmons (SPs) are surface charge density oscillations occuring at a metal/dieletric interface and are highly sensitive to refractive index variations adjacent to the surface. This sensitivity has been exploited successfully for chemical and... Read More about Surface plasmon resonance imaging of excitable cells.

Rapid one-step biotinylation of biological and non-biological surfaces (2018)
Journal Article
Henry, S., Williams, E., Barr, K., Korchagina, E., Tuzikov, A., Ilyushina, N., …Bovin, N. (2018). Rapid one-step biotinylation of biological and non-biological surfaces. Scientific Reports, 8(1), Article 2845. https://doi.org/10.1038/s41598-018-21186-3

We describe a rapid one-step method to biotinylate virtually any biological or non-biological surface. Contacting a solution of biotin-spacer-lipid constructs with a surface will form a coating within seconds on non-biological surfaces or within minu... Read More about Rapid one-step biotinylation of biological and non-biological surfaces.

Analysis of noise in differential and ratiometric biosensing systems (2018)
Journal Article
Abayzeed, S., Smith, R. J., See, C. W., & Somekh, M. G. (2018). Analysis of noise in differential and ratiometric biosensing systems. Sensors and Actuators B: Chemical, 260, 1059-1067. https://doi.org/10.1016/j.snb.2018.01.004

This paper presents formulations to evaluate noise in differential and ratiometric measurements that are often performed in biosensing. These measurements are performed to improve signal to noise ratio of the sensing systems for sensitive detection o... Read More about Analysis of noise in differential and ratiometric biosensing systems.

Sensitive detection of voltage transients using differential intensity surface plasmon resonance system (2017)
Journal Article
Abayzeed, S. A., Smith, R. J., Webb, K. F., Somekh, M. G., & See, C. W. (2017). Sensitive detection of voltage transients using differential intensity surface plasmon resonance system. Optics Express, 25(25), 31552-31567. https://doi.org/10.1364/OE.25.031552

This paper describes theoretical and experimental study of the fundamentals of using surface plasmon resonance (SPR) for label-free detection of voltage. Plasmonic voltage sensing relies on the capacitive properties of metal-electrolyte interface tha... Read More about Sensitive detection of voltage transients using differential intensity surface plasmon resonance system.