All Outputs (36)

Identifying neonatal transport research priorities: a modified Delphi consensus (2024)
Journal Article
Mistry, A., Leslie, A., Ojha, S., & Sharkey, D. (2024). Identifying neonatal transport research priorities: a modified Delphi consensus. Archives of Disease in Childhood. Fetal and Neonatal Edition, https://doi.org/10.1136/archdischild-2024-327213

Objectives: With increasing advances in neonatal transport, a focused research strategy is required to increase the evidence base towards providing optimal care. We aimed to identify the most important neonatal transport research questions as priorit... Read More about Identifying neonatal transport research priorities: a modified Delphi consensus.

Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study (2024)
Journal Article
Abramson, J., Szatkowski, L., Bains, M., Orton, E., Budge, H., Spruce, M., & Ojha, S. (2024). Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study. BMJ Open, 14(5), Article e078633. https://doi.org/10.1136/bmjopen-2023-078633

Introduction: Prevention of necrotising enterocolitis (NEC) is vital for improving neonatal outcomes. Feeding own mother’s milk helps prevent NEC. Rates of own mother’s milk feeding in the East Midlands are lower than the national average and the inc... Read More about Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study.

Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis (2024)
Journal Article
Saunders, M., Ojha, S., & Szatkowski, L. (2024). Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis. Archives of Disease in Childhood. Fetal and Neonatal Edition, https://doi.org/10.1136/archdischild-2024-326983

Objective: To assess the impact of publication of UK National Institute for Health and Care Excellence (NICE) guidelines on the prevention and treatment of early-onset infections (EOIs) in neonates (clinical guideline 149 (CG149), published in 2012,... Read More about Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis.

A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study (2024)
Journal Article
Mitchell, E. J., Aluvaala, J., Bradshaw, L., Daniels, J. P., Emadau, C., Muthumbi, B., …Ojha, S. (2024). A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study. BMC Pediatrics, 24, Article 326. https://doi.org/10.1186/s12887-024-04778-z

Preterm birth (< 37 weeks gestation) complications are the leading cause of neonatal mortality. Early-warning scores (EWS) are charts where vital signs (e.g., temperature, heart rate, respiratory rate) are recorded, triggering action. To evaluate whe... Read More about A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study.

Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study (2023)
Journal Article
Szatkowski, L., Sharkey, D., Budge, H., & Ojha, S. (2023). Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study. eClinicalMedicine, 65, Article 102296. https://doi.org/10.1016/j.eclinm.2023.102296

Background: Preterm infants often require mechanical ventilation (MV), which can be a painful experience. Opioids (such as morphine) are used to provide analgesia, despite conflicting evidence about their impact on the developing brain. We aimed to q... Read More about Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study.

Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review (2023)
Journal Article
Kalvala, J., Chong, L., Chadborn, N., & Ojha, S. (2023). Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review. BMJ Paediatrics Open, 7(1), Article e002066. https://doi.org/10.1136/bmjpo-2023-002066

Background: Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, br... Read More about Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review.

How frequent is routine use of probiotics in UK neonatal units? (2023)
Journal Article
Patel, N., Evans, K., Berrington, J., Szatkowski, L., Costeloe, K., Ojha, S., …NeoTRIPS Collaborative Group. (2023). How frequent is routine use of probiotics in UK neonatal units?. BMJ Paediatrics Open, 7(1), Article e002012. https://doi.org/10.1136/bmjpo-2023-002012

Objective There is a lack of UK guidance regarding routine use of probiotics in preterm infants to prevent necrotising enterocolitis, late-onset sepsis and death. As practices can vary, we aimed to determine the current usage of probiotics within neo... Read More about How frequent is routine use of probiotics in UK neonatal units?.

Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom (2023)
Journal Article
Walker, S., Ojha, S., & Mitchell, E. J. (2023). Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom. Acta Paediatrica, https://doi.org/10.1111/apa.16795

Aim: To explore the attitudes of parents and healthcare professionals (HCPs), and facilitators and barrier to implementation of Kangaroo Care (KC) in the United Kingdom. Methods: Online cross-sectional survey; distributed via the British Association... Read More about Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom.

Observational cohort study of use of caffeine in preterm infants and association between early caffeine use and neonatal outcomes (2023)
Journal Article
Szatkowski, L., Fateh, S., Abramson, J., Kwok, T. C., Sharkey, D., Budge, H., & Ojha, S. (2023). Observational cohort study of use of caffeine in preterm infants and association between early caffeine use and neonatal outcomes. Archives of Disease in Childhood. Fetal and Neonatal Edition, 108(5), 505-510. https://doi.org/10.1136/archdischild-2022-324919

Objective: To quantify trends in caffeine use in infants born at

Breastfeeding in infants diagnosed with phenylketonuria (2022)
Journal Article
Chong, L., Kalvala, J., Chadborn, N., & Ojha, S. (2022). Breastfeeding in infants diagnosed with phenylketonuria. Cochrane Database of Systematic Reviews, 2022(8), 1-11. https://doi.org/10.1002/14651858.CD015243

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of breastfeeding (exclusive or partial) compared to low-Phe formula feeding in the first six months after birth in infants diag... Read More about Breastfeeding in infants diagnosed with phenylketonuria.

Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice? (2022)
Journal Article
Ojha, S., Abramson, J., & Dorling, J. (2022). Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?. BMJ Paediatrics Open, 6(1), Article e001460. https://doi.org/10.1136/bmjpo-2022-001460

Mechanical ventilation is an uncomfortable and potentially painful intervention. Opioids, such as morphine and fentanyl, are used for analgesia and sedation but there is uncertainty whether they reduce pain in mechanically ventilated infants. Moreove... Read More about Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?.

The natural history of ataxia-telangiectasia (A-T): A systematic review (2022)
Journal Article
Petley, E., Yule, A., Alexander, S., Ojha, S., & Whitehouse, W. P. (2022). The natural history of ataxia-telangiectasia (A-T): A systematic review. PLoS ONE, 17(3), Article e0264177. https://doi.org/10.1371/journal.pone.0264177

Background: Ataxia-telangiectasia is an autosomal recessive, multi-system, and life-shortening disease caused by mutations in the ataxia-telangiectasia mutated gene. Although widely reported, there are no studies that give a comprehensive picture of... Read More about The natural history of ataxia-telangiectasia (A-T): A systematic review.

Daily Bread: Women’s Self-Help Microfinance and the Social Meanings of Money (2022)
Journal Article
Bott, E., Ojha, S., Mini, S., Smyth, A. R., Kamal Kumar, R., Choudhary, S., & Yaron, G. (2023). Daily Bread: Women’s Self-Help Microfinance and the Social Meanings of Money. Sociological Research Online, 28(2), 442-461. https://doi.org/10.1177/13607804211058745

In this article, we explore the impacts and implications of ‘Rojiroti’, a women’s self-help group (SHG) microfinance scheme operating in poor communities in Bihar, India. We focus particularly on how improvements found in women’s circumstances and in... Read More about Daily Bread: Women’s Self-Help Microfinance and the Social Meanings of Money.

Drug utilisation in neonatal units in England and Wales: a national cohort study (2022)
Journal Article
Al-Turkait, A., Szatkowski, L., Choonara, I., & Ojha, S. (2022). Drug utilisation in neonatal units in England and Wales: a national cohort study. European Journal of Clinical Pharmacology, 78(4), 669-677. https://doi.org/10.1007/s00228-021-03267-x

Purpose: To describe drug utilisation patterns in neonatal units. Methods: Retrospective observational cohort study using data held in the National Neonatal Research Database (NNRD) for neonatal units in England and Wales including infants born at 23... Read More about Drug utilisation in neonatal units in England and Wales: a national cohort study.

Anti-reflux medication use in preterm infants (2021)
Journal Article
Binti Abdul Hamid, H., Szatkowski, L., Budge, H., & Ojha, S. (2022). Anti-reflux medication use in preterm infants. Pediatric Research, 92, 520-525. https://doi.org/10.1038/s41390-021-01821-y

Background: Current recommendations do not support the use of anti-reflux medications to treat gastro-oesophageal reflux disease (GORD) among preterm infants. Objective: To describe the prevalence of GORD and the use of anti-reflux medications amongs... Read More about Anti-reflux medication use in preterm infants.

Observational cohort study of changing trends in non-invasive ventilation in very preterm infants and associations with clinical outcomes (2021)
Journal Article
Sand, L., Szatkowski, L., Kwok, T. C., Sharkey, D., Todd, D. A., Budge, H., & Ojha, S. (2022). Observational cohort study of changing trends in non-invasive ventilation in very preterm infants and associations with clinical outcomes. Archives of Disease in Childhood. Fetal and Neonatal Edition, 107(2), 150-155. https://doi.org/10.1136/archdischild-2021-322390

Objective: To determine the change in non-invasive ventilation (NIV) use over time in infants born at

Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study (2021)
Journal Article
Servante, J., Abramson, J., Walker, K. F., & Ojha, S. (2021). Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study. Breastfeeding Medicine, 16(5), 407-413. https://doi.org/10.1089/bfm.2020.0071

Objective: To investigate the association, in the United Kingdom, between having an episiotomy during childbirth and giving human milk by any modality as an infant's first feed. We also identified maternal demographic factors and perinatal experience... Read More about Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study.

Feeding during neonatal therapeutic hypothermia, assessed using routinely collected National Neonatal Research Database data: a retrospective, UK population-based cohort study (2021)
Journal Article
Gale, C., Longford, N. T., Jeyakumaran, D., Ougham, K., Battersby, C., Ojha, S., & Dorling, J. (2021). Feeding during neonatal therapeutic hypothermia, assessed using routinely collected National Neonatal Research Database data: a retrospective, UK population-based cohort study. Lancet Child and Adolescent Health, 5(6), 408-416. https://doi.org/10.1016/S2352-4642%2821%2900026-2

Background: Therapeutic hypothermia is standard of care in high-income countries for babies born with signs of hypoxic ischaemic encephalopathy, but optimal feeding during treatment is uncertain and practice is variable. This study aimed to assess th... Read More about Feeding during neonatal therapeutic hypothermia, assessed using routinely collected National Neonatal Research Database data: a retrospective, UK population-based cohort study.

Feasibility of using an Early Warning Score for preterm or low birthweight infants in a low-resource setting: Results of a mixed-methods study at a national referral hospital in Kenya (2020)
Journal Article
Mitchell, E. J., Qureshi, Z., Were, F., Daniels, J., Gwako, G., Osoti, A., …Ojha, S. (2020). Feasibility of using an Early Warning Score for preterm or low birthweight infants in a low-resource setting: Results of a mixed-methods study at a national referral hospital in Kenya. BMJ Open, 10(10), Article e039061. https://doi.org/10.1136/bmjopen-2020-039061

© 2020 BMJ Publishing Group. All rights reserved. Introduction Fifteen million babies are born prematurely, before 37 weeks gestational age, globally. More than 80% of these are in sub-Saharan Africa and Asia. 35% of all deaths in the first month o... Read More about Feasibility of using an Early Warning Score for preterm or low birthweight infants in a low-resource setting: Results of a mixed-methods study at a national referral hospital in Kenya.

Education of family members to support weaning to solids and nutrition in later infancy in term-born infants (2020)
Journal Article
Ojha, S., Elfzzani, Z., Kwok, T. C., & Dorling, J. (2020). Education of family members to support weaning to solids and nutrition in later infancy in term-born infants. Cochrane Database of Systematic Reviews, 2020(7), Article CD012241. https://doi.org/10.1002/14651858.cd012241.pub2

Review question We reviewed the evidence for effects of nutrition education about appropriate feeding practices during weaning on growth and development in children born at term gestation. Background Around the world, over 150 million childr... Read More about Education of family members to support weaning to solids and nutrition in later infancy in term-born infants.