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All Outputs (7)

Apparent diffusion coefficient for genetic characterisation of untreated adult gliomas: a meta-analysis stratified by methods (2025)
Journal Article
Bhatti, F., Strobel, J., Tench, C., Grech-Sollars, M., A Dineen, R., Sollmann, N., & Thust, S. (2025). Apparent diffusion coefficient for genetic characterisation of untreated adult gliomas: a meta-analysis stratified by methods. Neuro-Oncology Advances, Article vdaf103. https://doi.org/10.1093/noajnl/vdaf103

Background

Isocitrate dehydrogenase (IDH) mutation and chromosome 1p19q genotyping have become fundamental to the prognostic grouping of adult diffuse gliomas. Apparent diffusion coefficient (ADC) values may enable non-invasive prediction of gliom... Read More about Apparent diffusion coefficient for genetic characterisation of untreated adult gliomas: a meta-analysis stratified by methods.

Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis (2025)
Journal Article
Allen, C. M., Clarke, M. A., Pai, H. V., Cauchi, M., Hawken, J., Htet, Z. M., Allen-Philbey, K., Mohamed, B., Fitzsimmons, D., Das Nair, R., Morgan, P., Partlett, C., Dineen, R. A., Schmierer, K., Tallantyre, E. C., & Evangelou, N. (2025). Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis. Neurology Open Access, 1(2), Article e000017. https://doi.org/10.1212/WN9.0000000000000017

Background and Objectives
The central vein sign (CVS) describes the presence of venules within multiple sclerosis (MS) brain lesions, visible on T2*-weighted MRI. In the upcoming revision of the MS diagnostic criteria, the simplified “rule of 6” (i.... Read More about Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis.

T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI (2025)
Journal Article
Marshall, M., Aphiwatthanasumet, K., Mougin, O., Stadelmann, C., Morgan, P. S., Dineen, R. A., Gowland, P., Evangelou, N., & Clarke, M. A. (2025). T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI. Journal of Neuroimaging, 35(3), Article e70044. https://doi.org/10.1111/jon.70044

Background and Purpose:
Chronic active multiple sclerosis (MS) lesions represent a particularly destructive subset of lesions on pathology. However, their imaging correlates, including paramagnetic rim lesions (PRLs) detected on susceptibility-weig... Read More about T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI.

White Matter Microstructural Alterations in Type 2 Diabetes: A Combined UK Biobank Study of Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging (2025)
Journal Article
Alotaibi, A., Alqarras, M., Podlasek, A., Almanaa, A., AlTokhis, A., Aldhebaib, A., Aldebasi, B., Almutairi, M., Tench, C. R., Almanaa, M., Mohammadi-Nejad, A.-R., Constantinescu, C. S., Dineen, R. A., & Lee, S. (2025). White Matter Microstructural Alterations in Type 2 Diabetes: A Combined UK Biobank Study of Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging. Medicina, 61(3), Article 455. https://doi.org/10.3390/medicina61030455

Background and objectives:

Type 2 diabetes mellitus (T2DM) affects brain white matter microstructure. While diffusion tensor imaging (DTI) has been used to study white matter abnormalities in T2DM, it lacks specificity for complex white matter tr... Read More about White Matter Microstructural Alterations in Type 2 Diabetes: A Combined UK Biobank Study of Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging.

Magnetic Resonance Imaging of Inner Ear and Internal Auditory Canal Structures in the Presence of a Cochlear Implant (2025)
Journal Article
Dewey, R. S., Dineen, R. A., Clemence, M., Menon, N., Bowtell, R., Boyle, P., & Hartley, D. E. H. (2025). Magnetic Resonance Imaging of Inner Ear and Internal Auditory Canal Structures in the Presence of a Cochlear Implant. Otology and Neurotology, 46(4), e105-e108. https://doi.org/10.1097/mao.0000000000004445

Objective
To determine whether the internal auditory canal (IAC) can be visualized using magnetic resonance imaging (MRI) in users of a cochlear implant (CI) model that can safely undergo MRI at 3 T.

Patients
Four normally hearing controls and... Read More about Magnetic Resonance Imaging of Inner Ear and Internal Auditory Canal Structures in the Presence of a Cochlear Implant.

Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI (2025)
Journal Article
Sundaresan, V., Zamboni, G., Dineen, R. A., Auer, D. P., Sotiropoulos, S. N., Sprigg, N., Jenkinson, M., & Griffanti, L. (2025). Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI. European Radiology Experimental, 9(1), Article 5. https://doi.org/10.1186/s41747-024-00544-z

Cerebral microbleeds (CMBs) are small, hypointense hemosiderin deposits in the brain measuring 2–10 mm in diameter. As one of the important biomarkers of small vessel disease, they have been associated with various neurodegenerative and cerebrovascul... Read More about Automated characterisation of cerebral microbleeds using their size and spatial distribution on brain MRI.