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Barriers to diagnosing and treating vulval lichen sclerosus: a survey study (2024)
Journal Article
Crew, A., Leatherland, R., Clarke, L., Owen, C., & Simpson, R. (2024). Barriers to diagnosing and treating vulval lichen sclerosus: a survey study. British Journal of General Practice, https://doi.org/10.3399/BJGP.2024.0360

Background
Vulval lichen sclerosus (VLS) is a chronic inflammatory condition that is frequently misdiagnosed and under-recognised. To date, qualitative research focuses on lived experience of VLS, with women attributing diagnostic delay to poor int... Read More about Barriers to diagnosing and treating vulval lichen sclerosus: a survey study.

Expert opinion on characteristics of vulval LS: initial identification of important clinical features through an international electronic-Delphi consensus study (2024)
Journal Article
Simpson, R. C., Birchall, M., Daniels, J., Gran, S., Kirtschig, G., & Thomas, K. S. (2024). Expert opinion on characteristics of vulval LS: initial identification of important clinical features through an international electronic-Delphi consensus study. Clinical and Experimental Dermatology, Article llae393. https://doi.org/10.1093/ced/llae393

Background
Lichen sclerosus (LS) is a chronic inflammatory condition mainly affecting genital skin. It causes distressing symptoms that impact daily quality of life as well as progressive anatomical changes and potential risk of cancer. Vulval LS is... Read More about Expert opinion on characteristics of vulval LS: initial identification of important clinical features through an international electronic-Delphi consensus study.

The critical role of technologies in neonatal care (2023)
Journal Article
Taha, S., Simpson, R. B., & Sharkey, D. (2023). The critical role of technologies in neonatal care. Early Human Development, 187, Article 105898. https://doi.org/10.1016/j.earlhumdev.2023.105898

Neonatal care has made significant advances in the last few decades. As a result, mortality and morbidity in high-risk infants, such as extremely preterm infants or those infants with birth-related brain injury, has reduced significantly. Many of the... Read More about The critical role of technologies in neonatal care.

Is urinary incontinence associated with vulval lichen sclerosus in females? A cross‐sectional study (2021)
Journal Article
Kirby, L., Gran, S., Orekoya, F., Owen, C., & Simpson, R. (2021). Is urinary incontinence associated with vulval lichen sclerosus in females? A cross‐sectional study. British Journal of Dermatology, 185(5), 1063-1065. https://doi.org/10.1111/bjd.20583

Increasing evidence suggests the pathogenesis of male genital lichen sclerosus (LS) is driven by chronic, occluded exposure of susceptible epithelium to the irritant effect of urine (1, 2). It is not clear how this can be extrapolated to females, how... Read More about Is urinary incontinence associated with vulval lichen sclerosus in females? A cross‐sectional study.

Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base (2021)
Journal Article
Tasker, F., Kirby, L., Grindlay, D. J. C., Lewis, F., & Simpson, R. C. (2021). Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base. Skin Health and Disease, 1(3), Article e52. https://doi.org/10.1002/ski2.52

Background

Lichen sclerosus (LS) is a chronic, inflammatory dermatosis. Initial treatment with superpotent topical corticosteroids is the accepted and evidence-based first-line therapy. For those who do not respond after exclusion of other potenti... Read More about Laser therapy for genital lichen sclerosus: A systematic review of the current evidence base.

Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta‐analysis (2021)
Journal Article
Kirby, L., Gran, S., Kreuser-Genis, I., Owen, C., & Simpson, R. (2021). Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta‐analysis. Skin Health and Disease, 1(1), Article e13. https://doi.org/10.1002/ski2.13

Background
Lichen sclerosus (LS) is a scarring chronic inflammatory disease with a predilection for genital skin in both sexes. The aetiology of LS is controversial, but evidence increasingly suggests that the occluded exposure of susceptible epith... Read More about Is urinary incontinence associated with lichen sclerosus in females? A systematic review and meta‐analysis.

Outcome domains in lichen sclerosus (2020)
Journal Article
Goodrum, C., Leighton, P., & Simpson, R. (2020). Outcome domains in lichen sclerosus. British Journal of Dermatology, 183(5), 966-968. https://doi.org/10.1111/bjd.19253

Lichen Sclerosus (LS) is a chronic inflammatory dermatosis predominantly affecting the genitals. It can affect men, women and children. LS affecting female genitalia typically presents with itchy patches that impact on physical and psychosocial‐sexua... Read More about Outcome domains in lichen sclerosus.

Benign skin diseases affecting the vulva (2019)
Journal Article
Kirby, L., Simpson, R., & Nunns, D. (2019). Benign skin diseases affecting the vulva. Obstetrics, Gynaecology and Reproductive Medicine, 29(9), 264-270. https://doi.org/10.1016/j.ogrm.2019.05.004

Vulval skin disease is common in gynaecological practice. This review aims to enhance clinical skills in patient assessment, vulval examination and treatment of common benign vulval skin disease illustrated through cases. Although simple treatments a... Read More about Benign skin diseases affecting the vulva.

Living with vulval lichen sclerosus: a systematic review (2019)
Journal Article
Rees, S., Kirby, L., & Simpson, R. (2019). Living with vulval lichen sclerosus: a systematic review. British Journal of Dermatology, 180(6), 1555-1556. https://doi.org/10.1111/bjd.17790

Lichen sclerosus (LS) is an under‐researched disorder, particularly from the perspective of individuals who have the condition. A recent James Lind Alliance Priority Setting Partnership identified uncertainties in many aspects of the condition, inclu... Read More about Living with vulval lichen sclerosus: a systematic review.

Future research priorities for lichen sclerosus – results of a James Lind Alliance Priority Setting Partnership (2019)
Journal Article
Simpson, R., Cooper, S., Kirtschig, G., Larsen, S., Lawton, S., McPhee, M., Murphy, R., Nunns, D., Rees, S., Tarpey, M., Thomas, K., & Lichen Sclerosus Priority Setting Partnership Steering Group. (2019). Future research priorities for lichen sclerosus – results of a James Lind Alliance Priority Setting Partnership. British Journal of Dermatology, 180(5), 1236-1237. https://doi.org/10.1111/bjd.17447

Help for Future Research: Lessons Learned in Trial Design, Recruitment, and Delivery From the “hELP” Study (2018)
Journal Article
Simpson, R. C., Murphy, R., Bratton, D. J., Sydes, M. R., Wilkes, S., Nankervis, H., Dowey, S., Bell, H., Cruickshank, M. E., Gibbon, K., Green, C. M., Wong, C., Owen, C. M., London, K., Haque, S., & Thomas, K. S. (2018). Help for Future Research: Lessons Learned in Trial Design, Recruitment, and Delivery From the “hELP” Study. Journal of Lower Genital Tract Disease, 22(4), 405-408. https://doi.org/10.1097/LGT.0000000000000407

Skin diseases affecting the vulva (2017)
Journal Article
Simpson, R., & Nunns, D. (2017). Skin diseases affecting the vulva. Obstetrics, Gynaecology and Reproductive Medicine, 27(3), 77-85. https://doi.org/10.1016/j.ogrm.2016.12.007

Vulval skin disease is common in gynaecological practice. This article aims to enhance clinical skills in patient assessment, vulval examination and treatment of common benign vulval skin disease. Basic treatments are often of benefit the patient (e.... Read More about Skin diseases affecting the vulva.