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All Outputs (5)

Highly porous polycaprolactone microspheres for skeletal repair promote a mature bone cell phenotype in vitro (2024)
Journal Article
Paterson, T. E., Owen, R., Sherborne, C., Bahmaee, H., Harding, A. L., Green, N. H., Reilly, G. C., & Claeyssens, F. (2024). Highly porous polycaprolactone microspheres for skeletal repair promote a mature bone cell phenotype in vitro. Journal of Materials Chemistry B, https://doi.org/10.1039/d4tb01532k

Improving our ability to treat skeletal defects is a critical medical challenge that necessitates the development of new biomaterials. One promising approach involves the use of degradable polymer microparticles with an interconnected internal porosi... Read More about Highly porous polycaprolactone microspheres for skeletal repair promote a mature bone cell phenotype in vitro.

Computer Vision for Substrate Detection in High‐Throughput Biomaterial Screens Using Bright‐Field Microscopy (2024)
Journal Article
Owen, R., Nasir, A., H. Amer, M., Nie, C., Xue, X., Burroughs, L., Denning, C., D. Wildman, R., A. Khan, F., R. Alexander, M., & R. A. J. Rose, F. (2024). Computer Vision for Substrate Detection in High‐Throughput Biomaterial Screens Using Bright‐Field Microscopy. Advanced Intelligent Systems, Article 2400573. https://doi.org/10.1002/aisy.202400573

High-throughput screening (HTS) can be used when ab initio information is unavailable for rational design of new materials, generating data on properties such as chemistry and topography that control cell behavior. Biomaterial screens are typically f... Read More about Computer Vision for Substrate Detection in High‐Throughput Biomaterial Screens Using Bright‐Field Microscopy.

β-glycerophosphate, not low magnitude fluid shear stress, increases osteocytogenesis in the osteoblast-to-osteocyte cell line IDG-SW3 (2024)
Journal Article
Owen, R., Wittkowske, C., Lacroix, D., Perrault, C. M., & Reilly, G. C. (2024). β-glycerophosphate, not low magnitude fluid shear stress, increases osteocytogenesis in the osteoblast-to-osteocyte cell line IDG-SW3. Connective Tissue Research, https://doi.org/10.1080/03008207.2024.2375065

Aim
As osteoblasts deposit a mineralized collagen network, a subpopulation of these cells differentiates into osteocytes. Biochemical and mechanical stimuli, particularly fluid shear stress (FSS), are thought to regulate this, but their relative inf... Read More about β-glycerophosphate, not low magnitude fluid shear stress, increases osteocytogenesis in the osteoblast-to-osteocyte cell line IDG-SW3.

Glycerol-based sustainably sourced resin for volumetric printing (2024)
Journal Article
Krumins, E., Lentz, J. C., Sutcliffe, B., Sohaib, A., Jacob, P. L., Brugnoli, B., …Taresco, V. (2024). Glycerol-based sustainably sourced resin for volumetric printing. Green Chemistry, 26(3), 1345-1355. https://doi.org/10.1039/d3gc03607c

Volumetric Additive Manufacturing (VAM) represents a revolutionary advancement in the field of Additive Manufacturing, as it allows for the creation of objects in a single, cohesive process, rather than in a layer-by-layer approach. This innovative t... Read More about Glycerol-based sustainably sourced resin for volumetric printing.

Engineering periodontal tissue interfaces using multiphasic scaffolds and membranes for guided bone and tissue regeneration (2023)
Journal Article
Ozkendir, O., Karaca, I., Cullu, S., Erdoğan, O. C., Yaşar, H. N., Dikici, S., …Aldemir Dikici, B. (2024). Engineering periodontal tissue interfaces using multiphasic scaffolds and membranes for guided bone and tissue regeneration. Biomaterials Advances, 157, Article 213732. https://doi.org/10.1016/j.bioadv.2023.213732

Periodontal diseases are one of the greatest healthcare burdens worldwide. The periodontal tissue compartment is an anatomical tissue interface formed from the periodontal ligament, gingiva, cementum, and bone. This multifaceted composition makes tis... Read More about Engineering periodontal tissue interfaces using multiphasic scaffolds and membranes for guided bone and tissue regeneration.