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All Outputs (88)

The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey (2021)
Journal Article
Andrews, J. A., Craven, M. P., Lang, A. R., Guo, B., Morriss, R., Hollis, C., & The RADAR-CNS Consortium. (2021). The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey. BMC Medical Informatics and Decision Making, 21, Article 282. https://doi.org/10.1186/s12911-021-01640-5

Background: A variety of smartphone apps and wearables are available both to help patients monitor their health and to support health care professionals (HCPs) in providing clinical care. As part of the RADAR-CNS consortium, we have conducted researc... Read More about The impact of data from remote measurement technology on the clinical practice of healthcare professionals in depression, epilepsy and multiple sclerosis: survey.

The predictive value of patient, therapist, and in‐session ratings of motivational factors early in remote cognitive behavioural therapy for severe health anxiety (2021)
Journal Article
Malins, S., Moghaddam, N., Morriss, R., Schröder, T., Brown, P., & Boycott, N. (2022). The predictive value of patient, therapist, and in‐session ratings of motivational factors early in remote cognitive behavioural therapy for severe health anxiety. British Journal of Clinical Psychology, 61(2), 364-384. https://doi.org/10.1111/bjc.12328

Objectives. Remote psychotherapy and the prevalence of Severe Health Anxiety (SHA) are both growing as a result of the COVID-19 pandemic. Remotely delivered Cognitive Behavioural Therapy (rCBT) for SHA is evidenced as effective, but many who seek hel... Read More about The predictive value of patient, therapist, and in‐session ratings of motivational factors early in remote cognitive behavioural therapy for severe health anxiety.

Screening male prisoners for depression and anxiety with the PHQ-9 and GAD-7 at NHS Healthcheck: patterns of symptoms and caseness threshold (2021)
Journal Article
Butcher, E., Packham, C., Williams, M., Miksza, J., Kaul, A., Khunti, K., & Morriss, R. (2021). Screening male prisoners for depression and anxiety with the PHQ-9 and GAD-7 at NHS Healthcheck: patterns of symptoms and caseness threshold. BMC Psychiatry, 21(1), Article 446. https://doi.org/10.1186/s12888-021-03453-2

Background: Screening for depression and anxiety disorders has been proposed in prison populations but little is known about caseness thresholds on commonly used self-report measures in relation to core symptoms, risk factors and symptom patterns. Me... Read More about Screening male prisoners for depression and anxiety with the PHQ-9 and GAD-7 at NHS Healthcheck: patterns of symptoms and caseness threshold.

Mental health and other factors associated with work productivity after injury in the UK: multicentre cohort study (2021)
Journal Article
Kellezi, B., Dhiman, P., Coupland, C., Whitehead, J., Morriss, R., Joseph, S., …Kendrick, D. (2022). Mental health and other factors associated with work productivity after injury in the UK: multicentre cohort study. Injury Prevention, 28(2), 131-140. https://doi.org/10.1136/injuryprev-2021-044311

Introduction: Mental health conditions are a major contributor to productivity loss and are common post-injury. This study quantifies post-injury productivity loss and its association with pre and post-injury mental health, injury, demographic, healt... Read More about Mental health and other factors associated with work productivity after injury in the UK: multicentre cohort study.

Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial (2021)
Journal Article
Morriss, R., Kaylor-Hughes, C., Rawsthorne, M., Coulson, N., Simpson, S., Guo, B., …Williams, L. (2021). Correction: A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial. Journal of Medical Internet Research, 23(7), Article e31543. https://doi.org/10.2196/31543

[This corrects the article DOI: 10.2196/23487.].

Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register (2021)
Journal Article
Garjani, A., Hunter, R., Law, G. R., Middleton, R. M., Tuite-Dalton, K. A., Dobson, R., …das Nair, R. (2022). Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register. Multiple Sclerosis Journal, 28(7), 1060-1071. https://doi.org/10.1177/13524585211020435

Background: People with MS (pwMS) have had higher rates of anxiety and depression than the general population before the COVID-19 pandemic, placing them at higher risk of experiencing poor psychological wellbeing during the pandemic. Objective: To as... Read More about Mental health of people with multiple sclerosis during the COVID-19 outbreak: A prospective cohort and cross-sectional case–control study of the UK MS Register.

The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time (2021)
Journal Article
Guo, B., Li, L., Crawford, M. J., & Morriss, R. (2021). The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time. International Journal of Methods in Psychiatric Research, 30(3), Article e1874. https://doi.org/10.1002/mpr.1874

Objectives

There is a lack of independent longitudinal evidence on the factor structure and validity of the Zanarini Rating Scale for Borderline Personality Disorder (ZAN‐BPD). This study aimed to investigate the dimensionality of ZAN‐BPD and its... Read More about The factor structure of the Zanarini Rating Scale for Borderline Personality Disorder: Exploratory Structural Equation Modelling and measurement invariance over time.

A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial (2021)
Journal Article
Rawsthorne, M., Tata, L., Williams, L., Morriss, R., Guo, B., Simpson, S., …Moran, P. (2021). A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial. Journal of Medical Internet Research, 23(4), Article e23487. https://doi.org/10.2196/23487

Background: Effective help for depression and anxiety reaches a small proportion of people who might benefit from it. The scale of the problem suggests the need for effective, safe web-based public health services delivered directly to the public. On... Read More about A direct-to-public peer support program (Big White Wall) versus web-based information to aid the self-management of depression and anxiety: Results and challenges of an automated randomized controlled trial.

The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial (2021)
Journal Article
Browning, M., Bilderbeck, A. C., Dias, R., Dourish, C. T., Kingslake, J., Deckert, J., …Dawson, G. R. (2021). The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial. Neuropsychopharmacology, 46, 1307–1314. https://doi.org/10.1038/s41386-021-00981-z

Depressed patients often do not respond to the first antidepressant prescribed, resulting in sequential trials of different medications. Personalised medicine offers a means of reducing this delay, however the clinical effectiveness of personalised a... Read More about The Clinical Effectiveness of Using a Predictive Algorithm to Guide Antidepressant Treatment in Primary Care (PReDicT): an open-label, randomised controlled trial.

PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression (2021)
Preprint / Working Paper
Joseph, R. M., Jack, R. H., Morriss, R., Knaggs, R. D., Hollis, C., Hippisley-Cox, J., & Coupland, C. PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression

This protocol describes a cohort study comparing the risks of mortality and serious self-harm (suicide or near-fatal deliberate self-harm) between adults with depression prescribed mirtazapine, a selective serotonin reuptake inhibitor (SSRI), amitrip... Read More about PROTOCOL: A cohort study examining the association between mirtazapine and mortality risk in adults with a diagnosis of depression.

Vocational rehabilitation to enhance return to work after trauma (ROWTATE): protocol for a non-randomised single-arm mixed-methods feasibility study (2021)
Journal Article
Kendrick, D., das Nair, R., Kellezi, B., Morriss, R., Kettlewell, J., Holmes, J., …Radford, K. (2021). Vocational rehabilitation to enhance return to work after trauma (ROWTATE): protocol for a non-randomised single-arm mixed-methods feasibility study. Pilot and Feasibility Studies, 7(1), Article 29. https://doi.org/10.1186/s40814-021-00769-4

Background
Traumatic injuries are common amongst working age adults. Survivors often experience physical and psychological problems, reduced quality of life and difficulty returning to work. Vocational rehabilitation improves work outcomes for a ran... Read More about Vocational rehabilitation to enhance return to work after trauma (ROWTATE): protocol for a non-randomised single-arm mixed-methods feasibility study.

Informing the Development of a Digital Health Platform Through Universal Points of Care: Qualitative Survey Study (2020)
Journal Article
Craven, M. P., Andrews, J., Lang, A. R., Simblett, S. K., Bruce, S., Thorpe, S., …The RADAR-CNS Consortium. (2020). Informing the Development of a Digital Health Platform Through Universal Points of Care: Qualitative Survey Study. JMIR Formative Research, 4(11), Article e22756. https://doi.org/10.2196/22756

Background: Epilepsy, multiple sclerosis (MS), and depression are chronic conditions where technology holds potential in clinical monitoring and self-management. Over 5 years, the Remote Assessment of Disease and Relapse-Central Nervous System (RADAR... Read More about Informing the Development of a Digital Health Platform Through Universal Points of Care: Qualitative Survey Study.

NHS Health Check Programme: a qualitative study of prison experience (2020)
Journal Article
THOMSON, L., Williams, M., Butcher, E., Morriss, R., Kunti, K., & Packham, C. (2022). NHS Health Check Programme: a qualitative study of prison experience. Journal of Public Health, 44(1), 174-183. https://doi.org/10.1093/pubmed/fdaa189

Background: NHS Health Checks began in England in 2009 and were subsequently introduced into English prisons. Uptake has been patchy and there is limited understanding about factors that may limit or enhance uptake in prison settings. Uptake of this... Read More about NHS Health Check Programme: a qualitative study of prison experience.

The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome (2020)
Journal Article
Nixon, N., Guo, B., Garland, A., Kaylor-Hughes, C., Nixon, E., & Morriss, R. (2020). The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome. PLoS ONE, 15(10), Article e0241370. https://doi.org/10.1371/journal.pone.0241370

Background:
The 17-item Hamilton Depression Rating Scale (HDRS17) is used world-wide as an observer-rated measure of depression in randomised controlled trials (RCTs) despite continued uncertainty regarding its factor structure. This study investiga... Read More about The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome.

Preventive digital mental health interventions for children and young people: a review of the design and reporting of research (2020)
Journal Article
Bergin, A. D., Vallejos, E. P., Davies, E. B., Daley, D., Ford, T., Harold, G., …Hollis, C. (2020). Preventive digital mental health interventions for children and young people: a review of the design and reporting of research. npj Digital Medicine, 3(1), Article 133. https://doi.org/10.1038/s41746-020-00339-7

Digital health interventions (DHIs) have frequently been highlighted as one way to respond to increasing levels of mental health problems in children and young people. Whilst many are developed to address existing mental health problems, there is als... Read More about Preventive digital mental health interventions for children and young people: a review of the design and reporting of research.

Differential effects of cranial electrotherapy stimulation on changes in anxiety and depression symptoms over time in patients with generalized anxiety disorder (2020)
Journal Article
Morriss, R., & Price, L. (2020). Differential effects of cranial electrotherapy stimulation on changes in anxiety and depression symptoms over time in patients with generalized anxiety disorder. Journal of Affective Disorders, 277, 785-788. https://doi.org/10.1016/j.jad.2020.09.006

Background
Cranial electrotherapy stimulation (CES) is a safe and well-tolerated 6-12 week treatment that is clinically and cost effective on both anxiety and depression symptoms resulting in sustained remission of these symptoms at 12 and 24 weeks... Read More about Differential effects of cranial electrotherapy stimulation on changes in anxiety and depression symptoms over time in patients with generalized anxiety disorder.

Health Care Professionals’ Views on Using Remote Measurement Technology in Managing Central Nervous System Disorders: Qualitative Interview Study (2020)
Journal Article
Andrews, J. A., Craven, M. P., Jamnadas-Khoda, J., Lang, A. R., Morriss, R., Hollis, C., & The RADAR-CNS Consortium. (2020). Health Care Professionals’ Views on Using Remote Measurement Technology in Managing Central Nervous System Disorders: Qualitative Interview Study. Journal of Medical Internet Research, 22(7), Article e17414. https://doi.org/10.2196/17414

Background: Remote measurement technologies (RMT) can be used to collect data on a variety of bio-behavioral variables, which may improve the care of patients with central nervous system disorders. Although various studies have explored their potenti... Read More about Health Care Professionals’ Views on Using Remote Measurement Technology in Managing Central Nervous System Disorders: Qualitative Interview Study.

The Acceptability and Usability of Digital Health Interventions for Adults with Depressive, Anxiety and Somatoform Disorders: A Qualitative Systematic Review and Meta-synthesis (2020)
Journal Article
Patel, S., Akhtar, A., Malins, S., Wright, N., Rowley, E., Young, E., …Morriss, R. (2020). The Acceptability and Usability of Digital Health Interventions for Adults with Depressive, Anxiety and Somatoform Disorders: A Qualitative Systematic Review and Meta-synthesis. Journal of Medical Internet Research, 22(7), Article e16228. https://doi.org/10.2196/16228

Background: The prevalence of mental health disorders continues to rise, with almost 4% of the world population having an anxiety disorder and almost 3.5% having depression in 2017. Despite the high prevalence, only one-third of people with depressio... Read More about The Acceptability and Usability of Digital Health Interventions for Adults with Depressive, Anxiety and Somatoform Disorders: A Qualitative Systematic Review and Meta-synthesis.

Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study (2020)
Journal Article
Jack, R. H., Hollis, C., Coupland, C., Morriss, R., Knaggs, R. D., Butler, D., …Hippisley-Cox, J. (2020). Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study. PLoS Medicine, 17(7), Article e1003215. https://doi.org/10.1371/journal.pmed.1003215

BACKGROUND: The use of antidepressants in children and adolescents remains controversial. We examined trends over time and variation in antidepressant prescribing in children and young people in England and whether the drugs prescribed reflected UK l... Read More about Incidence and prevalence of primary care antidepressant prescribing in children and young people in England, 1998-2017: A population-based cohort study.