All Outputs (2)

Actin depolymerization is associated with meiotic acceleration in cycloheximide-treated ovine oocytes (2015)
Journal Article
German, S. D., Lee, J.-H., Campbell, K. H., Sweetman, D., & Alberio, R. (in press). Actin depolymerization is associated with meiotic acceleration in cycloheximide-treated ovine oocytes. Biology of Reproduction, 92(4), https://doi.org/10.1095/biolreprod.114.122341

Oocytes treated with the protein synthesis inhibitor cycloheximide (CHX) arrest at the germinal vesicle (GV) stage and undergo accelerated GV breakdown (GVBD) after CHX is removed. However, little is known about the underlying mechanism of accelerate... Read More about Actin depolymerization is associated with meiotic acceleration in cycloheximide-treated ovine oocytes.

Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer (2015)
Journal Article
German, S. D., Campbell, K. H., Thornton, E., McLachlan, G., Sweetman, D., & Alberio, R. (2015). Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer. Cellular Reprogramming, 17(1), https://doi.org/10.1089/cell.2014.0071

Induced pluripotent stem cells (iPSCs) share similar characteristics of indefinite in vitro growth with embryonic stem cells (ESCs) and may therefore serve as a useful tool for the targeted genetic modification of farm animals via nuclear transfer (N... Read More about Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer.