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TNF and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein (2010)
Journal Article
Clarke, D. L., Clifford, R. L., Jindarat, S., Proud, D., Pang, L., Belvisi, M., & Knox, A. J. (2010). TNF and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein. Journal of Biological Chemistry, 285(38), 29101-29110. https://doi.org/10.1074/jbc.m109.0999952

Asthmatic airway smooth muscle (ASM) expresses interferon-γ-inducible protein-10 (CXCL10), a chemokine known to mediate mast cell migration into ASM bundles that has been reported in the airways of asthmatic patients. CXCL10 is elevated in patients s... Read More about TNF and IFN  Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF- B, and the Transcriptional Coactivator CREB-binding Protein.

Vitamin D - a new treatment for airway remodelling in asthma? (2009)
Journal Article
Clifford, R. L., & Knox, A. J. (2009). Vitamin D - a new treatment for airway remodelling in asthma?. British Journal of Pharmacology, 158(6), 1426-1428. https://doi.org/10.1111/j.1476-5381.2009.00429.x

Increased airway smooth muscle (ASM) mass plays a critical role in chronic asthmatic airway remodelling. ASM cell hypertrophy and hyperplasia are likely to contribute to increased ASM mass and a variety of mitogens induce ASM proliferation in cell cu... Read More about Vitamin D - a new treatment for airway remodelling in asthma?.

Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor β1: REQUIREMENT FOR Smads,β-CATENIN, AND GSK3β (2008)
Journal Article
Clifford, R. L., Deacon, K., & Knox, A. J. (2008). Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor β1: REQUIREMENT FOR Smads,β-CATENIN, AND GSK3β. Journal of Biological Chemistry, 283(51), 35337-35353. https://doi.org/10.1074/jbc.m803342200

Vascular endothelial growth factor (VEGF) is a vital angiogenic effector, regulating key angiogenic processes. Vascular development relies on numerous signaling pathways, of which those induced by transforming growth factor-β (TGFβ) are critical. The... Read More about Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor β1: REQUIREMENT FOR Smads,β-CATENIN, AND GSK3β.