All Outputs (9)

Version 3: Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom (2024)
Preprint / Working Paper
Hinds, J., Apaa, T., Parry, R. H., Withers, A. J., MacKenzie, L., Staley, C., Morrison, J., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W., Lambin, X., Loose, M., Mathews, F., Tarlinton, R., & Blanchard, A. (2024). Version 3: Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom

The Caliciviridae family, comprising positive-sense RNA viruses, is characterised by its non-enveloped, small virions, broad host range, and notable tendency for host switching. These viruses are primarily associated with gastroenteric disease, thoug... Read More about Version 3: Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom.

Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients (2023)
Preprint / Working Paper
Tarlinton, R., Tanescu, R., Shannon-Lowe, C., & Gran, B. (2023). Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients

Background Epstein Barr Virus (EBV) infection of B cells is now understood to be one of the triggering events for the development of Multiple Sclerosis (MS), a progressive immune-mediated disease of the central nervous system. EBV infection is also l... Read More about Ocrelizumab B cell depletion has no effect on HERV RNA expression in PBMC in MS patients.

COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS. (2023)
Preprint / Working Paper
Castillo-Aliaga, C., Blanchard, A. M., Castro-Seriche, S., Hidalgo-Hermoso, E., Jerez-Morales, A., Loose, M. W., & Tarlinton, R. E. (2023). COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS

Knowledge of Feline Leukemia Virus (FeLV) sequence variation has mainly been developed using Sanger sequencing methods. However, advances in next generation sequencing methods and their broad use in laboratories has been changing our understanding of... Read More about COMPARISON BETWEEN SANGER, ILLUMINA AND NANOPORE SEQUENCING EVIDENCING INTRA-HOST VARIATION OF FELINE LEUKEMIA VIRUS THAT INFECTS DOMESTIC CATS..

Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus (2023)
Preprint / Working Paper
Apaa, T., Withers, A. J., McKenzie, L., Staley, C., Blanchard, A., Bennett, M., Bremner-Harrison, S., Chadwick, E. A., Hailer, F., Harrison, S. W., Lambin, X., Loose, M., Mathews, F., & Tarlinton, R. (2023). Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus

Repeat spillover of SARS-CoV-2 into new hosts has highlighted the critical role of cross species transmission of coronaviruses and establishment of new reservoirs of virus in pandemic and epizootic spread of coronaviruses. Species particularly suscep... Read More about Lack of detection of SARS-CoV-2 in British wildlife 2020-21 and first description of a stoat (Mustela erminea) Minacovirus.

Version 4: Antiviral activity of salt-coated materials against SARS-CoV-2. (2023)
Preprint / Working Paper
Coleman, C. M., Wang, B., Wang, Y., Tapia-Brito, E., Chen, Z., Riffat, J., Riffat, S., Tarlinton, R., & Ghaemmaghami, A. Version 4: Antiviral activity of salt-coated materials against SARS-CoV-2

The SARS-CoV-2 pandemic demonstrated the importance of human coronaviruses and the need to develop materials to prevent the spread of emergent viruses. Here we describe that simple salt coating on a range of surfaces can degrade SARS-CoV-2.

Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21 (2023)
Preprint / Working Paper
Zachariah, A., Krishnankutty, S. P., Manazhi, J., Omanakuttan, V., Santosh, S., Blanchard, A. M., & Tarlinton, R. E. (2023). Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21

Spill over of SARs-CoV-2 into a variety of wild and domestic animals has been an ongoing feature of the human pandemic. The establishment of a new reservoir in white tailed deer in North America and increasing divergence of the viruses circulating in... Read More about Lack of detection of SARS-CoV-2 in Wildlife from Kerala, India in 2020-21.

UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI) (2023)
Preprint / Working Paper
McClaughlin, E., Elliott, S., Jewitt, S., Smallman-Raynor, M., Dunham, S., Parnell, T., Clark, M., & Tarlinton, R. UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI)

The scale of the current outbreak of highly pathogenic avian influenza (HPAI) due to the A/H5N1 virus in the United Kingdom is unprecedented. In addition to its economic impact on the commercial poultry sector, the disease has devastated wild bird co... Read More about UK Flockdown: Exploring the knowledge, attitudes and practices of backyard poultry keepers surrounding Highly Pathogenic Avian Influenza (HPAI).

Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution (2022)
Preprint / Working Paper
Tarlinton, R. E., Sarker, N., Fabijan, J., Dottorini, T., Woolford, L., Meers, J., Simmons, G., Owen, H., Seddon, J., Hemmatzedah, F., Trott, D., Speight, N., & Emes, R. (2022). Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution

Koala retrovirus (KoRV) is unique amongst endogenous (inherited) retroviruses in that its incorporation to the host genome is still active, providing an opportunity to study what drives this fundamental process in vertebrate genome evolution. Animals... Read More about Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution.

Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports its Classification as a Novel Species (2019)
Preprint / Working Paper
Chappell, J. G., Tsoleridis, T., Onianwa, O., Drake, G., Ashpole, I., Dobbs, P., Edema, W., Kumi-Ansah, F., Bennett, M., Tarlinton, R. E., Ball, J. K., & McClure, C. P. (2019). Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports its Classification as a Novel Species

Hantaviruses are a diverse group of single-stranded, negative-sensed RNA viruses, known to cause sporadic outbreaks of potentially fatal human disease. To date, only two Orthohantavirus species have been detected in the UK - Seoul virus and Tatenale.... Read More about Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports its Classification as a Novel Species.