Skip to main content

Research Repository

Advanced Search

All Outputs (65)

Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis (2019)
Journal Article
Rowbotham, N. J., Smith, S. J., Elliott, Z. C., Leighton, P. A., Rayner, O. C., Morley, R., & Smyth, A. R. (2019). Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis. Research Involvement and Engagement, 5(1), Article 24. https://doi.org/10.1186/s40900-019-0159-x

Background The James Lind Alliance (JLA) method is well recognised for setting research priorities. The JLA approach involves a combination of surveys and workshop interactions between patients, carers and health care professionals to identify and... Read More about Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis.

Seeking a practical definition of stable glaucoma: a Delphi consensus survey of UK glaucoma consultants (2019)
Journal Article
Lakhani, B. K., Giannouladis, K., Leighton, P., & King, A. J. (2019). Seeking a practical definition of stable glaucoma: a Delphi consensus survey of UK glaucoma consultants. Eye, https://doi.org/10.1038/s41433-019-0540-x

© 2019, The Author(s), under exclusive licence to The Royal College of Ophthalmologists. Background: To generate a practical and clinically useful consensus definition of ‘stable glaucoma’ to aid provision of glaucoma services in the UK and to provid... Read More about Seeking a practical definition of stable glaucoma: a Delphi consensus survey of UK glaucoma consultants.

Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials (2019)
Journal Article
Mousoulis, C., Thomas, K., Leighton, P., Deshmukh, S., Grindlay, D., & Karantana, A. (2020). Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials. Journal of Hand Surgery (European Volume), 45(2), 111-118. https://doi.org/10.1177/1753193419865897

The aim of this study was to identify and assess all existing randomized studies on treatment interventions for hand fractures and joint injuries, to inform practice and plan future research. PubMed, Cochrane CENTRAL, MEDLINE and Embase were searche... Read More about Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials.

Exploring patients' expectations and preferences of glaucoma surgery outcomes to facilitate healthcare delivery and inform future glaucoma research (2019)
Journal Article
King, A. J., Kulkarni, B. B., & Leighton, P. (2019). Exploring patients' expectations and preferences of glaucoma surgery outcomes to facilitate healthcare delivery and inform future glaucoma research. British Journal of Ophthalmology, bjophthalmol-2018-313401. https://doi.org/10.1136/bjophthalmol-2018-313401

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. Introduction: Glaucoma is a lifelong condition often requiring surgical intervention. To allow us to inform patients' expectations of surgery... Read More about Exploring patients' expectations and preferences of glaucoma surgery outcomes to facilitate healthcare delivery and inform future glaucoma research.

Defining displacement thresholds for surgical intervention for distal radius fractures – a Delphi study (2019)
Journal Article
Johnson, N., Leighton, P., Pailthorpe, C., Dias, J., & Distal Radius Fracture Delphi Study Group. (2019). Defining displacement thresholds for surgical intervention for distal radius fractures – a Delphi study. PLoS ONE, 14(1), 1-12. https://doi.org/10.1371/journal.pone.0210462

Distal radius fractures are very common yet controversy exists regarding which require treatment and is reflected by significant variation in surgical intervention rate. Evidence regarding which fractures would benefit from intervention is varied and... Read More about Defining displacement thresholds for surgical intervention for distal radius fractures – a Delphi study.

Chair based exercise in community settings: a cluster randomised feasibility study (2018)
Journal Article
Robinson, K., Long, A., Leighton, P., Armstrong, S., Pulikottill-Jacob, R., Gladman, J., …Masud, T. (2018). Chair based exercise in community settings: a cluster randomised feasibility study. BMC Geriatrics, 18(1), Article 82. https://doi.org/10.1186/s12877-018-0769-4

Background: Some older people who find standard exercise programmes too strenuous may be encouraged to exercise while remaining seated - chair based exercises (CBE). We previously developed a consensus CBE programme (CCBE) following a modified Delphi... Read More about Chair based exercise in community settings: a cluster randomised feasibility study.

Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach (2018)
Journal Article
Leighton, P., Brealey, S. D., & Dias, J. J. (in press). Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach. Journal of Evidence-Based Medicine, https://doi.org/10.1111/jebm.12271

Objective To explore stakeholder perspectives upon participant retention in clinical trials, and to generate strategies to support retention in a surgical, clinical trial. Study Design & Setting The SWIFFT trial is a multi-centre study com... Read More about Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach.

The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers (2017)
Journal Article
Rowbotham, N. J., Smith, S., Leighton, P., Rayner, O. C., Gathercole, K., Elliott, Z., …Smyth, A. R. (2018). The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers. Thorax, 73(4), 388-390. https://doi.org/10.1136/thoraxjnl-2017-210473

There remain many treatment uncertainties in cystic fibrosis (CF). With limited resources, research should focus on questions which are most important to the CF community. We conducted a James Lind Alliance Priority Setting Partnership in CF. Researc... Read More about The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and health care providers.

Feasibility of an online intervention (STAK-D) to promote physical activity in children with type 1 diabetes: protocol for a randomised controlled trial (2016)
Journal Article
Blake, H., Quirk, H., Leighton, P., Randell, T., Greening, J., Guo, B., & Glazebrook, C. (2016). Feasibility of an online intervention (STAK-D) to promote physical activity in children with type 1 diabetes: protocol for a randomised controlled trial. Trials, 17(283), https://doi.org/10.1186/s13063-016-1719-0

Background: Regular physical activity has important health benefits for children with type 1 diabetes mellitus (T1DM), yet children and their parents face barriers to participation such as lack of self-efficacy or concerns around hypoglycaemia. Multi... Read More about Feasibility of an online intervention (STAK-D) to promote physical activity in children with type 1 diabetes: protocol for a randomised controlled trial.

Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT) protocol: a pragmatic multi-centre randomised controlled trial of cast treatment versus surgical fixation for the treatment of bi-cortical, minimally displaced fractures of the scaphoid waist in adults (2016)
Journal Article
Dias, J., Brealey, S., Choudhary, S., Cook, L., Costa, M., Fairhurst, C., …Torgerson, D. (2016). Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT) protocol: a pragmatic multi-centre randomised controlled trial of cast treatment versus surgical fixation for the treatment of bi-cortical, minimally displaced fractures of the scaphoid waist in adults. BMC Musculoskeletal Disorders, 17(1), Article 248. https://doi.org/10.1186/s12891-016-1107-7

Background: A scaphoid fracture is the most common type of carpal fracture affecting young active people. The optimal management of this fracture is uncertain. When treated with a cast, 88 to 90 % of these fractures unite; however, for the remaining... Read More about Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT) protocol: a pragmatic multi-centre randomised controlled trial of cast treatment versus surgical fixation for the treatment of bi-cortical, minimally displaced fractures of the scaphoid waist in adults.

Home-administered pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): study protocol for a randomised controlled trial (2016)
Journal Article
das Nair, R., Anderson, P., Clarke, S. P., Leighton, P., Lincoln, N., Mhizha-Murira, J. R., …Walsh, D. A. (2016). Home-administered pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): study protocol for a randomised controlled trial. Trials, 17(54), 1-11. https://doi.org/10.1186/s13063-016-1165-z

Background: Knee replacement surgery reduces pain for many people with osteoarthritis (OA). However, surgical outcomes are partly dependent on patients’ moods, and those with depression or anxiety have worse outcomes. Approximately one-third of peopl... Read More about Home-administered pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): study protocol for a randomised controlled trial.

Prescribing opioid analgesics for chronic non-malignant pain in general practice - a survey of attitudes and practice (2015)
Journal Article
Blake, H., Leighton, P., van der Walt, G., & Ravenscroft, A. (2015). Prescribing opioid analgesics for chronic non-malignant pain in general practice - a survey of attitudes and practice. British Journal of Pain, 9(4), https://doi.org/10.1177/2049463715579284

Background: This study replicates a previous postal survey of general practitioners (GPs) to explore whether attitudes to opioid prescribing have changed at a time when the number of opioid prescriptions issued in primary care has increased. Metho... Read More about Prescribing opioid analgesics for chronic non-malignant pain in general practice - a survey of attitudes and practice.

Assessment of the feasibility and clinical value of further research to evaluate the management options for children with Down syndrome and otitis media (2014)
Journal Article

Background There is clinical uncertainty of the benefits and costs of different treatment options for children with Down syndrome who have glue ear. This study was designed to assess the extent of this lack of knowledge and determine if pursuing fur... Read More about Assessment of the feasibility and clinical value of further research to evaluate the management options for children with Down syndrome and otitis media.