Comparing different analysis methods for quantifying the MRI amide proton transfer (APT) effect in hyperacute stroke patients

Tee, Y. K.; Harston, G. W. J.; Blockley, N.; Okell, Thomas W.; Levman, J.; Sheerin, F.; Cellerini, M.; Jezzard, P.; Kennedy, J.; Payne, S. J.; Chappell, M. A.

doi:10.1002/nbm.3147

All Outputs (26)

Sources of systematic error in calibrated BOLD based mapping of baseline oxygen extraction fraction (2015)
Journal Article
Blockley, N. P., Griffeth, V. E., Stone, A. J., Hare, H. V., & Bulte, D. P. (2015). Sources of systematic error in calibrated BOLD based mapping of baseline oxygen extraction fraction. NeuroImage, 122, 105-113. https://doi.org/10.1016/j.neuroimage.2015.07.059

Hemispheric asymmetry in cerebrovascular reactivity of the human primary motor cortex: an in vivo study at 7 T (2015)
Journal Article
Driver, I. D., Andoh, J., Blockley, N. P., Francis, S. T., Gowland, P. A., & Paus, T. (2015). Hemispheric asymmetry in cerebrovascular reactivity of the human primary motor cortex: an in vivo study at 7 T. NMR in Biomedicine, 28(5), 538-545. https://doi.org/10.1002/nbm.3282

Current functional MRI (fMRI) approaches assess underlying neuronal activity through monitoring the related local variations in cerebral blood oxygenation, blood volume and blood flow. This vascular response is likely to vary across brain regions and... Read More about Hemispheric asymmetry in cerebrovascular reactivity of the human primary motor cortex: an in vivo study at 7 T.

Investigating the field-dependence of the Davis model: Calibrated fMRI at 1.5, 3 and 7 T (2015)
Journal Article
Hare, H. V., Blockley, N. P., Gardener, A. G., Clare, S., & Bulte, D. P. (2015). Investigating the field-dependence of the Davis model: Calibrated fMRI at 1.5, 3 and 7 T. NeuroImage, 112, 189-196. https://doi.org/10.1016/j.neuroimage.2015.02.068

Gas calibrated fMRI in its most common form uses hypercapnia in conjunction with the Davis model to quantify relative changes in the cerebral rate of oxygen consumption (CMRO2) in response to a functional stimulus. It is most commonly carried out at... Read More about Investigating the field-dependence of the Davis model: Calibrated fMRI at 1.5, 3 and 7 T.

Identifying the ischaemic penumbra using pH-weighted magnetic resonance imaging (2014)
Journal Article
Harston, G. W. J., Tee, Y. K., Blockley, N., Okell, T. W., Thandeswaran, S., Shaya, G., Sheerin, F., Cellerini, M., Payne, S., Jezzard, P., Chappell, M., & Kennedy, J. (2015). Identifying the ischaemic penumbra using pH-weighted magnetic resonance imaging. Brain, 138(1), 36-42. https://doi.org/10.1093/brain/awu374

© 2014 The Author. The original concept of the ischaemic penumbra suggested imaging of regional cerebral blood flow and metabolism would be required to identify tissue that may benefit from intervention. Amide proton transfer magnetic resonance imagi... Read More about Identifying the ischaemic penumbra using pH-weighted magnetic resonance imaging.

Calibrating the BOLD response without administering gases: comparison of hypercapnia calibration with calibration using an asymmetric spin echo (2014)
Journal Article
Blockley, N. P., Griffeth, V. E., Simon, A. B., Dubowitz, D. J., & Buxton, R. B. (2015). Calibrating the BOLD response without administering gases: comparison of hypercapnia calibration with calibration using an asymmetric spin echo. NeuroImage, 104, 423-429. https://doi.org/10.1016/j.neuroimage.2014.09.061

Comparing different analysis methods for quantifying the MRI amide proton transfer (APT) effect in hyperacute stroke patients (2014)
Journal Article
Tee, Y. K., Harston, G. W. J., Blockley, N., Okell, T. W., Levman, J., Sheerin, F., Cellerini, M., Jezzard, P., Kennedy, J., Payne, S. J., & Chappell, M. A. (2014). Comparing different analysis methods for quantifying the MRI amide proton transfer (APT) effect in hyperacute stroke patients. NMR in Biomedicine, 27(9), 1019-1029. https://doi.org/10.1002/nbm.3147

Amide proton transfer (APT) imaging is a pH mapping method based on the chemical exchange saturation transfer phenomenon that has potential for penumbra identification following stroke. The majority of the literature thus far has focused on generatin... Read More about Comparing different analysis methods for quantifying the MRI amide proton transfer (APT) effect in hyperacute stroke patients.