All Outputs (6)

New colours for old in the blue-cheese fungus Penicillium roqueforti (2024)
Journal Article
Cleere, M. M., Novodvorska, M., Geib, E., Whittaker, J., Dalton, H., Salih, N., Hewitt, S., Kokolski, M., Brock, M., & Dyer, P. S. (2024). New colours for old in the blue-cheese fungus Penicillium roqueforti. npj Science of Food, 8(1), Article 3. https://doi.org/10.1038/s41538-023-00244-9

Penicillium roqueforti is used worldwide in the production of blue-veined cheese. The blue-green colour derives from pigmented spores formed by fungal growth. Using a combination of bioinformatics, targeted gene deletions, and heterologous gene expre... Read More about New colours for old in the blue-cheese fungus Penicillium roqueforti.

Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose (2020)
Journal Article
van Munster, J. M., Daly, P., Blythe, M. J., Ibbett, R., Kokolski, M., Gaddipati, S., Lindquist, E., Singan, V. R., Barry, K. W., Lipzen, A., Ngan, C. Y., Petzold, C. J., Chan, L. J. G., Arvas, M., Raulo, R., Pullan, S. T., Delmas, S., Grigoriev, I. V., Tucker, G. A., Simmons, B. A., & Archer, D. B. (2020). Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose. Biotechnology for Biofuels, 13(1), Article 69. https://doi.org/10.1186/s13068-020-01702-2

Background
Understanding how fungi degrade lignocellulose is a cornerstone of improving renewables-based biotechnology, in particular for the production of hydrolytic enzymes. Considerable progress has been made in investigating fungal degradation d... Read More about Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose.

Transcriptomic responses of mixed cultures of ascomycete fungi to lignocellulose using dual RNA-seq reveal inter-species antagonism and limited beneficial effects on CAZyme expression (2017)
Journal Article
Daly, P., van Munster, J. M., Kokolski, M., Sang, F., Blythe, M. J., Malla, S., Velasco de Castro Oliveira, J., Goldman, G. H., & Archer, D. B. (2017). Transcriptomic responses of mixed cultures of ascomycete fungi to lignocellulose using dual RNA-seq reveal inter-species antagonism and limited beneficial effects on CAZyme expression. Fungal Genetics and Biology, 102, https://doi.org/10.1016/j.fgb.2016.04.005

Gaining new knowledge through fungal monoculture responses to lignocellulose is a widely used approach that can lead to better cocktails for lignocellulose saccharification (the enzymatic release of sugars which are subsequently used to make biofuels... Read More about Transcriptomic responses of mixed cultures of ascomycete fungi to lignocellulose using dual RNA-seq reveal inter-species antagonism and limited beneficial effects on CAZyme expression.

Expression of Aspergillus niger CAZymes is determined by compositional changes in wheat straw generated by hydrothermal or ionic liquid pretreatments (2017)
Journal Article
Daly, P., van Munster, J. M., Blythe, M. J., Ibbett, R., Kokolski, M., Gaddipati, S., Lindquist, E., Singan, V. R., Barry, K. W., Lipzen, A., Ngan, C. Y., Petzold, C. J., Chan, L. J. G., Pullan, S. T., Delmas, S., Waldron, P. R., Grigoriev, I. V., Tucker, G. A., Simmons, B. A., & Archer, D. B. (2017). Expression of Aspergillus niger CAZymes is determined by compositional changes in wheat straw generated by hydrothermal or ionic liquid pretreatments. Biotechnology for Biofuels, 10(1), Article 35. https://doi.org/10.1186/s13068-017-0700-9

Background

The capacity of fungi, such as Aspergillus niger, to degrade lignocellulose is harnessed in biotechnology to generate biofuels and high-value compounds from renewable feedstocks. Most feedstocks are currently pretreated to increase enzy... Read More about Expression of Aspergillus niger CAZymes is determined by compositional changes in wheat straw generated by hydrothermal or ionic liquid pretreatments.

The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger (2016)
Journal Article
Raulo, R., Archer, D. B., & Kokolski, M. (2016). The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger. AMB Express, 6(5), https://doi.org/10.1186/s13568-016-0177-0

Genes encoding the key transcription factors (TF) XlnR, ClrA and ClrB were deleted from Aspergillus niger and the resulting strains were assessed for growth on glucose and wheat straw, transcription of genes encoding glycosyl hydrolases and saccharif... Read More about The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger.

Uncovering the genome-wide transcriptional responses of the filamentous fungus Aspergillus niger to lignocellulose using RNA sequencing (2012)
Journal Article
Delmas, S., Pullan, S. T., Gaddipati, S., Kokolski, M., Malla, S., Blythe, M. J., Ibbett, R., Campbell, M., Liddell, S., Aboobaker, A., Tucker, G. A., & Archer, D. B. (2012). Uncovering the genome-wide transcriptional responses of the filamentous fungus Aspergillus niger to lignocellulose using RNA sequencing. PLoS Genetics, 8(8), Article e1002875. https://doi.org/10.1371/journal.pgen.1002875

A key challenge in the production of second generation biofuels is the conversion of lignocellulosic substrates into fermentable sugars. Enzymes, particularly those from fungi, are a central part of this process, and many have been isolated and chara... Read More about Uncovering the genome-wide transcriptional responses of the filamentous fungus Aspergillus niger to lignocellulose using RNA sequencing.