Study Protocol: The Heart and Brain Study

Suri, Sana; Bulte, Daniel; Chiesa, Scott T.; Ebmeier, Klaus P.; Jezzard, Peter; Rieger, Sebastian W.; Pitt, Jemma E.; Griffanti, Ludovica; Okell, Thomas W.; Craig, Martin; Chappell, Michael A.; Blockley, Nicholas P.; Kivim�ki, Mika; Singh-Manoux, Archana; Khir, Ashraf W.; Hughes, Alun D.; Deanfield, John E.; Jensen, Daria E. A.; Green, Sebastian F.; Sigutova, Veronika; Jansen, Michelle G.; Zsoldos, Enik?; Mackay, Clare E.

doi:10.3389/fphys.2021.643725

All Outputs (2)

Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model (2021)
Journal Article
Plas, M. C. E., Craig, M., Schmid, S., Chappell, M. A., & Osch, M. J. P. (2022). Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model. Magnetic Resonance in Medicine, 87(1), 85-101. https://doi.org/10.1002/mrm.28960

Purpose
In this paper, the ability to quantify cerebral blood flow by arterial spin labeling (ASL) was studied by investigating the separation of the macrovascular and tissue component using a 2-component model. Underlying assumptions of this model,... Read More about Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model.

Study Protocol: The Heart and Brain Study (2021)
Journal Article
Suri, S., Bulte, D., Chiesa, S. T., Ebmeier, K. P., Jezzard, P., Rieger, S. W., …Mackay, C. E. (2021). Study Protocol: The Heart and Brain Study. Frontiers in Physiology, 12, Article 643725. https://doi.org/10.3389/fphys.2021.643725

Background: It is well-established that what is good for the heart is good for the brain. Vascular factors such as hypertension, diabetes, and high cholesterol, and genetic factors such as the apolipoprotein E4 allele increase the risk of developing... Read More about Study Protocol: The Heart and Brain Study.