Introduction to the Special Section on Computational Modeling and Digital Twin Technology in Biomedical Engineering
(2024)
Journal Article
Laviola, M. (2024). Introduction to the Special Section on Computational Modeling and Digital Twin Technology in Biomedical Engineering. IEEE Open Journal of Engineering in Medicine and Biology, 5, 607-610. https://doi.org/10.1109/ojemb.2024.3428898
All Outputs (5)
Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive Ventilation (2024)
Journal Article
Weaver, L., Shamohammadi, H., Saffaran, S., Tonelli, R., Laviola, M., Laffey, J. G., Camporota, L., Scott, T. E., Hardman, J. G., Clini, E., & Bates, D. G. (2024). Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive Ventilation. Critical Care Medicine, 52(9), e473-e484. https://doi.org/10.1097/CCM.0000000000006337Objectives: To clarify the mechanistic basis for the success or failure of noninvasive ventilation (NIV) in acute hypoxemic respiratory failure (AHRF). Design: We created digital twins based on mechanistic computational models of individual patients... Read More about Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive Ventilation.
Evaluating current guidelines for cardiopulmonary resuscitation using an integrated computational model of the cardiopulmonary system (2023)
Journal Article
Daudre-Vignier, C., Bates, D. G., Scott, T. E., Hardman, J. G., & Laviola, M. (2023). Evaluating current guidelines for cardiopulmonary resuscitation using an integrated computational model of the cardiopulmonary system. Resuscitation, 186, Article 109758. https://doi.org/10.1016/j.resuscitation.2023.109758Objective: We aimed to use a high-fidelity computational model that captures key interactions between the cardiovascular and pulmonary systems to investigate whether current CPR protocols could potentially be improved. Methods: We developed and valid... Read More about Evaluating current guidelines for cardiopulmonary resuscitation using an integrated computational model of the cardiopulmonary system.
Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study. Response to Br J Anaesth 2022; 129: 581–7 (2023)
Journal Article
Ellis, R., Laviola, M., Stolady, D., Valentine, R. L., Pillai, A., & Hardman, J. G. (2023). Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study. Response to Br J Anaesth 2022; 129: 581–7. British Journal of Anaesthesia, 130(4), e429-e430. https://doi.org/10.1016/j.bja.2023.01.007
Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study (2022)
Journal Article
Ellis, R., Laviola, M., Stolady, D., Valentine, R. L., Pillai, A., & Hardman, J. G. (2022). Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study. British Journal of Anaesthesia, 129(4), 581-587. https://doi.org/10.1016/j.bja.2022.06.021Background: Hypoxaemia during general anaesthesia can cause harm. Apnoeic oxygenation extends safe apnoea time, reducing risk during airway management. We hypothesised that low-flow nasal oxygenation (LFNO) would extend safe apnoea time similarly to... Read More about Comparison of apnoeic oxygen techniques in term pregnant subjects: a computational modelling study.