All Outputs (2)

Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis (2025)
Journal Article
Allen, C. M., Clarke, M. A., Pai, H. V., Cauchi, M., Hawken, J., Htet, Z. M., Allen-Philbey, K., Mohamed, B., Fitzsimmons, D., Das Nair, R., Morgan, P., Partlett, C., Dineen, R. A., Schmierer, K., Tallantyre, E. C., & Evangelou, N. (2025). Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis. Neurology Open Access, 1(2), Article e000017. https://doi.org/10.1212/WN9.0000000000000017

Background and Objectives
The central vein sign (CVS) describes the presence of venules within multiple sclerosis (MS) brain lesions, visible on T2*-weighted MRI. In the upcoming revision of the MS diagnostic criteria, the simplified “rule of 6” (i.... Read More about Comparison of the Diagnostic Performance of the Central Vein Sign and CSF Oligoclonal Bands Supporting the Diagnosis of Multiple Sclerosis.

T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI (2025)
Journal Article
Marshall, M., Aphiwatthanasumet, K., Mougin, O., Stadelmann, C., Morgan, P. S., Dineen, R. A., Gowland, P., Evangelou, N., & Clarke, M. A. (2025). T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI. Journal of Neuroimaging, 35(3), Article e70044. https://doi.org/10.1111/jon.70044

Background and Purpose:
Chronic active multiple sclerosis (MS) lesions represent a particularly destructive subset of lesions on pathology. However, their imaging correlates, including paramagnetic rim lesions (PRLs) detected on susceptibility-weig... Read More about T₁-Dark Rim as a Marker of New and Chronic Active Multiple Sclerosis Lesions: A Serial Study With Frequent 7T MRI.