All Outputs (10)

Quantification of differences in germination behaviour of pelleted and coated sugar beet seeds using X-ray Computed Tomography (X-ray CT) (2017)
Journal Article
Blunk, S., Malik, A. H., de Heer, M. I., Ekblad, T., Fredlund, K., Mooney, S. J., & Sturrock, C. J. (in press). Quantification of differences in germination behaviour of pelleted and coated sugar beet seeds using X-ray Computed Tomography (X-ray CT). Biomedical Physics and Engineering Express, 3(4), https://doi.org/10.1088/2057-1976/aa7c3f

Seed enhancement technologies i.e. priming, pelleting and coating have been extensively9 used throughout the last century to improve crop yield and to reduce losses associated with pest infestation. However, until recently, it has not been possible t... Read More about Quantification of differences in germination behaviour of pelleted and coated sugar beet seeds using X-ray Computed Tomography (X-ray CT).

Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise (2014)
Journal Article
Williams, S., Horner, J., Orton, E., Green, M. J., McMullen, S., Mobasheri, A., & Freeman, S. (2014). Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise. Equine Veterinary Journal, 47(1), https://doi.org/10.1111/evj.12238

Reasons for performing study: A change in management from pasture to stabling is a risk factor for equine colic.

Objectives: To investigate the effect of a management change from pasture with no controlled exercise to stabling with light exercise... Read More about Water intake, faecal output and intestinal motility in horses moved from pasture to a stabled management regime with controlled exercise.

Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β (2013)
Journal Article
Williams, A., Smith, J. R., Allaway, D., Harris, P., Liddell, S., & Mobasheri, A. (2013). Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β. Arthritis Research and Therapy, 15(6), Article R223. https://doi.org/10.1186/ar4424

Introduction: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly... Read More about Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β.

Application of machine learning to proteomics data: classification and biomarker identification in postgenomics biology (2013)
Journal Article
Swan, A. L., Mobasheri, A., Allaway, D., Liddell, S., & Bacardit, J. (2013). Application of machine learning to proteomics data: classification and biomarker identification in postgenomics biology. OMICS, 17(12), https://doi.org/10.1089/omi.2013.0017

Mass spectrometry is an analytical technique for the characterization of biological samples and is increasingly used in omics studies because of its targeted, nontargeted, and high throughput abilities. However, due to the large datasets generated, i... Read More about Application of machine learning to proteomics data: classification and biomarker identification in postgenomics biology.

Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study (2013)
Journal Article
Manouchehrinia, A., Tench, C. R., Maxted, J., Bibani, R. H., Britton, J., & Constantinescu, C. S. (2013). Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study. Brain, 136(7), https://doi.org/10.1093/brain/awt139

Tobacco smoking has been linked to an increased risk of multiple sclerosis. However, to date, results from the few studies on the impact of smoking on the progression of disability are conflicting. The aim of this study was to investigate the effects... Read More about Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study.

Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning (2013)
Journal Article
Swan, A. L., Hillier, K. L., Smith, J. R., Allaway, D., Liddell, S., Bacardit, J., & Mobasheri, A. (2013). Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning. BMC Musculoskeletal Disorders, 14, Article 349. https://doi.org/10.1186/1471-2474-14-349

Background: Osteoarthritis (OA) is an inflammatory disease of synovial joints involving the loss and degeneration of articular cartilage. The gold standard for evaluating cartilage loss in OA is the measurement of joint space width on standard radiog... Read More about Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning.

Curcumin modulates nuclear factor kB (NF-KB)-mediated inflammation in human tenocytes in vitro: Role of the PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY (2011)
Journal Article
Buhrmann, C., Mobasheri, A., Busch, F., Aldinger, C., Stahlmann, R., Montaseri, A., & Shakibaei, M. (2011). Curcumin modulates nuclear factor kB (NF-KB)-mediated inflammation in human tenocytes in vitro: Role of the PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY. Journal of Biological Chemistry, 286(32), https://doi.org/10.1074/jbc.M111.256180

Inflammatory processes play essential roles in the pathogenesis of tendinitis and tendinopathy. These events are accompanied by catabolic processes initiated by pro-inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TN... Read More about Curcumin modulates nuclear factor kB (NF-KB)-mediated inflammation in human tenocytes in vitro: Role of the PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY.

From multipotent cells to fully differentiated connective tissue cells for regenerative medicine: emerging applications of mesenchymal stem cells (2011)
Book Chapter
Mobasheri, A., Richardson, S. M., Hoyland, J. A., Buhrmann, C., & Shakibaei, M. (2011). From multipotent cells to fully differentiated connective tissue cells for regenerative medicine: emerging applications of mesenchymal stem cells. In D. Eberli (Ed.), Regenerative medicine and tissue engineering: cells and biomaterials. InTech. https://doi.org/10.5772/837

High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation (2011)
Journal Article
Clutterbuck, A. L., Smith, J. R., Allaway, D., Harris, P., Liddell, S., & Mobasheri, A. (2011). High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation. Journal of Proteomics, 74(5), https://doi.org/10.1016/j.jprot.2011.02.017

This study employed a targeted high-throughput proteomic approach to identify the major proteins present in the secretome of articular cartilage. Explants from equine metacarpophalangeal joints were incubated alone or with interleukin-1beta (IL-1β, 1... Read More about High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation.

The Virtual International Stroke Trials Archive (2007)
Journal Article
Myzoon, A., Bath, P. M., Curram, J., Davis, S. M., Diener, H.-C., Donnan, G. A., Fisher, M., Gregson, B. A., Grotta, J., Hacke, W., Hennerici, M. G., Hommel, M., Kaste, M., Marler, J. R., Sacco, R. L., Teal, P., Wahlgren, N.-G., Warach, S., Weir, C. J., & Lees, K. R. (2007). The Virtual International Stroke Trials Archive. Stroke, 38(6),

Background and Purpose - Stroke has global importance and it causes an increasing amount of human suffering and
economic burden, but its management is far from optimal. The unsuccessful outcome of several research programs
highlights the need for r... Read More about The Virtual International Stroke Trials Archive.