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Using Object-Oriented Simulation to Assess the Impact of the Frequency and Accuracy of Mobility Scoring on the Estimation of Epidemiological Parameters for Lameness in Dairy Herds (2024)
Journal Article
Clifton, R., Hyde, R., Can, E., Barden, M., Manning, A., Bradley, A., …O’Grady, L. (2024). Using Object-Oriented Simulation to Assess the Impact of the Frequency and Accuracy of Mobility Scoring on the Estimation of Epidemiological Parameters for Lameness in Dairy Herds. Animals, 14(12), 1760. https://doi.org/10.3390/ani14121760

Mobility scoring data can be used to estimate the prevalence, incidence, and duration of lameness in dairy herds. Mobility scoring is often performed infrequently with variable sensitivity, but how this impacts the estimation of lameness parameters i... Read More about Using Object-Oriented Simulation to Assess the Impact of the Frequency and Accuracy of Mobility Scoring on the Estimation of Epidemiological Parameters for Lameness in Dairy Herds.

Predictive modelling of deviation from expected milk yield in transition cows on automatic milking systems (2024)
Journal Article
Hannon, F. P., Green, M. J., O’Grady, L., Hudson, C., Gouw, A., & Randall, L. V. (2024). Predictive modelling of deviation from expected milk yield in transition cows on automatic milking systems. Preventive Veterinary Medicine, 225, Article 106160. https://doi.org/10.1016/j.prevetmed.2024.106160

The transition period is a pivotal time in the production cycle of the dairy cow. It is estimated that between 30% and 50% of all cows experience metabolic or infectious disease during this time. One of the most common and economically consequential... Read More about Predictive modelling of deviation from expected milk yield in transition cows on automatic milking systems.

Quantification of the effect of in utero events on lifetime resilience in dairy cows (2024)
Journal Article
Lewis, K., Shewbridge Carter, L., Bradley, A., Dewhurst, R., Forde, N., Hyde, R., …Green, M. (2024). Quantification of the effect of in utero events on lifetime resilience in dairy cows. Journal of Dairy Science, 107(7), 4616-4633. https://doi.org/10.3168/jds.2023-24215

Currently, the dairy industry is facing many challenges that could affect its sustainability, including climate change and public perception of the industry. As a result, interest is increasing in the concept of identifying resilient animals, those w... Read More about Quantification of the effect of in utero events on lifetime resilience in dairy cows.

An observational study of ear-tagged calf mortality (1 to 100 days) on Irish dairy farms and associations between biosecurity practices and calf mortality on farms participating in a Johne's disease control program (2023)
Journal Article
McAloon, C. G., Tratalos, J. A., O'Grady, L., Green, M. J., Gavey, L., Graham, D., …Mee, J. F. (2023). An observational study of ear-tagged calf mortality (1 to 100 days) on Irish dairy farms and associations between biosecurity practices and calf mortality on farms participating in a Johne's disease control program. Journal of Dairy Science, 106(7), 4966-4977. https://doi.org/10.3168/jds.2022-22519

Postnatal mortality among replacement stock has a detrimental effect on the social, economic, and environmental sustainability of dairy production. Calf mortality rates vary between countries and show differences in temporal trends; most, however, ar... Read More about An observational study of ear-tagged calf mortality (1 to 100 days) on Irish dairy farms and associations between biosecurity practices and calf mortality on farms participating in a Johne's disease control program.

Stability selection for mixed effect models with large numbers of predictor variables: A simulation study (2022)
Journal Article
Hyde, R., O'Grady, L., & Green, M. (2022). Stability selection for mixed effect models with large numbers of predictor variables: A simulation study. Preventive Veterinary Medicine, 206, Article 105714. https://doi.org/10.1016/j.prevetmed.2022.105714

Covariate selection when the number of available variables is large relative to the number of observations is problematic in epidemiology and remains the focus of continued research. Whilst a variety of statistical methods have been developed to atte... Read More about Stability selection for mixed effect models with large numbers of predictor variables: A simulation study.

Estimation of the serial interval and proportion of pre-symptomatic transmission events of COVID− 19 in Ireland using contact tracing data (2021)
Journal Article
McAloon, C. G., Wall, P., Griffin, J., Casey, M., Barber, A., Codd, M., …More, S. J. (2021). Estimation of the serial interval and proportion of pre-symptomatic transmission events of COVID− 19 in Ireland using contact tracing data. BMC Public Health, 21, Article 805. https://doi.org/10.1186/s12889-021-10868-9

Background

The serial interval is the period of time between the onset of symptoms in an infector and an infectee and is an important parameter which can impact on the estimation of the reproduction number. Whilst several parameters influencing in... Read More about Estimation of the serial interval and proportion of pre-symptomatic transmission events of COVID− 19 in Ireland using contact tracing data.

Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research (2020)
Journal Article
McAloon, C., Collins, Á., Hunt, K., Barber, A., Byrne, A. W., Butler, F., …More, S. J. (2020). Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research. BMJ Open, 10(8), Article e039652. https://doi.org/10.1136/bmjopen-2020-039652

Objectives: The aim of this study was to conduct a rapid systematic review and meta-analysis of estimates of the incubation period of COVID-19.

Design: Rapid systematic review and meta-analysis of observational research.

Setting: International... Read More about Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research.

Individual and herd-level milk ELISA test status for Johne's disease in Ireland after correcting for non-disease-associated variables (2020)
Journal Article
McAloon, C. G., O'Grady, L., Botaro, B., More, S. J., Doherty, M., Whyte, P., …Green, M. (2020). Individual and herd-level milk ELISA test status for Johne's disease in Ireland after correcting for non-disease-associated variables. Journal of Dairy Science, 103(10), 9345-9354. https://doi.org/10.3168/jds.2019-18018

Antibody-detecting tests for Mycobacterium avium ssp. paratuberculosis (MAP) have low sensitivity and imperfect specificity for detection of infection. Sensitivity increases as the disease progresses. Aside from infection status and stage of disease,... Read More about Individual and herd-level milk ELISA test status for Johne's disease in Ireland after correcting for non-disease-associated variables.

Low accuracy of Bayesian latent class analysis for estimation of herd-level true prevalence under certain disease characteristics—An analysis using simulated data (2018)
Journal Article
McAloon, C. G., Doherty, M. L., Whyte, P., Verdugo, C., Toft, N., More, S. J., …Green, M. J. (2019). Low accuracy of Bayesian latent class analysis for estimation of herd-level true prevalence under certain disease characteristics—An analysis using simulated data. Preventive Veterinary Medicine, 162, 117-125. https://doi.org/10.1016/j.prevetmed.2018.11.014

Estimation of the true prevalence of infected individuals involves the application of a diagnostic test to a population and adjusting according to test performance, sensitivity and specificity. Bayesian latent class analysis for the estimation of her... Read More about Low accuracy of Bayesian latent class analysis for estimation of herd-level true prevalence under certain disease characteristics—An analysis using simulated data.

Relative importance of herd-level risk factors for probability of infection with paratuberculosis in Irish dairy herds (2017)
Journal Article
McAloon, C. G., Doherty, M. L., Whyte, P., More, S. J., O'Grady, L., Citer, L., & Green, M. J. (2017). Relative importance of herd-level risk factors for probability of infection with paratuberculosis in Irish dairy herds. Journal of Dairy Science, 100(11), 9245-9257. https://doi.org/10.3168/jds.2017-12985

Control of paratuberculosis is challenging due to the relatively poor performance of diagnostic tests, a prolonged incubation period, and protracted environmental survival. Prioritization of herd-level interventions is not possible because putative r... Read More about Relative importance of herd-level risk factors for probability of infection with paratuberculosis in Irish dairy herds.

Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves (2016)
Journal Article
McAloon, C. G., Whyte, P., O'Grady, L., Lorenz, I., Green, M. J., Hogan, I., …Doherty, M. L. (2016). Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves. Veterinary Record, 179(2), Article 47. https://doi.org/10.1136/vr.103547

The objective of this cohort study was to assess the relationship between perinatal calf management practices relevant to the control of paratuberculosis and passive transfer of immunoglobulin in calves born in an endemically infected Irish dairy her... Read More about Relationship between selected perinatal paratuberculosis management interventions and passive transfer of immunity in dairy calves.

The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds (2015)
Journal Article
Somers, J. R., Huxley, J., Lorenz, I., Doherty, M. L., & O'Grady, L. (2015). The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds. Irish Veterinary Journal, 68, Article 14. https://doi.org/10.1186/s13620-015-0043-4

Background: The effects of lameness on fertility have been documented frequently but few data are available from seasonally breeding, pasture-based herds (such as those used in Ireland) where cows are housed during the winter months but managed at pa... Read More about The effect of Lameness before and during the breeding season on fertility in 10 pasture-based Irish dairy herds.