All Outputs (13)

Feasibility of delivering a randomized controlled trial of weighted blanket intervention to help agitation and disturbed sleep after brain injury (2024)
Journal Article

Sleep disturbance and agitation are common after acquired brain injury (ABI). Weighted blankets may help these symptoms in other conditions, but have not been trialed in ABI. We aimed to determine acceptability and feasibility of weighted blankets to... Read More about Feasibility of delivering a randomized controlled trial of weighted blanket intervention to help agitation and disturbed sleep after brain injury.

Management of acute cervical spinal cord injury in the non‐specialist intensive care unit: a narrative review of current evidence (2023)
Journal Article

Each year approximately one million people suffer spinal cord injury, which has significant physical, psychosocial and economic impacts on patients and their families. Spinal cord rehabilitation centres are a well-established part of the care pathway... Read More about Management of acute cervical spinal cord injury in the non‐specialist intensive care unit: a narrative review of current evidence.

Home-based virtual reality for help with symptoms of multiple sclerosis (2022)
Dataset

Childhood pet ownership and multiple sclerosis: A systematic review and meta-analysis (2021)
Journal Article

Background Many studies have been conducted investigating a range of environmental factors which have been implicated in the pathogenesis of multiple sclerosis (MS). We collated available data about exposure to domestic animals before symptom onse... Read More about Childhood pet ownership and multiple sclerosis: A systematic review and meta-analysis.

PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis (2020)
Journal Article

© 2020 Elsevier GmbH IL-23 is a potent stimulus for Th17 cells. These cells have a distinct developmental pathway from Th1 cells induced by IL-12 and are implicated in autoimmune and inflammatory disorders including multiple sclerosis (MS). TGF-β, IL... Read More about PAF-R on activated T cells: Role in the IL-23/Th17 pathway and relevance to multiple sclerosis.

Human animal interaction, animal assisted therapy and pet ownership in neurorehabilitation (2020)
Journal Article

Human animal interactions (HAI), animal assisted therapy (AAT) and pet ownership can confer huge benefits for patients undergoing neurorehabilitation, in inpatient and outpatient settings. However, these must be weighed against potential risks and di... Read More about Human animal interaction, animal assisted therapy and pet ownership in neurorehabilitation.

Prevalence of unmet needs for spasticity management in care home residents in the East Midlands, United Kingdom: a cross-sectional observational study (2019)
Journal Article

MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium (2017)
Journal Article

Leukocyte adhesion to brain endothelial cells, the blood-brain barrier main component, is a critical step in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS). Leukocyte adhesion is mediated mainly by selectins, cell adhe... Read More about MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium.

Adequacy of Online Patient Information Resources on Gout and Potentially Curative Urate-Lowering Treatment (2016)
Journal Article

© 2016, American College of Rheumatology Objective: To assess the content and readability of online patient information resources against the current understanding of gout. Methods: An online survey was undertaken using Google UK, USA, Australia, and... Read More about Adequacy of Online Patient Information Resources on Gout and Potentially Curative Urate-Lowering Treatment.

Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis (2015)
Journal Article

Clostridium difficile is an anaerobic, Gram-positive, and spore-forming bacterium that is the leading worldwide infective cause of hospital-acquired and antibiotic-associated diarrhea. Several studies have reported associations between humoral immuni... Read More about Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis.

Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study (2015)
Journal Article

Objective: To determine if comorbid asthma is associated with accumulation of multiple sclerosis (MS)-related impairment and disability. Method: We sent a comprehensive questionnaire to a cohort of patients with MS and examined the association bet... Read More about Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study.

Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells (2015)
Journal Article

© 2015 The Authors. Aims: To investigate the regulation of cannabinoid receptors CB1 and CB2 on immune cells by pro-inflammatory cytokines and its potential relevance to the inflammatory neurological disease, multiple sclerosis (MS). CB1 and CB2 sign... Read More about Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells.

Multiple sclerosis findings in the spinal cord (2007)
Journal Article