CpG methylation directly inhibits binding of the human papillomavirus type-16 E2 protein to specific DNA sequences
(1996)
Journal Article
Thain, A., Jenkins, O., Clarke, A. R., & Gaston, K. (1996). CpG methylation directly inhibits binding of the human papillomavirus type-16 E2 protein to specific DNA sequences. Journal of Virology, 70(10), 7233-7235. https://doi.org/10.1128/jvi.70.10.7233-7235.1996
CpG methylation of the human papillomavirus upstream regulatory region has previously been shown to reduce virus promoter activity. Here, we demonstrate that methylation of the CpG dinucleotides contained within the binding site of the human papillom... Read More about CpG methylation directly inhibits binding of the human papillomavirus type-16 E2 protein to specific DNA sequences.