All Outputs (2)

Novel haemodynamic structures in the human glomerulus (2018)
Journal Article
Neal, C., Arkill, K., Bell, J., Betteridge, K., Bates, D., Winlove, C., Salmon, A., & Harper, S. (in press). Novel haemodynamic structures in the human glomerulus. AJP - Renal Physiology, https://doi.org/10.1152/ajprenal.00566.2017

To investigate human glomerular structure under conditions of physiological perfusion we have analysed fresh and perfusion fixed normal human glomeruli at physiological hydrostatic and oncotic pressures using serial resin section reconstruction, conf... Read More about Novel haemodynamic structures in the human glomerulus.

Acute depletion of diacylglycerol from the Cis-Golgi affects localised nuclear envelope morphology during mitosis (2018)
Journal Article
Chung, G. H. C., Domart, M.-C., Peddie, C., Mantell, J., Mclaverty, K., Arabiotorre, A., Hodgson, L., Byrne, R. D., Verkade, P., Arkill, K. P., Collinson, L. M., & Larijani, B. (2018). Acute depletion of diacylglycerol from the Cis-Golgi affects localised nuclear envelope morphology during mitosis. Journal of Lipid Research, 59, 1402-1413. https://doi.org/10.1194/jlr.M083899

Dysregulation of nuclear envelope (NE) assembly results in various cancers; for example, renal and some lung carcinomas ensue due to NE malformation. The NE is a dynamic membrane compartment and its completion during mitosis, is a highly regulated pr... Read More about Acute depletion of diacylglycerol from the Cis-Golgi affects localised nuclear envelope morphology during mitosis.