Skip to main content

Research Repository

Advanced Search

All Outputs (96)

Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta-analysis (2015)
Journal Article
Aoyagi, Y., Beck, C. R., Dingwall, R., & Nguyen-Van-Tam, J. (2015). Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta-analysis. Influenza and Other Respiratory Viruses, 9(3), 120-130. https://doi.org/10.1111/irv.12310

To estimate the proportion of healthcare workers (HCWs) willing to work during an influenza pandemic and identify associated risk factors, we undertook a systematic review and meta-analysis compliant with PRISMA guidance. Databases and grey literatur... Read More about Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta-analysis.

Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies (2014)
Journal Article
Okoli, G., Otete, H., Beck, C., & Nguyen-Van-Tam, J. (2014). Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies. PLoS ONE, 9(12), https://doi.org/10.1371/journal.pone.0113633

Objectives: To assess the effectiveness of neuraminidase inhibitors for use in rapid containment of influenza. Method: We conducted a systematic review and meta-analysis in accordance with the PRISMA statement. Healthcare databases and sources of gr... Read More about Use of neuraminidase inhibitors for rapid containment of influenza: a systematic review and meta-analysis of individual and household transmission studies.

Neuraminidase inhibitors: who, when, where? (2014)
Journal Article
Nguyen-Van-Tam, J. S., Venkatesan, S., Muthuri, S. G., & Myles, P. R. (2015). Neuraminidase inhibitors: who, when, where?. Clinical Microbiology and Infection, 21(3), https://doi.org/10.1016/j.cmi.2014.11.020

Although the neuraminidase inhibitors (NIs), oseltamivir and zanamivir were first licensed in 1999, their clinical effectiveness is still hotly debated. Two rigorous systematic reviews and meta-analyses of the data from clinical trials conducted in c... Read More about Neuraminidase inhibitors: who, when, where?.

Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis (2014)
Journal Article
Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J. S., & Lim, W. S. (2015). Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis. Journal of Infectious Diseases, 212(2), 183-194. https://doi.org/10.1093/infdis/jiu645

Background: Most studies have reported that corticosteroid therapy adversely influences influenza-related outcomes. Methods: Electronic databases were searched from inception to March 2013 for experimental and observational studies investigating s... Read More about Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis.

A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims (2014)
Journal Article
Wang, M., Barasheed, O., Rashid, H., Booy, R., El Bashir, H., Haworth, E., …Heron, L. (in press). A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims. Journal of Epidemiology and Global Health, 5(2), https://doi.org/10.1016/j.jegh.2014.08.002

BACKGROUND: Cost-effective interventions are needed to control the transmission of viral respiratory tract infections (RTIs) in mass gatherings. Facemasks are a promising preventive measure, however, previous studies on the efficacy of facemasks have... Read More about A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims.

Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom (2014)
Journal Article
Elderfield, R. A., Watson, S. J., Godlee, A., Adamson, W. E., Thompson, C. I., Dunning, J., …Nguyen-Van-Tam, J. (in press). Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom. Journal of Virology, 88(22), https://doi.org/10.1128/JVI.01636-14

The influenza pandemic that emerged in 2009 provided an unprecedented opportunity to study adaptation of a virus recently acquired from an animal source during human transmission. In the United Kingdom, the novel virus spread in three temporally dist... Read More about Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom.

Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers (2014)
Journal Article
Barasheed, O., Rashid, H., Heron, L., Ridda, I., Haworth, E., Nguyen-Van-Tam, J. S., …Booy, R. (2014). Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers. Journal of Travel Medicine, 21(6), https://doi.org/10.1111/jtm.12146

Background: Hajj is the largest annual mass gathering where the risk of respiratory infection is high. Although the Saudi Arabian authority recommends influenza vaccination for Hajj pilgrims, the uptake is variable. Influenza vaccine uptake data amon... Read More about Influenza vaccination among Australian Hajj pilgrims: uptake, attitudes, and barriers.

The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis (2014)
Journal Article
Convalescent Plasma Study Group, Mair-Jenkins, J., Saavedra-Campos, M., Baillie, J. K., Cleary, P., Khaw, F.-M., …Nguyen-Van-Tam, J. S. (2015). The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis. Journal of Infectious Diseases, 211(1), 80-90. https://doi.org/10.1093/infdis/jiu396

Background: Administration of convalescent plasma, serum, or hyperimmune immunoglobulin may be of clinical benefit for treatment of severe acute respiratory infections (SARIs) of viral etiology. We conducted a systematic review and exploratory meta-a... Read More about The Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis.

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study (2014)
Journal Article
Hayward, A. C., Fragaszy, E. B., Bermingham, A., Wang, L., Copas, A., Edmunds, W. J., …Zambon, M. (in press). Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respiratory Medicine, 2(6), https://doi.org/10.1016/s2213-2600%2814%2970034-7

BACKGROUND: Assessment of the effect of influenza on populations, including risk of infection, illness if infected, illness severity, and consultation rates, is essential to inform future control and prevention. We aimed to compare the community burd... Read More about Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study.

The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident (2013)
Journal Article
Puleston, R. L., Mallaghan, C. M., Modha, D. E., Hunter, P. R., Nguyen-Van-Tam, J. S., Regan, C. M., …Chalmers, R. M. (2014). The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident. Journal of Water and Health, 12(1), https://doi.org/10.2166/wh.2013.097

Background: We report the first identified outbreak of cryptosporidiosis with Cryptosporidium cuniculus following a water quality incident in Northamptonshire, UK. Methods: A standardised, enhanced Cryptosporidium exposure questionnaire was adminis... Read More about The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident.