All Outputs (4)

The adaptive immune response to Trichuris in wild versus laboratory mice: An established model system in context (2024)
Journal Article
Mair, I., Fenn, J., Wolfenden, A., Lowe, A. E., Bennett, A., Muir, A., …Else, K. J. (2024). The adaptive immune response to Trichuris in wild versus laboratory mice: An established model system in context. PLoS Pathogens, 20(4), Article e1012119. https://doi.org/10.1371/journal.ppat.1012119

Laboratory model organisms have provided a window into how the immune system functions. An increasing body of evidence, however, suggests that the immune responses of naive laboratory animals may differ substantially to those of their wild counterpar... Read More about The adaptive immune response to Trichuris in wild versus laboratory mice: An established model system in context.

Discrete patterns of microbiome variability across timescales in a wild rodent population (2023)
Journal Article
Fenn, J., Taylor, C., Goertz, S., Wanelik, K. M., Paterson, S., Begon, M., …Bradley, J. (2023). Discrete patterns of microbiome variability across timescales in a wild rodent population. BMC Microbiology, 23, Article 87. https://doi.org/10.1186/s12866-023-02824-x

Mammalian gastrointestinal microbiomes are highly variable, both within individuals and across populations, with changes linked to time and ageing being widely reported. Discerning patterns of change in wild mammal populations can therefore prove cha... Read More about Discrete patterns of microbiome variability across timescales in a wild rodent population.

Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale (2019)
Journal Article
Goertz, S., de Menezes, A. B., Birtles, R. J., Fenn, J., Lowe, A. E., MacColl, A. D., …Taylor, C. H. (2019). Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale. PLoS ONE, 14(9), Article e0222501. https://doi.org/10.1371/journal.pone.0222501

The composition of the mammalian gut microbiota can be influenced by a multitude of environmental variables such as diet and infections. Studies investigating the effect of these variables on gut microbiota composition often sample across multiple se... Read More about Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale.

Immune state is associated with natural dietary variation in wild mice Mus musculus domesticus (2019)
Journal Article
Taylor, C. H., Young, S., Fenn, J., Lamb, A. L., Lowe, A. E., Poulin, B., …Bradley, J. E. (2019). Immune state is associated with natural dietary variation in wild mice Mus musculus domesticus. Functional Ecology, 33(8), 1425-1435. https://doi.org/10.1111/1365-2435.13354

1. The ability, propensity and need to mount an immune response vary both among individuals and within a single individual over time.

2. A wide array of parameters have been found to influence immune state in carefully controlled experiments, but... Read More about Immune state is associated with natural dietary variation in wild mice Mus musculus domesticus.