Epithelial Interleukin‐1 Receptor‐Like‐1 Activation Is Contingent on Interleukin‐33 Isoforms and Asthma‐Related Receptor Variation
(2024)
Journal Article
Portelli, M., Ketelaar, M., Bates, S., Csomor, E., Shaw, D., Emsley, J., Brightling, C., Hall, I., Affleck, K., Edwards, M., Nawijn, M., Koppelman, G., Van Oosterhout, A., & Sayers, I. (2024). Epithelial Interleukin‐1 Receptor‐Like‐1 Activation Is Contingent on Interleukin‐33 Isoforms and Asthma‐Related Receptor Variation. Clinical and Experimental Allergy, https://doi.org/10.1111/cea.14562
Introduction: The interleukin-33/interleukin-1 receptor-like-1 (IL-33/IL1RL1) signalling pathway is implicated in asthma pathogenesis, with IL1RL1 nonsynonymous genetic polymorphisms associated with disease risk. We aimed to determine these variants'... Read More about Epithelial Interleukin‐1 Receptor‐Like‐1 Activation Is Contingent on Interleukin‐33 Isoforms and Asthma‐Related Receptor Variation.