All Outputs (96)

Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study (2014)
Journal Article
West, J., Fleming, K. M., Tata, L. J., Card, T. R., & Crooks, C. J. (2014). Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study. American Journal of Gastroenterology, 109(5), 757-768. https://doi.org/10.1038/ajg.2014.55

OBJECTIVES: Few studies have quantified the incidence and prevalence of celiac disease (CD) and dermatitis herpetiformis (DH) nationally and regionally by time and age groups. Understanding this epidemiology is crucial for hypothesizing about causes... Read More about Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study.

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England (2014)
Journal Article
Walker, A., West, J., Card, T. R., Humes, D., & Grainge, M. J. (2014). Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England. Journal of Thrombosis and Haemostasis, 12(5), https://doi.org/10.1111/jth.12533

BACKGROUND: Patients with colorectal cancer are at high risk of developing venous thromboembolism (VTE), and recent international guidelines have advised extended prophylaxis for some of these patients following surgery or during chemotherapy. Howeve... Read More about Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England.

The epidemiology of irritable bowel syndrome (2014)
Journal Article
Canavan, C., West, J., & Card, T. R. (2014). The epidemiology of irritable bowel syndrome. Clinical Epidemiology, 6, https://doi.org/10.2147/CLEP.S40245

Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how this impacts epidemiological measurements. Depending on the dia... Read More about The epidemiology of irritable bowel syndrome.

1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study (2014)
Journal Article
Ratib, S., Fleming, K. M., Crooks, C. J., Aithal, G. P., & West, J. (2014). 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study. Journal of Hepatology, 60(2), https://doi.org/10.1016/j.jhep.2013.09.027

BACKGROUND & AIMS:
Large, population-based studies that have included the full spectrum of cirrhosis estimating survival, taking into account time-at-risk are lacking. We aimed to report 1- and 5-year average survival rates for people with cirrhosis... Read More about 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study.

Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer (2014)
Journal Article
Ratib, S., West, J., Crooks, C. J., & Fleming, K. M. (2014). Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer. American Journal of Gastroenterology, 109(2), https://doi.org/10.1038/ajg.2013.405

OBJECTIVES:
There is no routine registration of the occurrence of newly diagnosed cases of cirrhosis in the United Kingdom. This study seeks to determine precise estimates and trends of the incidence of cirrhosis in England, and directly compare the... Read More about Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer.

How to read a case-control study (2014)
Book Chapter
West, J., Tata, L. J., & Card, T. R. (2014). How to read a case-control study. In N. J. Talley, G. R. Locke III, P. Moayyedi, J. West, A. C. Ford, & Y. A. Saito (Eds.), GI Epidemiology: Diseases and Clinical Methodology (30-38). (Second edition). Wiley. https://doi.org/10.1002/9781118727072.ch3

Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England (2013)
Journal Article
Sultan, A. A., West, J., Tata, L. J., Fleming, K. M., Nelson-Piercy, C., & Grainge, M. J. (2013). Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England. BMJ, 347(7935), Article 11. https://doi.org/10.1136/bmj.f6099

Objective: To examine the potential for preventing venous
thromboembolism during and after antepartum hospital admissions in pregnant women.

Design: Cohort study using linked primary (Clinical Practice Research Datalink) and secondary (Hospital E... Read More about Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England.

The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis (2013)
Journal Article
Sultan, A. A., Tata, L. J., Grainge, M. J., & West, J. (2013). The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis. PLoS ONE, 8(7), Article e70310. https://doi.org/10.1371/journal.pone.0070310

Background: Recent linkage between primary and secondary care data has provided valuable information for studying
heath outcomes that may initially present in different health care settings. The aim of this study was therefore, twofold: to use linke... Read More about The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis.

Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding (2013)
Journal Article
Crooks, C. J., West, J., & Card, T. R. (2013). Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding. Gastroenterology, 144(7), Article 1384-1393.e2. https://doi.org/10.1053/j.gastro.2013.02.040

Background & Aims
The incidence of upper gastrointestinal bleeding (GIB) has not been reduced despite the decreasing incidence of peptic ulcers, strategies to eradicate Helicobacter pylori infection, and prophylaxis against ulceration from nonsteroi... Read More about Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding.

The communication of a secondary care diagnosis of autoimmune hepatitis to primary care practitioners: a population-based study (2013)
Journal Article
Varyani, F., Card, T. R., Kaye, P., Aithal, G. P., & West, J. (2013). The communication of a secondary care diagnosis of autoimmune hepatitis to primary care practitioners: a population-based study. BMC Health Services Research, 13(161), Article 161. https://doi.org/10.1186/1472-6963-13-161

Background
Autoimmune Hepatitis is a chronic liver disease which affects young people and can result in liver failure leading to death or transplantation yet there is a lack of information on the incidence and prevalence of this disease and its natu... Read More about The communication of a secondary care diagnosis of autoimmune hepatitis to primary care practitioners: a population-based study.

Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study (2013)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2013). Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study. PLoS Medicine, 10(4), Article e1001437. https://doi.org/10.1371/journal.pmed.1001437

Background
It is unclear whether an upper gastrointestinal bleed is an isolated gastrointestinal event or an indicator of a deterioration in a patient's overall health status. Therefore, we investigated the excess causes of death in individuals afte... Read More about Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study.

Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis (2012)
Journal Article
Horsted, F., West, J., & Grainge, M. J. (2012). Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis. PLoS Medicine, 9(7), Article e1001275. https://doi.org/10.1371/journal.pmed.1001275

Background: People with cancer are known to be at increased risk of venous thromboembolism (VTE), and this risk is believed to vary according to cancer type, stage of disease, and treatment modality. Our purpose was to summarise the existing literatu... Read More about Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis.

Independent risk factors for injury in pre-school children: three population-based nested case-control studies using routine primary care data (2012)
Journal Article
Orton, E., Kendrick, D., West, J., & Tata, L. J. (2012). Independent risk factors for injury in pre-school children: three population-based nested case-control studies using routine primary care data. PLoS ONE, 7(4), Article e35193. https://doi.org/10.1371/journal.pone.0035193

Background: Injuries in childhood are largely preventable yet an estimated 2,400 children die every day because of injury and violence. Despite this, the factors that contribute to injury occurrence have not been quantified at the population scale us... Read More about Independent risk factors for injury in pre-school children: three population-based nested case-control studies using routine primary care data.

All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study (2011)
Journal Article
Fleming, K. M., Aithal, G. P., Card, T. R., & West, J. (2012). All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study. Liver International, 32(1), https://doi.org/10.1111/j.1478-3231.2011.02517.x

Background: Mortality due to cirrhosis has tripled over the last 30 years in the UK. However, we lack adequate, contemporary, population-based estimates of the excess mortality patients who are at risk compared with the general population.
Aim: To d... Read More about All-cause mortality in people with cirrhosis compared with the general population: a population-based cohort study.

Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: A population-based cohort study (2007)
Journal Article
Jackson, H., Solaymani-Dodaran, M., Card, T. R., Aithal, G. P., Logan, R., & West, J. (2007). Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: A population-based cohort study. Hepatology, 46(4), 1131-1137. https://doi.org/10.1002/hep.21795

There is debate over the mortality and malignancy risk in people with primary biliary cirrhosis (PBC) and whether this risk is reduced by use of ursodeoxycholic acid. To investigate this issue, we identified 930 people with PBC and 9,202 control subj... Read More about Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: A population-based cohort study.

Fracture Risk in People With Primary Biliary Cirrhosis: A Population-Based Cohort Study (2006)
Journal Article
Solaymani–Dodaran, M., Card, T. R., Aithal, G. P., & West, J. (2006). Fracture Risk in People With Primary Biliary Cirrhosis: A Population-Based Cohort Study. Gastroenterology, 131(6), 1752-1757. https://doi.org/10.1053/j.gastro.2006.09.012

Background & Aims: Controversy exists as to whether people with primary biliary cirrhosis (PBC) have an increased risk of developing osteoporosis and the extent to which this may translate into an increased risk of fracture. We have performed a coh... Read More about Fracture Risk in People With Primary Biliary Cirrhosis: A Population-Based Cohort Study.