All Outputs (94)

Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study (2016)
Journal Article
Sultan, A. A., West, J., Grainge, M. J., Riley, R. D., Tata, L. J., Stephansson, O., …Ludvigsson, J. F. (2016). Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study. BMJ, 355(i6253), https://doi.org/10.1136/bmj.i6253

Objective: To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum). Design: Cohort study. Setting: Records from England based Clinical Practice Research Datalink (CPRD)... Read More about Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study.

The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England (2016)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2016). The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England. PLoS ONE, 11(10), 1-16. https://doi.org/10.1371/journal.pone.0165507

Background: We have assessed whether the linkage between routine primary and secondary care records provided an opportunity to develop an improved population based co-morbidity score with the combined information on co-morbidities from both health ca... Read More about The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England.

The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study (2016)
Journal Article
Zingone, F., Abdul Sultan, A., Crooks, C. J., Tata, L. J., Ciacci, C., & West, J. (in press). The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study. Alimentary Pharmacology and Therapeutics, 44(1), https://doi.org/10.1111/apt.13652

Background: Patients with coeliac disease are considered as individuals for whom pneumococcal vaccination is advocated. Aim: To quantify the risk of community-acquired pneumonia among patients with coeliac disease, assessing whether vaccination ag... Read More about The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study.

Calculating total health service utilisation and costs from routinely collected electronic health records using the example of patients with irritable bowel syndrome before and after their first gastroenterology appointment (2015)
Journal Article
Canavan, C., West, J., & Card, T. R. (in press). Calculating total health service utilisation and costs from routinely collected electronic health records using the example of patients with irritable bowel syndrome before and after their first gastroenterology appointment. PharmacoEconomics, 34(2), https://doi.org/10.1007/s40273-015-0339-y

INTRODUCTION: Health economic models are increasingly important in funding decisions but most are based on data, which may therefore not represent the general population. We sought to establish the potential of real-world data available within the Cl... Read More about Calculating total health service utilisation and costs from routinely collected electronic health records using the example of patients with irritable bowel syndrome before and after their first gastroenterology appointment.

Change in quality of life for patients with irritable bowel syndrome following referral to a gastroenterologist: a cohort study (2015)
Journal Article
Canavan, C., West, J., & Card, T. R. (2015). Change in quality of life for patients with irritable bowel syndrome following referral to a gastroenterologist: a cohort study. PLoS ONE, 10(10), Article e0139389. https://doi.org/10.1371/journal.pone.0139389

BACKGROUND: Irritable bowel syndrome (IBS), a chronic functional condition, considerably reduces quality of life (QoL) and referral to gastroenterology is common. Until now, however, the impact of seeing a gastroenterologist for IBS on patients’ QoL... Read More about Change in quality of life for patients with irritable bowel syndrome following referral to a gastroenterologist: a cohort study.

Variation in the risk of venous thromboembolism following colectomy (2015)
Journal Article
Humes, D., Walker, A., Blackwell, J., Hunt, B., & West, J. (2015). Variation in the risk of venous thromboembolism following colectomy. British Journal of Surgery, 102(13), https://doi.org/10.1002/bjs.9923

Background: Guidelines recommend extended thromboprophylaxis following colectomy for malignant disease, but not for non-malignant disease. The aim of this study was to determine absolute and relative rates of venous thromboembolism (VTE) following co... Read More about Variation in the risk of venous thromboembolism following colectomy.

Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis (2015)
Journal Article
Abdul Sultan, A., Crooks, C. J., Card, T. R., Tata, L. J., Fleming, K. M., & West, J. (2015). Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis. Gut, 64(8), https://doi.org/10.1136/gutjnl-2014-308285

INTRODUCTION: Quantifying excess cause-specific mortality among people with coeliac disease (CD) compared with the general population accounting for competing risks will allow accurate information to be given on risk of death from specific causes.... Read More about Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis.

A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort (2015)
Journal Article
Crooks, C. J., West, J., & Card, T. R. (2015). A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort. BMJ Open, 5(6), Article e007974. https://doi.org/10.1136/bmjopen-2015-007974

OBJECTIVE: Hospital admission records provide snapshots of clinical histories for a subset of the population admitted to hospital. In contrast, primary care records provide continuous clinical histories for complete populations, but might lack detail... Read More about A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort.

Risk of venous thromboembolism in children after general surgery (2015)
Journal Article
Humes, D. J., Nordenskjöld, A., Walker, A. J., West, J., & Ludvigsson, J. F. (in press). Risk of venous thromboembolism in children after general surgery. Journal of Pediatric Surgery, 50(11), https://doi.org/10.1016/j.jpedsurg.2015.05.010

Background/purpose: The purpose of the study was to determine absolute and relative rates of venous thromboembolism (VTE) following general surgical procedures in children compared to the general population. Methods: We analyzed data from all pat... Read More about Risk of venous thromboembolism in children after general surgery.

Socioeconomic variation in the incidence of childhood coeliac disease in the UK (2015)
Journal Article
Zingone, F., West, J., Crooks, C. J., Fleming, K. M., Card, T. R., Ciacci,, C., & Tata, L. J. (2015). Socioeconomic variation in the incidence of childhood coeliac disease in the UK. Archives of Disease in Childhood, 100(5), https://doi.org/10.1136/archdischild-2014-307105

BACKGROUND: Serological studies indicate that evidence of coeliac disease (CD) exists in about 1% of all children, but we lack estimates of current diagnostic patterns among children and how they vary by socioeconomic group. METHODS: We identifie... Read More about Socioeconomic variation in the incidence of childhood coeliac disease in the UK.

Incidence and distribution of coeliac disease in Campania (Italy): 2011–2013 (2015)
Journal Article
Zingone, F., West, J., Auricchio, R., Maria Bevilacqua, R., Bile, G., Borgheresi, P., …Ciacci, C. (2015). Incidence and distribution of coeliac disease in Campania (Italy): 2011–2013. United European Gastroenterology Journal, 3(2), https://doi.org/10.1177/2050640615571021

BACKGROUND: There exists a wide variation in the reported incidence of coeliac disease in recent decades. We aimed to evaluate the incidence rate of coeliac diagnoses performed in an Italian region, Campania, between 2011 and 2013 and its variation t... Read More about Incidence and distribution of coeliac disease in Campania (Italy): 2011–2013.

Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England (2015)
Journal Article
Zingone, F., Sultan, A. A., Humes, D., & West, J. (2015). Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England. Annals of Surgery, 261(2), https://doi.org/10.1097/sla.0000000000000780

Objective: To determine the absolute and relative risk of acute appendicitis during the antepartum and postpartum periods compared with the time outside pregnancy among women of childbearing age. Background: Acute appendicitis is the most common... Read More about Risk of acute appendicitis in and around pregnancy: a population-based cohort study from England.

Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5 (2014)
Journal Article
Orton, E., Kendrick, D., West, J., & Tata, L. J. (2014). Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5. PLoS ONE, 9(10), Article e111631. https://doi.org/10.1371/journal.pone.0111631

BACKGROUND: Injury is a significant cause of childhood death and can result in substantial long-term disability. Injuries are more common in children from socio-economically deprived families, contributing to health inequalities between the most and... Read More about Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5.

The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study (2014)
Journal Article
Canavan, C., Card, T. R., & West, J. (2014). The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study. PLoS ONE, 9(9), Article e106478. https://doi.org/10.1371/journal.pone.0106478

BACKGROUND: Guidelines recommend Irritable Bowel Syndrome (IBS) diagnosis and management in primary care with minimal investigations; however little evidence exists regarding risk of organic gastrointestinal conditions following diagnosis of IBS and... Read More about The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study.

Review article: the economic impact of the irritable bowel syndrome (2014)
Journal Article
Canavan, C., West, J., & Card, T. R. (in press). Review article: the economic impact of the irritable bowel syndrome. Alimentary Pharmacology and Therapeutics, 40(9), https://doi.org/10.1111/apt.12938

Background: Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal system affecting a large number of people worldwide. Whilst it has no attributable mortality, it has substantial impact on patients' quality of life (... Read More about Review article: the economic impact of the irritable bowel syndrome.

Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England (2014)
Journal Article
Abdul Sultan, A., Grainge, M. J., West, J., Fleming, K. M., Nelson-Piercy, C., & Tata, L. J. (in press). Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England. Blood, 124(18), https://doi.org/10.1182/blood-2014-05-572834

For women with preeclampsia, BMI >30 kg/m2, infection, or those having cesarean delivery, VTE risk remained elevated for 6 weeks postpartum.For women with postpartum hemorrhage or preterm birth, the relative rate of VTE was only increased for the fir... Read More about Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England.

Women with celiac disease present with fertility problems no more often than women in the general population (2014)
Journal Article
Dhalwani, N. N., West, J., Sultan, A. A., Ban, L., & Tata, L. J. (in press). Women with celiac disease present with fertility problems no more often than women in the general population. Gastroenterology, 147(6), Article 1267-1274.e1. https://doi.org/10.1053/j.gastro.2014.08.025

BACKGROUND & AIMS: Studies have associated infertility with celiac disease. However, these included small numbers of women attending infertility specialist services and subsequently screened for celiac disease, and therefore may not have been represe... Read More about Women with celiac disease present with fertility problems no more often than women in the general population.

Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study (2014)
Journal Article
West, J., Fleming, K. M., Tata, L. J., Card, T. R., & Crooks, C. J. (2014). Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study. American Journal of Gastroenterology, 109(5), 757-768. https://doi.org/10.1038/ajg.2014.55

OBJECTIVES: Few studies have quantified the incidence and prevalence of celiac disease (CD) and dermatitis herpetiformis (DH) nationally and regionally by time and age groups. Understanding this epidemiology is crucial for hypothesizing about causes... Read More about Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study.

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England (2014)
Journal Article
Walker, A., West, J., Card, T. R., Humes, D., & Grainge, M. J. (2014). Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England. Journal of Thrombosis and Haemostasis, 12(5), https://doi.org/10.1111/jth.12533

BACKGROUND: Patients with colorectal cancer are at high risk of developing venous thromboembolism (VTE), and recent international guidelines have advised extended prophylaxis for some of these patients following surgery or during chemotherapy. Howeve... Read More about Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England.

The epidemiology of irritable bowel syndrome (2014)
Journal Article
Canavan, C., West, J., & Card, T. R. (2014). The epidemiology of irritable bowel syndrome. Clinical Epidemiology, 6, https://doi.org/10.2147/CLEP.S40245

Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how this impacts epidemiological measurements. Depending on the dia... Read More about The epidemiology of irritable bowel syndrome.