All Outputs (2)

Monoclonal antibodies targeting LecLex-related glycans with potent antitumor activity (2015)
Journal Article

© 2015 American Association for Cancer Research. Purpose: To produce antitumor monoclonal antibodies (mAbs) targeting glycans as they are aberrantly expressed in tumors and are coaccessory molecules for key survival pathways. Experimental Design: Two... Read More about Monoclonal antibodies targeting LecLex-related glycans with potent antitumor activity.

Structural biology of antibody recognition of carbohydrate epitopes and potential uses for targeted cancer immunotherapies (2015)
Journal Article

Monoclonal antibodies represent the most successful class of biopharmaceuticals for the treatment of cancer. Mechanisms of action of therapeutic antibodies are very diverse and reflect their ability to engage in antibody-dependent effector mechanisms... Read More about Structural biology of antibody recognition of carbohydrate epitopes and potential uses for targeted cancer immunotherapies.