An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids

Amey, Joanna S.; O'Reilly, Andrias O.; Burton, Mark J.; Puinean, Alin M.; Mellor, Ian R.; Duce, Ian R.; Field, Linda M.; Wallace, B.A.; Williamson, Martin S.; Davies, T.G. Emyr

doi:10.1016/j.febslet.2015.01.020

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An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids (2015)
Journal Article
Amey, J. S., O'Reilly, A. O., Burton, M. J., Puinean, A. M., Mellor, I. R., Duce, I. R., …Davies, T. E. (2015). An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids. FEBS Letters, 589(5), 598-607. https://doi.org/10.1016/j.febslet.2015.01.020

We describe the identification in aphids of a unique heterodimeric voltage-gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin. We demonstrate that this channel h... Read More about An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids.